Publications by authors named "Yosuke Funato"

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AI-driven mechanistic analysis of conformational dynamics in CNNM/CorC Mg transporters.
Jie Ma, Xingyu Song, Yosuke Funato, Xinyu Teng, Yichen Huang

Structure· January 2025

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Development of a high-throughput screening system targeting the protein-protein interactions between PRL and CNNM.
Yosuke Funato, Mai Mimura, Kazuto Nunomura, Bangzhong Lin, Shintarou Fujii

Sci Rep· October 2024

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Intestinal Mg accumulation induced by cnnm mutations decreases the body size by suppressing TORC2 signaling in Caenorhabditis elegans.
Osamu Hashizume, Tomofumi Kawabe, Yosuke Funato, Hiroaki Miki

Dev Biol· May 2024

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Phosphatase-independent role of phosphatase of regenerating liver in cancer progression.
Yosuke Funato, Osamu Hashizume, Hiroaki Miki

Cancer Sci· January 2023

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PRL stimulates mitotic errors by suppressing kinetochore-localized activation of AMPK during mitosis.
Kajung Ryu, Atsushi Yoshida, Yosuke Funato, Daisuke Yamazaki, Hiroaki Miki

Cell Struct Funct· December 2022

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The emerging roles and therapeutic potential of cyclin M/CorC family of Mg transporters.
Yosuke Funato, Hiroaki Miki

J Pharmacol Sci· January 2022

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A novel role for PRL in regulating epithelial cell density by inducing apoptosis at confluence.
Sweksha Lohani, Yosuke Funato, Yuki Akieda, Kiyohito Mizutani, Yoshimi Takai

J Cell Sci· January 2022

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Importance of the renal ion channel TRPM6 in the circadian secretion of renin to raise blood pressure.
Yosuke Funato, Daisuke Yamazaki, Daisuke Okuzaki, Nobuhiko Yamamoto, Hiroaki Miki

Nat Commun· June 2021

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Identification and mechanistic analysis of an inhibitor of the CorC Mg transporter.
Yichen Huang, Kaijie Mu, Xinyu Teng, Yimeng Zhao, Yosuke Funato

iScience· April 2021

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Structural basis for the Mg recognition and regulation of the CorC Mg transporter.
Yichen Huang, Fei Jin, Yosuke Funato, Zhijian Xu, Weiliang Zhu

Sci Adv· February 2021

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Role of adenomatous polyposis coli in proliferation and differentiation of colon epithelial cells in organoid culture.
Daisuke Yamazaki, Osamu Hashizume, Shiho Taniguchi, Yosuke Funato, Hiroaki Miki

Sci Rep· February 2021

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The Oncogenic PRL Protein Causes Acid Addiction of Cells by Stimulating Lysosomal Exocytosis.
Yosuke Funato, Atsushi Yoshida, Yusuke Hirata, Osamu Hashizume, Daisuke Yamazaki

Dev Cell· November 2020

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Magnesium efflux from Drosophila Kenyon cells is critical for normal and diet-enhanced long-term memory.
Yanying Wu, Yosuke Funato, Eleonora Meschi, Kristijan D Jovanoski, Hiroaki Miki

Elife· November 2020

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PRL3 pseudophosphatase activity is necessary and sufficient to promote metastatic growth.
Guennadi Kozlov, Yosuke Funato, Yu Seby Chen, Zhidian Zhang, Katalin Illes

J Biol Chem· August 2020

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Excessive Mg Impairs Intestinal Homeostasis by Enhanced Production of Adenosine Triphosphate and Reactive Oxygen Species.
Osamu Hashizume, Yosuke Funato, Daisuke Yamazaki, Hiroaki Miki

Antioxid Redox Signal· July 2020

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Cnnm4 deficiency suppresses Ca signaling and promotes cell proliferation in the colon epithelia.
Daisuke Yamazaki, Ayaka Hasegawa, Yosuke Funato, Ha Nam Tran, Masayuki X Mori

Oncogene· May 2019

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Phosphatase of regenerating liver sensitizes MET to functional activation by hepatocyte growth factor.
Takuya Kojima, Yosuke Funato, Hiroaki Miki

Biochem J· May 2019

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Molecular function and biological importance of CNNM family Mg2+ transporters.
Yosuke Funato, Hiroaki Miki

J Biochem· March 2019

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The cyclic nucleotide-binding homology domain of the integral membrane protein CNNM mediates dimerization and is required for Mg efflux activity.
Yu Seby Chen, Guennadi Kozlov, Rayan Fakih, Yosuke Funato, Hiroaki Miki

J Biol Chem· December 2018

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CrossTalk proposal: CNNM proteins are Na /Mg exchangers playing a central role in transepithelial Mg (re)absorption.
Yosuke Funato, Kazuharu Furutani, Yoshihisa Kurachi, Hiroaki Miki

J Physiol· March 2018

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Rebuttal from Yosuke Funato, Kazuharu Furutani, Yoshihisa Kurachi and Hiroaki Miki.
Yosuke Funato, Kazuharu Furutani, Yoshihisa Kurachi, Hiroaki Miki

J Physiol· March 2018

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Phosphatase of regenerating liver maintains cellular magnesium homeostasis.
Atsushi Yoshida, Yosuke Funato, Hiroaki Miki

Biochem J· March 2018

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Visualization of long-term Mg dynamics in apoptotic cells using a novel targetable fluorescent probe.
Yusuke Matsui, Yosuke Funato, Hiromi Imamura, Hiroaki Miki, Shin Mizukami

Chem Sci· December 2017

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Renal function of cyclin M2 Mg2+ transporter maintains blood pressure.
Yosuke Funato, Daisuke Yamazaki, Hiroaki Miki

J Hypertens· March 2017

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Phosphocysteine in the PRL-CNNM pathway mediates magnesium homeostasis.
Irina Gulerez, Yosuke Funato, Howie Wu, Meng Yang, Guennadi Kozlov

EMBO Rep· December 2016

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