Publications by authors named "Yonghong Wan"

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A universal boosting strategy for adoptive T cell therapy using a paired vaccine/chimeric antigen receptor.
Rebecca Burchett, Claire G Morris, Mira Ishak, Nickolas J Serniuck, Derek T Cummings, Yonghong Wan

Cancer Immunol Res· December 2025

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Pre-Encoded IFN-I Sensitivity Exacerbates Memory T Cell Senescence in Solid Tumors.
Andrew Nguyen, Scott R Walsh, Li Deng, Lan Chen, Yonghong Wan

Adv Sci (Weinh)· October 2025

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Level of Expression of MHCI-Presented Neoepitopes Influences Tumor Rejection by Neoantigen-Specific CD8+ T Cells.
Li Deng, Scott R Walsh, Andrew Nguyen, Jordon M Inkol, Michael J Westerveld, Yonghong Wan

Cancer Immunol Res· January 2025

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Exosomes From Human Umbilical Cord Stem Cells Suppress Macrophage-to-myofibroblast Transition, Alleviating Renal Fibrosis.
Qitong Guo, Ping Li, Meiling Chen, Yihang Yu, Yonghong Wan

Inflammation· December 2024

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Pyroptosis activates conventional type I dendritic cells to mediate the priming of highly functional anticancer T cells.
Jordon M Inkol, Michael J Westerveld, Shayla G Verburg, Scott R Walsh, Jodi Morrison, Yonghong Wan

J Immunother Cancer· April 2024

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The effect of comb length on the and properties of self-assembled poly(oligoethylene glycol methacrylate)-based block copolymer nanoparticles.
Andrew Singh, Andrew Lofts, Ramya Krishnan, Matthew Campea, Lan Chen, Yonghong Wan

Nanoscale Adv· April 2024

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Human umbilical cord mesenchymal stem cell exosomes alleviate acute kidney injury by inhibiting pyroptosis in rats and NRK-52E cells.
Yonghong Wan, Yihang Yu, Chengjun Yu, Jin Luo, Sheng Wen

Ren Fail· December 2023

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HDACi-dependent Microenvironmental Normalization Overcomes Tumor Burden-induced T-cell Exhaustion.
Andrew Nguyen, Dominique Brown, Ramya Krishnan, Donald Bastin, Li Deng, Yonghong Wan

Clin Cancer Res· October 2023

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Epigenetic modification of locus dictates immune recognition of nascent tumorigenic cells.
Jiadi Lv, Yabo Zhou, Nannan Zhou, Zhenfeng Wang, Jie Chen, Dianheng Wang, Yonghong Wan

Sci Transl Med· February 2023

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Oncolytic BHV-1 Is Sufficient to Induce Immunogenic Cell Death and Synergizes with Low-Dose Chemotherapy to Dampen Immunosuppressive T Regulatory Cells.
Maria Eugenia Davola, Olga Cormier, Alyssa Vito, Nader El-Sayes, Susan Collins, Yonghong Wan

Cancers (Basel)· February 2023

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HDACi promotes inflammatory remodeling of the tumor microenvironment to enhance epitope spreading and antitumor immunity.
Andrew Nguyen, Louisa Ho, Richard Hogg, Lan Chen, Scott R Walsh, Yonghong Wan

J Clin Invest· October 2022

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IFNAR blockade synergizes with oncolytic VSV to prevent virus-mediated PD-L1 expression and promote antitumor T cell activity.
Nader El-Sayes, Scott Walsh, Alyssa Vito, Amir Reihani, Kjetil Ask, Yonghong Wan

Mol Ther Oncolytics· June 2022

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Respiratory mucosal delivery of next-generation COVID-19 vaccine provides robust protection against both ancestral and variant strains of SARS-CoV-2.
Sam Afkhami, Michael R D'Agostino, Ali Zhang, Hannah D Stacey, Art Marzok, Fuan Wang, Yonghong Wan

Cell· March 2022

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A Combination of Chemotherapy and Oncolytic Virotherapy Sensitizes Colorectal Adenocarcinoma to Immune Checkpoint Inhibitors in a cDC1-Dependent Manner.
Nader El-Sayes, Alyssa Vito, Omar Salem, Samuel Tekeste Workenhe, Yonghong Wan

Int J Mol Sci· February 2022

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Response to FEC Chemotherapy and Oncolytic HSV-1 Is Associated with Macrophage Polarization and Increased Expression of S100A8/A9 in Triple Negative Breast Cancer.
Alyssa Vito, Nader El-Sayes, Omar Salem, Yonghong Wan, Karen L Mossman

Cancers (Basel)· November 2021

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Immune checkpoint blockade in triple negative breast cancer influenced by B cells through myeloid-derived suppressor cells.
Alyssa Vito, Omar Salem, Nader El-Sayes, Ian P MacFawn, Ana L Portillo, Yonghong Wan

Commun Biol· July 2021

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Functional Analysis of Tumor-Infiltrating Myeloid Cells by Flow Cytometry and Adoptive Transfer.
Andrew Nguyen, Omar Salem, Yonghong Wan

J Vis Exp· March 2021

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A Transit Time-Resolved Microflow Cytometry-Based Agglutination Immunoassay for On-Site C-Reactive Protein Detection.
Jianxi Qu, Yushan Zhang, Mathieu Chenier, Chang-Qing Xu, Lan Chen, Yonghong Wan

Micromachines (Basel)· January 2021

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A rational relationship: Oncolytic virus vaccines as functional partners for adoptive T cell therapy.
Rebecca Burchett, Scott Walsh, Yonghong Wan, Jonathan L Bramson

Cytokine Growth Factor Rev· December 2020

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De novo necroptosis creates an inflammatory environment mediating tumor susceptibility to immune checkpoint inhibitors.
Samuel T Workenhe, Andrew Nguyen, David Bakhshinyan, Jiarun Wei, David N Hare, Yonghong Wan

Commun Biol· November 2020

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Enhanced immunotherapeutic profile of oncolytic virus-based cancer vaccination using cyclophosphamide preconditioning.
Jonathan G Pol, Matthew J Atherton, Kyle B Stephenson, Byram W Bridle, Samuel T Workenhe, Yonghong Wan

J Immunother Cancer· August 2020

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Ketogenesis-generated β-hydroxybutyrate is an epigenetic regulator of CD8 T-cell memory development.
Huafeng Zhang, Ke Tang, Jingwei Ma, Li Zhou, Jincheng Liu, Yonghong Wan

Nat Cell Biol· January 2020

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Endogenous T cells prevent tumor immune escape following adoptive T cell therapy.
Scott R Walsh, Boris Simovic, Lan Chen, Donald Bastin, Andrew Nguyen, Yonghong Wan

J Clin Invest· December 2019

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Development and applications of oncolytic Maraba virus vaccines.
Jonathan G Pol, Matthew J Atherton, Byram W Bridle, Kyle B Stephenson, Fabrice Le Boeuf, Yonghong Wan

Oncolytic Virother· November 2018

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Preclinical evaluation of a MAGE-A3 vaccination utilizing the oncolytic Maraba virus currently in first-in-human trials.
Jonathan G Pol, Sergio A Acuna, Beta Yadollahi, Nan Tang, Kyle B Stephenson, Yonghong Wan

Oncoimmunology· September 2018

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