Publications by authors named "Yoshiro Niitsu"

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ROS-Driven PKCζ Signaling as a Widely Involved Mechanism for Cancer Cell Motility and Metastasis.
Yasushi Sato, Maki Tanaka, Naoko Kitamura, Naoko Araki, Wataru Kurata, Yoshiro Niitsu

Cancer Sci· November 2025

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Implications of glutathione-S transferase P1 in MAPK signaling as a CRAF chaperone: In memory of Dr. Irving Listowsky.
Yoshiro Niitsu, Yasushi Sato, Tetsuji Takayama

Proc Jpn Acad Ser B Phys Biol Sci· March 2022

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Chemoprevention of pancreatic cancer by inhibition of glutathione-S transferase P1.
Takahiro Kogawa, Yasushi Sato, Rai Shimoyama, Wataru Kurata, Yasuyuki Tashiro, Yoshiro Niitsu

Invest New Drugs· December 2021

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Resolution of fibrosis by siRNA HSP47 in vitamin A-coupled liposomes induces regeneration of chronically injured livers.
Yasushi Sato, Akihiro Yoneda, Fumiko Shimizu, Miyuki Nishimura, Rai Shimoyama, Yoshiro Niitsu

J Gastroenterol Hepatol· December 2021

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A CRAF/glutathione-S-transferase P1 complex sustains autocrine growth of cancers with and mutations.
Yoshiro Niitsu, Yasushi Sato, Kunihiro Takanashi, Tsuyoshi Hayashi, Naoko Kubo-Birukawa

Proc Natl Acad Sci U S A· August 2020

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Treatment of pulmonary fibrosis with siRNA against a collagen-specific chaperone HSP47 in vitamin A-coupled liposomes.
Mitsuo Otsuka, Masanori Shiratori, Hirofumi Chiba, Koji Kuronuma, Yasushi Sato, Yoshiro Niitsu

Exp Lung Res· June 2018

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Vitamin A-coupled liposomes containing siRNA against HSP47 ameliorate skin fibrosis in chronic graft-versus-host disease.
Tomohiro Yamakawa, Hiroyuki Ohigashi, Daigo Hashimoto, Eiko Hayase, Shuichiro Takahashi, Yoshiro Niitsu

Blood· March 2018

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Involvement of Pancreatic Stellate Cells in Regeneration of Remnant Pancreas after Partial Pancreatectomy.
Shigenori Ota, Miyuki Nishimura, Yuya Murakami, Naoko Kubo Birukawa, Akihiro Yoneda, Yoshiro Niitsu

PLoS One· July 2017

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Panitumumab in combination with irinotecan plus S-1 (IRIS) as second-line therapy for metastatic colorectal cancer.
Toshi Takaoka, Tetsuo Kimura, Rai Shimoyama, Shunji Kawamoto, Kazuki Sakamoto, Yoshiro Niitsu

Cancer Chemother Pharmacol· August 2016

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Vitamin A and insulin are required for the maintenance of hepatic stellate cell quiescence.
Akihiro Yoneda, Kaori Sakai-Sawada, Yoshiro Niitsu, Yasuaki Tamura

Exp Cell Res· February 2016

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Activated hepatic stellate cells are dependent on self-collagen, cleaved by membrane type 1 matrix metalloproteinase for their growth.
Naoko Kubo Birukawa, Kazuyuki Murase, Yasushi Sato, Akemi Kosaka, Akihiro Yoneda, Yoshiro Niitsu

J Biol Chem· July 2014

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Treatment of pancreatic fibrosis with siRNA against a collagen-specific chaperone in vitamin A-coupled liposomes.
Hirotoshi Ishiwatari, Yasushi Sato, Kazuyuki Murase, Akihiro Yoneda, Ryosuke Fujita, Yoshiro Niitsu

Gut· September 2013

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Efficacy and safety of micafungin as an empirical antifungal therapy for suspected fungal infection in neutropenic patients with hematological disorders.
Minoru Yoshida, Kazuo Tamura, Masahiro Imamura, Yoshiro Niitsu, Takeshi Sasaki

