Publications by authors named "Yoshio Hamada"

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Development of detection system for lead ions in mixture solutions using UV-Vis measurements with peptide immobilized microbeads.
Shuhei Yoshida, Koki Yoshida, Yoshio Hamada, Takaaki Tsuruoka, Kenji Usui

Sci Rep· January 2025

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De novo design of a nanopore for single-molecule detection that incorporates a β-hairpin peptide.
Keisuke Shimizu, Batsaikhan Mijiddorj, Masataka Usami, Ikuro Mizoguchi, Shuhei Yoshida, Yoshio Hamada

Nat Nanotechnol· January 2022

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Peptidomimetic Synthesis: Drug Discovery for Alzheimer's Disease.
Yoshio Hamada, Zyta M Ziora

Methods Mol Biol· January 2021

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Mass Spectrometry-Based Solid Phase Peptide Reaction Assay for Detecting Allergenicity Using an Immobilized Peptide-Conjugating Photo-Cleavable Linker.
Hiroshi Miyazaki, Yasutaka Samejima, Kazuya Iwata, Yuuki Minamino, Shinya Hikida, Yoshio Hamada

Int J Mol Sci· November 2020

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Development of a chromophore-solid phase peptide reaction assay (C-SPRA) for assessing skin sensitization in vitro.
Hiroshi Miyazaki, Yoshio Hamada, Hikaru Takaishi, Yuuki Minamino, Hidefumi Ikeda

Analyst· May 2020

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Peptides for Silica Precipitation: Amino Acid Sequences for Directing Mineralization.
Makoto Ozaki, Shungo Sakashita, Yoshio Hamada, Kenji Usui

Protein Pept Lett· February 2019

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Editorial: Organic-Inorganic Hybrid Materials and Their Applications.
Kin-Ya Tomizaki, Yoshio Hamada, Kenji Usui

Protein Pept Lett· November 2018

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DNA G-Wire Formation Using an Artificial Peptide is Controlled by Protease Activity.
Kenji Usui, Arisa Okada, Shungo Sakashita, Masayuki Shimooka, Takaaki Tsuruoka, Yoshio Hamada

Molecules· November 2017

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Recent progress in prodrug design strategies based on generally applicable modifications.
Yoshio Hamada

Bioorg Med Chem Lett· April 2017

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New directions for protease inhibitors directed drug discovery.
Yoshio Hamada, Yoshiaki Kiso

Biopolymers· November 2016

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Site-specific control of multiple mineralizations using a designed peptide and DNA.
Kenji Usui, Makoto Ozaki, Aoi Yamada, Yoshio Hamada, Takaaki Tsuruoka

Nanoscale· October 2016

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A novel N-terminal degradation reaction of peptides via N-amidination.
Yoshio Hamada

Bioorg Med Chem Lett· April 2016

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Novel prodrugs with a spontaneous cleavable guanidine moiety.
Yoshio Hamada

Bioorg Med Chem Lett· April 2016

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Novel β-amyloid aggregation inhibitors possessing a turn mimic.
Yoshio Hamada, Naoko Miyamoto, Yoshiaki Kiso

Bioorg Med Chem Lett· April 2015

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[Significance of quantum chemical interactions for medicinal science and design of β-secretase inhibitors].
Yoshio Hamada

Yakugaku Zasshi· April 2014

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Structure-activity relationship study of BACE1 inhibitors possessing a chelidonic or 2,6-pyridinedicarboxylic scaffold at the P(2) position.
Yoshio Hamada, Kenji Suzuki, Tomoya Nakanishi, Diganta Sarma, Hiroko Ohta

Bioorg Med Chem Lett· January 2014

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Novel BACE1 inhibitors with a non-acidic heterocycle at the P1' position.
Kenji Suzuki, Yoshio Hamada, Jeffrey-Tri Nguyen, Yoshiaki Kiso

Bioorg Med Chem· November 2013

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The transcriptional co-repressor TLE3 regulates development of trophoblast giant cells lining maternal blood spaces in the mouse placenta.
Malgorzata Gasperowicz, Cordula Surmann-Schmitt, Yoshio Hamada, Florian Otto, James C Cross

Dev Biol· October 2013

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Advances in the identification of β-secretase inhibitors.
Yoshio Hamada, Yoshiaki Kiso

Expert Opin Drug Discov· June 2013

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The application of bioisosteres in drug design for novel drug discovery: focusing on acid protease inhibitors.
Yoshio Hamada, Yoshiaki Kiso

Expert Opin Drug Discov· October 2012

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Novel BACE1 inhibitors possessing a 5-nitroisophthalic scaffold at the P2 position.
Yoshio Hamada, Tomoya Nakanishi, Kenji Suzuki, Ryoji Yamaguchi, Takashi Hamada

Bioorg Med Chem Lett· July 2012

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BACE1 Inhibitor Peptides: Can an Infinitely Small k cat Value Turn the Substrate of an Enzyme into Its Inhibitor?
Yoshio Hamada, Shoichi Ishiura, Yoshiaki Kiso

ACS Med Chem Lett· March 2012

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Tripeptidic BACE1 inhibitors devised by in-silico conformational structure-based design.
Yoshio Hamada, Harichandra D Tagad, Yoshinori Nishimura, Shoichi Ishiura, Yoshiaki Kiso

Bioorg Med Chem Lett· January 2012

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Structure-guided design and synthesis of P1' position 1-phenylcycloalkylamine-derived pentapeptidic BACE1 inhibitors.
Harichandra D Tagad, Yoshio Hamada, Jeffrey-Tri Nguyen, Koushi Hidaka, Takashi Hamada

Bioorg Med Chem· September 2011

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Tetrapeptides, as small-sized peptidic inhibitors; synthesis and their inhibitory activity against BACE1.
Taeko Kakizawa, Koushi Hidaka, Daisuke Hamada, Ryoji Yamaguchi, Tsuyoshi Uemura, Takashi Hamada, Yoshio Hamada

J Pept Sci· June 2010

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