Publications by authors named "Yosuke Ohtake"

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Glial senescence enhances α-synuclein pathology owing to its insufficient clearance caused by autophagy dysfunction.
Bin Hong, Yosuke Ohtake, Takahide Itokazu, Toshihide Yamashita

Cell Death Discov· January 2024

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Immunotherapies in Huntington's disease and α-Synucleinopathies.
Oluwaseun Fatoba, Yosuke Ohtake, Takahide Itokazu, Toshihide Yamashita

Front Immunol· March 2021

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Upregulating Lin28a Promotes Axon Regeneration in Adult Mice with Optic Nerve and Spinal Cord Injury.
Fatima M Nathan, Yosuke Ohtake, Shuo Wang, Xinpei Jiang, Armin Sami

Mol Ther· August 2020

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Promoting Axon Regeneration in Adult CNS by Targeting Liver Kinase B1.
Yosuke Ohtake, Armin Sami, Xinpei Jiang, Makoto Horiuchi, Kieran Slattery

Mol Ther· January 2019

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S6K/p70S6K1 protects against tau-mediated neurodegeneration by decreasing the level of tau phosphorylated at Ser262 in a Drosophila model of tauopathy.
Tomoki Chiku, Motoki Hayashishita, Taro Saito, Mikiko Oka, Kanako Shinno, Yosuke Ohtake

Neurobiol Aging· November 2018

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ER Stress and Disease: Toward Prevention and Treatment.
Masayuki Kaneko, Kazunori Imaizumi, Atsushi Saito, Soshi Kanemoto, Rie Asada, Yosuke Ohtake

Biol Pharm Bull· May 2018

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Diverse functions of protein tyrosine phosphatase σ in the nervous and immune systems.
Yosuke Ohtake, Atsushi Saito, Shuxin Li

Exp Neurol· April 2018

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Axonal Activation of the Unfolded Protein Response Promotes Axonal Regeneration Following Peripheral Nerve Injury.
Yosuke Ohtake, Koji Matsuhisa, Masayuki Kaneko, Soshi Kanemoto, Rie Asada

Neuroscience· April 2018

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Sec16A, a key protein in COPII vesicle formation, regulates the stability and localization of the novel ubiquitin ligase RNF183.
Yan Wu, Xiao Peng Guo, Soshi Kanemoto, Yujiro Maeoka, Atsushi Saito, Yosuke Ohtake

PLoS One· February 2018

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Neuronal activity-dependent local activation of dendritic unfolded protein response promotes expression of brain-derived neurotrophic factor in cell soma.
Atsushi Saito, Longjie Cai, Koji Matsuhisa, Yosuke Ohtake, Masayuki Kaneko

J Neurochem· January 2018

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Ca2+/calmodulin-dependent protein kinase II promotes neurodegeneration caused by tau phosphorylated at Ser262/356 in a transgenic Drosophila model of tauopathy.
Mikiko Oka, Naoki Fujisaki, Akiko Maruko-Otake, Yosuke Ohtake, Sawako Shimizu

J Biochem· November 2017

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Protein tyrosine phosphatase σ regulates autoimmune encephalomyelitis development.
Yosuke Ohtake, Weimin Kong, Rashad Hussain, Makoto Horiuchi, Michel L Tremblay

Brain Behav Immun· October 2017

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Two PTP receptors mediate CSPG inhibition by convergent and divergent signaling pathways in neurons.
Yosuke Ohtake, Daniella Wong, P M Abdul-Muneer, Michael E Selzer, Shuxin Li

Sci Rep· November 2016

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Tau phosphorylation at Alzheimer's disease-related Ser356 contributes to tau stabilization when PAR-1/MARK activity is elevated.
Kanae Ando, Mikiko Oka, Yosuke Ohtake, Motoki Hayashishita, Sawako Shimizu

Biochem Biophys Res Commun· September 2016

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Reactive astrocyte scar and axon regeneration: suppressor or facilitator?
Yosuke Ohtake, George M Smith, Shuxin Li

Neural Regen Res· July 2016

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Cre-inducible human CD59 mediates rapid cell ablation after intermedilysin administration.
Dechun Feng, Shen Dai, Fengming Liu, Yosuke Ohtake, Zhou Zhou

J Clin Invest· June 2016

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Stabilization of Microtubule-Unbound Tau via Tau Phosphorylation at Ser262/356 by Par-1/MARK Contributes to Augmentation of AD-Related Phosphorylation and Aβ42-Induced Tau Toxicity.
Kanae Ando, Akiko Maruko-Otake, Yosuke Ohtake, Motoki Hayashishita, Michiko Sekiya

PLoS Genet· March 2016

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Molecular mechanisms of scar-sourced axon growth inhibitors.
Yosuke Ohtake, Shuxin Li

Brain Res· September 2015

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PTEN inhibition and axon regeneration and neural repair.
Yosuke Ohtake, Umar Hayat, Shuxin Li

Neural Regen Res· September 2015

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Farnesoid X receptor knockdown provides significant growth inhibition in hepatocellular carcinoma cells while it does not interfere with the proliferation of primary human hepatocyte-derived cells.
Tomofumi Fujino, Akiko Maruko-Ohtake, Yosuke Ohtake, Tomonori Kobayashi, Ken Ando

J Toxicol Sci· August 2015

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Role of CSPG receptor LAR phosphatase in restricting axon regeneration after CNS injury.
Bin Xu, Dongsun Park, Yosuke Ohtake, Hui Li, Umar Hayat

Neurobiol Dis· January 2015

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The effect of systemic PTEN antagonist peptides on axon growth and functional recovery after spinal cord injury.
Yosuke Ohtake, Dongsun Park, P M Abdul Muneer, Hui Li, Bin Xu

Biomaterials· May 2014

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Loss of axonal mitochondria promotes tau-mediated neurodegeneration and Alzheimer's disease-related tau phosphorylation via PAR-1.
Kanae Iijima-Ando, Michiko Sekiya, Akiko Maruko-Otake, Yosuke Ohtake, Emiko Suzuki

PLoS Genet· January 2013

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Critical role of farnesoid X receptor for hepatocellular carcinoma cell proliferation.
Tomofumi Fujino, Airi Takeuchi, Akiko Maruko-Ohtake, Yosuke Ohtake, Junichi Satoh

J Biochem· December 2012

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Effect of aging on norepinephrine-related proliferative response in primary cultured periportal and perivenous hepatocytes.
Tomonori Kobayashi, Yohei Saito, Yosuke Ohtake, Akiko Maruko, Yumi Yamamoto

Am J Physiol Gastrointest Liver Physiol· October 2012

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