Publications by authors named "Yifan Zhai"

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Safety, tolerability, and pharmacokinetics of lisaftoclax (APG-2575)-based therapy in patients with chronic lymphocytic leukemia: Phase 1b/2 study.
Matthew S Davids, Asher Chanan-Khan, Sikander Ailawadhi, Vladimir Ivanov, Ganna Usenko, Yifan Zhai

Med· December 2025

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Targeting activation of intrinsic apoptotic pathway through Mcl-1 inhibition to delay emergence of acquired resistance of lung cancer to osimertinib.
Guangzhi Ma, Dongsheng Wang, Yunfu Deng, Weijia Huang, Yifan Zhai

Cancer Lett· November 2025

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Safety, pharmacokinetic, pharmacodynamic, and efficacy properties of orally administered APG-2449 in patients with advanced and non-small-cell lung cancer: a multicentre, open-label, single-arm phase 1 trial.
Yuxiang Ma, Zhengbo Song, Jianhua Chen, Yanqiu Zhao, Wenfeng Fang, Yifan Zhai

EClinicalMedicine· November 2025

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Olverembatinib, a multikinase inhibitor that modulates lipid metabolism, in advanced succinate dehydrogenase-deficient gastrointestinal stromal tumors: a phase 1b study and translational research.
Hai-Bo Qiu, Zhiyan Liang, Jing Yang, Ye Zhou, Zhi-Wei Zhou, Yifan Zhai

Signal Transduct Target Ther· November 2025

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Bombus terrestris as biocontrol agent vector to suppress Botrytis cinerea in greenhouse tomato.
Yan Liu, Guoyu Li, Ruijuan Wang, Long Su, Shan Zhao, Yifan Zhai

Pest Manag Sci· October 2025

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A phase 1 trial of APG-1387, an IAP antagonist, with nab-paclitaxel and gemcitabine in patients with refractory metastatic pancreatic cancer.
Si Shi, Jian Zhang, Rujiao Liu, Shuiping Gao, Jin Xu, Yifan Zhai

Cell Rep Med· October 2025

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Gut microbiota shape gene regulatory networks to direct intestinal stem cell differentiation trajectories in Apis mellifera.
Huiling Liu, Liang Meng, Jie Ma, Bingkun Yang, Hao Wang, Yifan Zhai

Insect Sci· September 2025

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Chromosomal-level genome assembly of Drosophila suzukii Matsumura (Diptera: Drosophilidae).
Ruijuan Wang, Huanhuan Gao, Shan Zhao, Xiaoyan Dai, Zhenjuan Yin, Yifan Zhai

Sci Data· September 2025

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Interaction effects of high temperature and ozone on cardiovascular disease mortality in Chengdu, 2014-2023.
Jinqiu Yao, Jingwen Sun, Dan Kuang, Wen Qian, Li Luo, Yifan Zhai

Front Public Health· July 2025

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Chromosomal-level genome assembly of solitary bee pollinator Osmia excavata Alfken (Hymenoptera: Megachilidae).
Ruijuan Wang, Xiaoyan Dai, Shan Zhao, Zhenjuan Yin, Long Su, Yifan Zhai

Sci Data· May 2025

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Olverembatinib in chronic myeloid leukemia-Review of historical development, current status, and future research.
Hagop Kantarjian, Yifan Zhai, Vivian G Oehler, Omer Jamy, Paul B Koller

Cancer· April 2025

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Single-nucleus and spatial transcriptomics identify brain landscape of gene regulatory networks associated with behavioral maturation in honeybees.
Xiaohuan Mu, Zijing Zhang, Qun Liu, Jie Ma, Yating Qin, Yifan Zhai

Nat Commun· April 2025

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Genetic differentiation and adaptive evolution of buff-tailed bumblebees in Asia.
Long Su, Lele Ding, Paul H Williams, Yan Liu, Ruijuan Wang, Yifan Zhai

Insect Sci· April 2025

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A chromosomal-level genome assembly of Trichogramma chilonis Ishii, 1941 (Hymenoptera: Trichogrammatidae).
Chengxing Wang, Zhenjuan Yin, Yan Liu, Xiaoyan Dai, Shan Zhao, Yifan Zhai

Sci Data· March 2025

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Dextran sodium sulfate-induced colitis-like gut permeability and dysbiosis in honeybees.
Ya Li, Jieteng Chen, Xiaohuan Mu, Xiaofei Wang, Yan Liu, Yifan Zhai

Insect Sci· February 2025

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Olverembatinib After Failure of Tyrosine Kinase Inhibitors, Including Ponatinib or Asciminib: A Phase 1b Randomized Clinical Trial.
Elias Jabbour, Vivian G Oehler, Paul B Koller, Omer Jamy, Elza Lomaia, Yifan Zhai

JAMA Oncol· January 2025

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Megoura crassicauda promote the ability of Vicia faba L. to remediate cadmium pollution of water and soil.
Sijing Wan, Shasha Wang, Yan Li, Yexin Xie, Qimei Li, Yifan Zhai

Ecotoxicol Environ Saf· January 2025

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Bivalent SMAC mimetic APG-1387 reduces HIV reservoirs and limits viral rebound in humanized mice.
Jaspreet Jain, Tram N Q Pham, Sharmin Begum, Maria Carmen Romero-Medina, Nicolas Bellini, Yifan Zhai

iScience· December 2024

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The Selection and Validation of Reference Genes for RT-qPCR Analysis of the Predatory Natural Enemy (Hemiptera: Anthocoridae).
Chengxing Wang, Zhenjuan Yin, Yu Wang, Yan Liu, Shan Zhao, Yifan Zhai

Insects· November 2024

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Stress Response of Aphid Population Under Combined Stress of Cadmium and Lead and Its Effects on Development of .
Shasha Wang, Qimei Li, Yan Li, Sijing Wan, Zhenjuan Yin, Yifan Zhai

Int J Mol Sci· October 2024

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Pharmacokinetics of olverembatinib (HQP1351) in the presence of a strong CYP3A4 inhibitor (itraconazole) or inducer (rifampin) in healthy volunteers.
Hengbang Wang, Yun Yang, Zi Chen, Lei Fu, Min Yu, Yifan Zhai

Clin Transl Sci· September 2024

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Insulin Signaling Pathway Mediates FoxO-Pepck Axis Regulation of Glucose Homeostasis in .
Shuting Zang, Ruijuan Wang, Yan Liu, Shan Zhao, Long Su, Yifan Zhai

Int J Mol Sci· September 2024

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Identification of the mutual gliding locus as a factor for gut colonization in non-native bee hosts using the ARTP mutagenesis.
Yujie Meng, Xue Zhang, Yifan Zhai, Yuan Li, Zenghua Shao

Microbiome· May 2024

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Synergistic effects of Smac mimetic APG-1387 with anti-PD-1 antibody are attributed to increased CD3 + NK1.1 + cell recruitment secondary to induction of cytokines from tumor cells.
Wentao Pan, Qiuyun Luo, Eric Liang, Mude Shi, Jian Sun, Yifan Zhai

Cancer Cell Int· May 2024

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Molecular Correlates of Diapause in .
Xiaoyan Dai, Yu Wang, Yan Liu, Ruijuan Wang, Long Su, Yifan Zhai

Insects· April 2024

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