Publications by authors named "Yiling Du"

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Genome mining and characterization of a heme-dependent enzyme catalyzing intermolecular Nitrogen-Nitrogen bond formation in hydrazinosuccinic acid biosynthesis.
Jingkun Shi, Zhijie Zhao, Jian Yang, Ziyang Cheng, Hu Li, Yi-Ling Du

Synth Syst Biotechnol· December 2025

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Structural and Mechanistic Insights into Bacterial Hydrazine Biosynthesis.
Guiyun Zhao, Huisi Huang, Yifan Li, Jian Yang, Yuan-Yang Guo, Yi-Ling Du

J Am Chem Soc· November 2025

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Conversion of a Heme-Dependent Dehydratase to a Piperazate Synthase Reveals the Role of the Heme Propionate Group in N-N Bond-Formation.
Melanie A Higgins, Nana Mirotadze, Xinjie Shi, Elesha R Hoffarth, Yi-Ling Du

J Am Chem Soc· October 2025

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Hypothesis for Molecular Evolution in the Pre-Cellular Stage of the Origin of Life.
Yong Wang, Yiling Du

Wiley Interdiscip Rev RNA· January 2025

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Stepwise increase of fidaxomicin in an engineered heterologous host through multi-level metabolic engineering.
Huang Xie, Yi-Ting Su, Qing-Ting Bu, Yue-Ping Li, Qing-Wei Zhao, Yi-Ling Du

Synth Syst Biotechnol· December 2024

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Discovery of a Bacterial Hydrazine Transferase That Constructs the N-Aminolactam Pharmacophore in Albofungin Biosynthesis.
Wei Li, Ziyang Cheng, Zhijie Zhao, Hu Li, Yu Liu, Yi-Ling Du

J Am Chem Soc· May 2024

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Nitric oxide synthase-guided genome mining identifies a cytochrome P450 enzyme for olefin nitration in bacterial specialized metabolism.
Hu Li, Wei Li, Kaihui Song, Yu Liu, Guiyun Zhao, Yi-Ling Du

Synth Syst Biotechnol· March 2024

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Transcriptional regulation of the fidaxomicin gene cluster and cellular development in YP-1 by the pleiotropic regulator MtrA.
Huang Xie, Jing-Yi Ruan, Qing-Ting Bu, Yue-Ping Li, Yi-Ting Su, Yi-Ling Du

Microbiol Spectr· December 2023

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Conserved Enzymatic Cascade for Bacterial Azoxy Biosynthesis.
Jingkun Shi, Xin Zang, Zhijie Zhao, Zhuanglin Shen, Wei Li, Yi-Ling Du

J Am Chem Soc· December 2023

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Hydroxytryptophan biosynthesis by a family of heme-dependent enzymes in bacteria.
Xinjie Shi, Guiyun Zhao, Hu Li, Zhijie Zhao, Wei Li, Yi-Ling Du

Nat Chem Biol· November 2023

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Targeted genome mining for microbial antitumor agents acting through DNA intercalation.
Zhijie Zhao, Guiyun Zhao, Yi Chai, Wei Li, Kaihui Song, Yi-Ling Du

Synth Syst Biotechnol· September 2023

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Heterologous Reconstitution of Toxoflavin Biosynthesis Reveals Key Pathway Intermediates and a Cofactor-Independent Oxidase.
Kaihui Song, Wei Li, Zhijie Zhao, Hu Li, Yu Liu, Yi-Ling Du

Org Lett· April 2023

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Synthetic and biosynthetic routes to nitrogen-nitrogen bonds.
Hai-Yan He, Haruka Niikura, Yi-Ling Du, Katherine S Ryan

Chem Soc Rev· April 2022

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Probiotic Lactobacillus casei Shirota prevents acute liver injury by reshaping the gut microbiota to alleviate excessive inflammation and metabolic disorders.
Ren Yan, Kaicen Wang, Qiangqiang Wang, Huiyong Jiang, Yingfeng Lu, Yiling Du

Microb Biotechnol· January 2022

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Mechanism of the Immunomodulatory Effect of the Combination of Live , , , and on Immunocompromised Rats.
Longxian Lv, Deguang Mu, Yiling Du, Ren Yan, Huiyong Jiang

Front Immunol· December 2021

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Molecular basis of enzymatic nitrogen-nitrogen formation by a family of zinc-binding cupin enzymes.
Guiyun Zhao, Wei Peng, Kaihui Song, Jingkun Shi, Xingyu Lu, Yi-Ling Du

Nat Commun· December 2021

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Enzymatic Tailoring in Luzopeptin Biosynthesis Involves Cytochrome P450-Mediated Carbon-Nitrogen Bond Desaturation for Hydrazone Formation.
Xinjie Shi, Liming Huang, Kaihui Song, Guiyun Zhao, Yu Liu, Yi-Ling Du

Angew Chem Int Ed Engl· September 2021

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Genome-based rational engineering of Actinoplanes deccanensis for improving fidaxomicin production and genetic stability.
Yue-Ping Li, Qing-Ting Bu, Ji-Feng Li, Huang Xie, Yi-Ting Su, Yi-Ling Du

Bioresour Technol· June 2021

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The serum metabolome of COVID-19 patients is distinctive and predictive.
Ding Shi, Ren Yan, Longxian Lv, Huiyong Jiang, Yingfeng Lu, Yiling Du

Metabolism· May 2021

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PCR & Go: A Pre-installed Expression Chassis for Facile Integration of Multi-Gene Biosynthetic Pathways.
Mingming Qi, Bei Zhang, Lihong Jiang, Saijuan Xu, Chang Dong, Yi-Ling Du

Front Bioeng Biotechnol· January 2021

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Expansion of Gamma-Butyrolactone Signaling Molecule Biosynthesis to Phosphotriester Natural Products.
Yuta Kudo, Takayoshi Awakawa, Yi-Ling Du, Peter A Jordan, Kaitlin E Creamer

ACS Chem Biol· December 2020

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The Biosynthetic Gene Cluster of Pyrazomycin-A C-Nucleoside Antibiotic with a Rare Pyrazole Moiety.
Guiyun Zhao, Shunyu Yao, Kristina W Rothchild, Tengfei Liu, Yu Liu, Yi-Ling Du

Chembiochem· March 2020

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Nitric oxide as a source for bacterial triazole biosynthesis.
Guiyun Zhao, Yuan-Yang Guo, Shunyu Yao, Xinjie Shi, Longxian Lv, Yi-Ling Du

Nat Commun· March 2020

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Convergent biosynthetic transformations to a bacterial specialized metabolite.
Yi-Ling Du, Melanie A Higgins, Guiyun Zhao, Katherine S Ryan

Nat Chem Biol· November 2019

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Molecular mechanism of azoxy bond formation for azoxymycins biosynthesis.
Yuan-Yang Guo, Zhen-Hua Li, Tian-Yu Xia, Yi-Ling Du, Xu-Ming Mao

Nat Commun· October 2019

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