Publications by authors named "Yosuke Isobe"

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Eosinophils and pleural macrophages counter regulate IL-33-elicited airway inflammation via the 12/15-lipoxygenase pathway.
Emi Ito, Reika Hayashizaki, Takuro Hosaka, Tsuyoshi Yamane, Jun Miyata, Yosuke Isobe

Front Immunol· May 2025

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12/15-Lipoxygenase-Derived Electrophilic Lipid Modifications in Phagocytic Macrophages.
Kaiyuan Deng, Yosuke Isobe, Kazuya Tsumagari, Taiga Kato, Hiroyuki Arai

ACS Chem Biol· February 2025

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Spatiotemporally distinct roles of cyclooxygenase-1 and cyclooxygenase-2 at fetomaternal interface in mice.
Shizu Aikawa, Mitsunori Matsuo, Shun Akaeda, Yukihiko Sugimoto, Makoto Arita, Yosuke Isobe

JCI Insight· August 2024

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Exploring protein lipidation by mass spectrometry-based proteomics.
Kazuya Tsumagari, Yosuke Isobe, Koshi Imami, Makoto Arita

J Biochem· March 2024

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Application of Liquid-Liquid Extraction for N-terminal Myristoylation Proteomics.
Kazuya Tsumagari, Yosuke Isobe, Yasushi Ishihama, Jun Seita, Makoto Arita

Mol Cell Proteomics· December 2023

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Long chain acyl-CoA synthetase 6 facilitates the local distribution of di-docosahexaenoic acid- and ultra-long-chain-PUFA-containing phospholipids in the retina to support normal visual function in mice.
Sayoko Kuroha, Yusaku Katada, Yosuke Isobe, Haruki Uchino, Kyosuke Shishikura

FASEB J· September 2023

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Chemoproteomic Profiling Reveals that Anticancer Natural Product Dankastatin B Covalently Targets Mitochondrial VDAC3.
Bridget P Belcher, Paulo A Machicao, Binqi Tong, Emily Ho, Julia Friedli, Yosuke Isobe

Chembiochem· July 2023

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Gut microbiota-derived lipid metabolites facilitate regulatory T cell differentiation.
Hiroaki Shiratori, Hiroyuki Oguchi, Yosuke Isobe, Kyu-Ho Han, Akira Sen

Sci Rep· June 2023

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Enzymatically-epoxidized docosahexaenoic acid, 19,20-EpDPE, suppresses hepatic crown-like structure formation and nonalcoholic steatohepatitis fibrosis through GPR120.
Hidenori Aoki, Yosuke Isobe, Mio Yoshida, Jing X Kang, Masashi Maekawa

Biochim Biophys Acta Mol Cell Biol Lipids· March 2023

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Chemoproteomic Profiling Reveals that Anti-Cancer Natural Product Dankastatin B Covalently Targets Mitochondrial VDAC3.
Bridget P Belcher, Paulo A Machicao, Binqi Tong, Emily Ho, Julia Friedli, Yosuke Isobe

bioRxiv· February 2023

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Genetic deletion of Cyp4f18 disrupts the omega-3 epoxidation pathway and results in psoriasis-like dermatitis.
Mio Yoshida, Tomoaki Ishihara, Yosuke Isobe, Makoto Arita

FASEB J· December 2022

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Sterol O-Acyltransferase Inhibition Ameliorates High-Fat Diet-Induced Renal Fibrosis and Tertiary Lymphoid Tissue Maturation after Ischemic Reperfusion Injury.
Yuki Ariyasu, Yuki Sato, Yosuke Isobe, Keisuke Taniguchi, Motoko Yanagita

Int J Mol Sci· December 2022

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Manumycin polyketides act as molecular glues between UBR7 and P53.
Yosuke Isobe, Mikiko Okumura, Lynn M McGregor, Scott M Brittain, Michael D Jones

Nat Chem Biol· November 2020

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Eosinophils promote corneal wound healing via the 12/15-lipoxygenase pathway.
Mamoru Ogawa, Tomoaki Ishihara, Yosuke Isobe, Taiga Kato, Keiji Kuba

FASEB J· September 2020

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Maternal gut microbiota in pregnancy influences offspring metabolic phenotype in mice.
Ikuo Kimura, Junki Miyamoto, Ryuji Ohue-Kitano, Keita Watanabe, Takahiro Yamada, Yosuke Isobe

Science· February 2020

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The 17,18-epoxyeicosatetraenoic acid-G protein-coupled receptor 40 axis ameliorates contact hypersensitivity by inhibiting neutrophil mobility in mice and cynomolgus macaques.
Takahiro Nagatake, Yumiko Shiogama, Asuka Inoue, Junichi Kikuta, Tetsuya Honda, Yosuke Isobe

J Allergy Clin Immunol· August 2018

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Comprehensive analysis of the mouse cytochrome P450 family responsible for omega-3 epoxidation of eicosapentaenoic acid.
Yosuke Isobe, Mai Itagaki, Yuko Ito, Satoko Naoe, Kotoe Kojima

Sci Rep· May 2018

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Identification of Protein Targets of 12/15-Lipoxygenase-Derived Lipid Electrophiles in Mouse Peritoneal Macrophages Using Omega-Alkynyl Fatty Acid.
Yosuke Isobe, Yusuke Kawashima, Tomoaki Ishihara, Kenji Watanabe, Osamu Ohara

ACS Chem Biol· April 2018

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Reduction of lipid accumulation rescues Bietti's crystalline dystrophy phenotypes.
Masayuki Hata, Hanako O Ikeda, Sachiko Iwai, Yuto Iida, Norimoto Gotoh, Yosuke Isobe

Proc Natl Acad Sci U S A· April 2018

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Comprehensive analyses of oxidized phospholipids using a measured MS/MS spectra library.
Ryohei Aoyagi, Kazutaka Ikeda, Yosuke Isobe, Makoto Arita

J Lipid Res· November 2017

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Modeling of lung's electrical impedance using fractional calculus for analysis of heat generation during RF-ablation.
Nozomu Yamazaki, Yo Kobayashi, Hayato Kikuchi, Yosuke Isobe, XiaoWei Lu

Annu Int Conf IEEE Eng Med Biol Soc· October 2015

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Total Synthesis of Four Stereoisomers of (4Z,7Z,10Z,12E,16Z,18E)-14,20-Dihydroxy-4,7,10,12,16,18-docosahexaenoic Acid and Their Anti-inflammatory Activities.
Tomomi Goto, Daisuke Urabe, Koji Masuda, Yosuke Isobe, Makoto Arita

J Org Chem· August 2015

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Method for estimating the temperature distribution associated with the vessel cooling effect in radio frequency ablation.
Xiaowei Lu, Hayato Kikuchi, Kazumasa Hirooka, Yosuke Isobe, Hiroki Watanabe

Annu Int Conf IEEE Eng Med Biol Soc· August 2015

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Identification of novel omega-3 fatty acid-derived bioactive metabolites based on a targeted lipidomics approach.
Yosuke Isobe, Makoto Arita

J Clin Biochem Nutr· September 2014

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18-HEPE, an n-3 fatty acid metabolite released by macrophages, prevents pressure overload-induced maladaptive cardiac remodeling.
Jin Endo, Motoaki Sano, Yosuke Isobe, Keiichi Fukuda, Jing X Kang

J Exp Med· July 2014

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