Ann Hematol· March 2012

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Randomized double-blind trial of sulindac and etodolac to eradicate aberrant crypt foci and to prevent sporadic colorectal polyps.
Tetsuji Takayama, Hiroyuki Nagashima, Masahiro Maeda, Shuichi Nojiri, Michiaki Hirayama, Yoshiro Niitsu

Clin Cancer Res· June 2011

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Intravenous administration of auto serum-expanded autologous mesenchymal stem cells in stroke.
Osamu Honmou, Kiyohiro Houkin, Takuya Matsunaga, Yoshiro Niitsu, Sumio Ishiai

Brain· June 2011

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Phase II study of S-1, docetaxel and cisplatin combination chemotherapy in patients with unresectable metastatic gastric cancer.
Yasushi Sato, Tetsuji Takayama, Tamotsu Sagawa, Yasuo Takahashi, Hiroyuki Ohnuma, Yoshiro Niitsu

Cancer Chemother Pharmacol· September 2010

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Pure red cell aplasia associated with Good's syndrome accompanied by decreased stem cell factor production in the bone marrow.
Kageaki Kuribayashi, Akihito Fujimi, Masayoshi Kobune, Rishu Takimoto, Shohei Kikuchi, Yoshiro Niitsu

Intern Med· May 2010

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Suppressive effect of sulindac on branch duct-intraductal papillary mucinous neoplasms.
Tsuyoshi Hayashi, Hirotoshi Ishiwatari, Hideyuki Ihara, Yutaka Kawano, Koichi Takada, Yoshiro Niitsu

J Gastroenterol· January 2010

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Interleukin-2 gene transfer potentiates the alpha-galactosylceramide-stimulated antitumor effect by the induction of TRAIL in NKT and NK cells in mouse models of subcutaneous and metastatic carcinoma.
Yoshiki Nishihori, Kazunori Kato, Maki Tanaka, Tetsuro Okamoto, Seiya Hagiwara, Yoshiro Niitsu

Cancer Biol Ther· September 2009

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Drug resistance is dramatically restored by hedgehog inhibitors in CD34+ leukemic cells.
Masayoshi Kobune, Rishu Takimoto, Kazuyuki Murase, Satoshi Iyama, Tsutomu Sato, Yoshiro Niitsu

Cancer Sci· May 2009

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[Effective CDDP arterial infusion with DSM for liver metastasis of malignant melanoma complicating DIC due to intratumoral hemorrhage--a case report].
Kohichi Takada, Junji Kato, Yutaka Kawano, Sho Takahashi, Tsuyoshi Hayashi, Yoshiro Niitsu

Gan To Kagaku Ryoho· October 2008

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Treatment of hepatocellular carcinoma by AdAFPep/rep, AdAFPep/p53, and 5-fluorouracil in mice.
Tamotsu Sagawa, Yasuyuki Yamada, Minoru Takahashi, Yasushi Sato, Masayoshi Kobune, Yoshiro Niitsu

Hepatology· September 2008

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[A case of hepatosplenic gammadelta T-cell lymphoma associated hemophagocytic syndrome].
Satoshi Iyama, Takuya Matsunaga, Tsutomu Sato, Yasushi Sato, Tamotsu Sagawa, Yoshiro Niitsu

Gan To Kagaku Ryoho· September 2008

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[Cyclic thrombocytopenia complicated with Sjögren syndrome and the mechanism of periodic platelet count fluctuation].
Naofumi Yamauchi, Hirohito Muramatsu, Hidetoshi Inomata, Takaaki Numata, Eri Nozawa, Yoshiro Niitsu

Rinsho Ketsueki· August 2008

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Japanese epidemiological survey with consensus statement on Japanese guidelines for treatment of iron overload in bone marrow failure syndromes.
Takahiro Suzuki, Masao Tomonaga, Yasushi Miyazaki, Shinji Nakao, Kazuma Ohyashiki, Yoshiro Niitsu

Int J Hematol· July 2008

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