Publications by authors named "Yong Wee"

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Spatial single-cell profiling identifies protein kinase Cδ-expressing microglia with anti-tumor function in glioblastoma.
Reza Mirzaei, Reid McNeil, Charlotte D'Mello, Britney Wong, Susobhan Sarkar, V Wee Yong

iScience· January 2026

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Targeted deletion of EMMPRIN in microglia/macrophages mitigates neuronal death in intracerebral hemorrhage.
Zhe Li, Xiangyu Zhang, Maryam Mobarakabadi, Yang Liu, Ruixue Wei, V Wee Yong

Mol Neurodegener· December 2025

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Apelin-13 Attenuates Blood-Brain Barrier Dysfunction Following Intracerebral Hemorrhage via Targeting the Keap1/Nrf2 Signaling.
Pingping Guo, Rabeea Siddique, Juanfeng Qian, Lingxiao Qi, V Wee Yong

CNS Neurosci Ther· December 2025

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Apelin-13 attenuates microglia-mediated neuroinflammation following intracerebral hemorrhage via targeting JAK2/STAT3 signaling pathway.
Pingping Guo, Jingjing Li, Xiangyu Zhang, Qingli Wang, Yang Liu, V Wee Yong

Exp Neurol· December 2025

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Neuroprotective effects of urolithin a in a mouse model of intracerebral hemorrhage.
Yan Guo, Xiangyu Zhang, Jianzhong Deng, Qiuyang Su, Yuanyuan Liu, V Wee Yong

Neuropharmacology· November 2025

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EZHIP boosts neuronal-like synaptic gene programs and depresses polyamine metabolism.
Elham Hasheminasabgorji, Huey-Miin Chen, Taylor A Gatesman, Subhi Talal Younes, Gabrielle A Nobles, Wee Yong

Acta Neuropathol Commun· November 2025

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A phase I-II study of niacin in patients with newly diagnosed glioblastoma: safety and interim phase II analysis.
Gloria Roldan Urgoiti, Paula de Robles, Roger Y Tsang, Morgan Willson, Sunita Ghosh, V Wee Yong

J Neurooncol· November 2025

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Recycling gone wrong: how inflammation promotes neuronal stress.
Yifei Dong, V Wee Yong

Trends Pharmacol Sci· September 2025

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Bruton Tyrosine Kinase in Lesions of Multiple Sclerosis and 3 of Its Models.
Cenxiao Li, Marlene T Morch, Rianne Gorter, Brian Lozinski, Samira Ghorbani, V Wee Yong

Neurol Neuroimmunol Neuroinflamm· July 2025

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Cholesterol in the CNS: functions, recycling and remyelination.
Emily C Wuerch, V Wee Yong

J Neuroinflammation· July 2025

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Spermidine Exerts Neuroprotective Effects Following Intracerebral Hemorrhage in Mice Through Anti-Inflammation and Blood-Brain Barrier Protection.
Lingxiao Qi, Xiangyu Zhang, Yuanyuan Liu, Pingping Guo, Rabeea Siddique, V Wee Yong

J Inflamm Res· June 2025

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Neuroinflammation across neurological diseases.
Fu-Dong Shi, V Wee Yong

Science· June 2025

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Targeting extracellular matrix components to attenuate microglia neuroinflammation: A study of fibulin-2 and CSPGs in a model of multiple sclerosis.
Gurleen Randhawa, Maryam Mobarakabadi, Charlotte D'Mello, Marlene T Morch, Ping Zhang, V Wee Yong

J Neuroimmunol· March 2025

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GABA receptors regulate the neural stem cell potential of Pkd2l1 cerebrospinal fluid-contacting neurons via the PI3K/Akt signaling pathway.
Liang Cao, Wei-Hong Yan, Wenjun Pi, Yi Zhang, Yan-Xiang Xiong, V Wee Yong

Brain Res Bull· February 2025

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Therapeutic reduction of neurocan in murine intracerebral hemorrhage lesions promotes oligodendrogenesis and functional recovery.
Hongmin Li, Samira Ghorbani, Olayinka Oladosu, Ping Zhang, Frank Visser, V Wee Yong

J Neuroinflammation· January 2025

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The Learning Curve for Left Atrial Strain Analysis.
Natalie F A Edwards, Katherine Lau, Rebecca Sophios, Ian Hotham, Benjamin Fitzgerald, Yong Wee

J Am Soc Echocardiogr· October 2024

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Fenebrutinib, a Bruton's tyrosine kinase inhibitor, blocks distinct human microglial signaling pathways.
Julie Langlois, Simona Lange, Martin Ebeling, Will Macnair, Roland Schmucki, V Wee Yong

J Neuroinflammation· October 2024

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TULIPs decorate the three-dimensional genome of PFA ependymoma.
Michael J Johnston, John J Y Lee, Bo Hu, Ana Nikolic, Elham Hasheminasabgorji, V Wee Yong

Cell· September 2024

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Niacin produces an inconsistent treatment response in the EAE model of multiple sclerosis.
Emily C Wuerch, Reza Mirzaei, V Wee Yong

J Neuroimmunol· September 2024

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The refined Pathways to Cures Research Roadmap for multiple sclerosis cures.
Bruce F Bebo, Brenda L Banwell, Caroline C Whitacre, Timothy Coetzee, Ulrik Dalgas, V Wee Yong

Mult Scler· September 2024

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Pathogenic hypothalamic extracellular matrix promotes metabolic disease.
Cait A Beddows, Feiyue Shi, Anna L Horton, Sagar Dalal, Ping Zhang, V Wee Yong

Nature· September 2024

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The cerebroprotection and prospects of FNDC5/irisin in stroke.
Yuanyuan Liu, Yang Liu, Xiangyu Zhang, Gaili Yan, Lingxiao Qi, V Wee Yong

Neuropharmacology· August 2024

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Generating and Analyzing High-Parameter Histology Images with Histoflow Cytometry.
Rajiv W Jain, David A Elliott, V Wee Yong

J Vis Exp· June 2024

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From progression to progress: The future of multiple sclerosis.
Jiwon Oh, Paul S Giacomini, V Wee Yong, Fiona Costello, François Blanchette

J Cent Nerv Syst Dis· May 2024

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Fibulin-2 is an extracellular matrix inhibitor of oligodendrocytes relevant to multiple sclerosis.
Samira Ghorbani, Cenxiao Li, Brian M Lozinski, Dorsa Moezzi, Charlotte D'Mello, V Wee Yong

J Clin Invest· May 2024

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