Publications by authors named "Youhai Chen"

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DR5 CAR-NK cells demonstrate superior scalability and potent antitumor activity with favorable safety.
Qian Chen, Meng Xia, Mengyan Tang, Maoxuan Liu, Dehong Yan, Weihong Chen, Youhai H Chen

Mol Ther· December 2025

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Cancer immunotherapy by silencing transcription factor c-Rel using peptide-based nanoparticles.
Shuyao Lang, Yuxuan Zhu, Zibin Tan, Yu Zhang, Ruijing Liang, Youhai H Chen

Front Immunol· May 2025

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Akt2 deficiency impairs Th17 differentiation, augments Th2 differentiation, and alters the peripheral response to immunization.
Lauren B Banks, Tammarah Sklarz, Mercy Gohil, Claire O'Leary, Edward M Behrens, Youhai H Chen

bioRxiv· June 2024

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Small-Molecule Inhibitors of TIPE3 Protein Identified through Deep Learning Suppress Cancer Cell Growth In Vitro.
Xiaodie Chen, Zhen Lu, Jin Xiao, Wei Xia, Yi Pan, Youhai H Chen

Cells· April 2024

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Author Correction: Stiff matrix induces exosome secretion to promote tumour growth.
Bin Wu, Di-Ao Liu, Lei Guan, Phyoe Kyawe Myint, LiKang Chin, Youhai H Chen

Nat Cell Biol· March 2024

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TIPE proteins control directed migration of human T cells by directing GPCR and lipid second messenger signaling.
Jiyeon Yu, Ali Zamani, Jason R Goldsmith, Zienab Etwebi, Chin Nien Lee, Youhai H Chen

J Leukoc Biol· February 2024

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Epithelial TIPE1 Protein Guards against Colitis by Inhibiting TNF-α-Mediated Inflammation.
Yunwei Lou, Shan Jiang, Miaomiao Song, Han Wang, Meijuan Han, Youhai H Chen

J Immunol· September 2023

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Monocytes in Tumorigenesis and Tumor Immunotherapy.
Xiaodie Chen, Yunqing Li, Houjun Xia, Youhai H Chen

Cells· June 2023

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Apoptotic cell death in disease-Current understanding of the NCCD 2023.
Ilio Vitale, Federico Pietrocola, Emma Guilbaud, Stuart A Aaronson, John M Abrams, Guo-Qiang Chen, Quan Chen, Youhai H Chen, Emily H Cheng, Jochen H M Prehn

Cell Death Differ· May 2023

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Stiff matrix induces exosome secretion to promote tumour growth.
Bin Wu, Di-Ao Liu, Lei Guan, Phyoe Kyawe Myint, LiKang Chin, Youhai H Chen

Nat Cell Biol· March 2023

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How sugar instigates macrophages to be evils in tumor.
Houjun Xia, Youhai H Chen

Cell Mol Immunol· December 2022

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Inhibition of c-Rel expression in myeloid and lymphoid cells with distearoyl -phosphatidylserine (DSPS) liposomal nanoparticles encapsulating therapeutic siRNA.
Christian Bressy, Ali Zemani, Shreya Goyal, Davit Jishkariani, Chin Nien Lee, Youhai H Chen

PLoS One· December 2022

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CAR-Macrophages and CAR-T Cells Synergistically Kill Tumor Cells In Vitro.
Maoxuan Liu, Junchen Liu, Ziwei Liang, Kun Dai, Jiangyu Gan, Youhai H Chen

Cells· November 2022

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Dietary diversity is associated with nutrient adequacy, blood biomarkers and anthropometric status among preschool children in poor ethnic minority area of Northwest China.
Binshuo Hu, Shihua Tang, Zhuo Wang, Youhai Chen, Xiaohui Chen

Front Nutr· November 2022

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c-Rel-dependent monocytes are potent immune suppressor cells in cancer.
Ting Li, Mayassa J Bou-Dargham, Norman Fultang, Xinyuan Li, Warren S Pear, Youhai H Chen

J Leukoc Biol· October 2022

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Peritoneal resident macrophages in tumor metastasis and immunotherapy.
Yu Zhang, Dongyun Ouyang, Youhai H Chen, Houjun Xia

Front Cell Dev Biol· August 2022

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HRS phosphorylation drives immunosuppressive exosome secretion and restricts CD8 T-cell infiltration into tumors.
Lei Guan, Bin Wu, Ting Li, Lynn A Beer, Gaurav Sharma, Fangping Chen, Youhai H Chen

Nat Commun· July 2022

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Alteration in Gut Microbiota Associated with Zinc Deficiency in School-Age Children.
Xiaohui Chen, Yu Jiang, Zhuo Wang, Youhai Chen, Shihua Tang

Nutrients· July 2022

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TIPE2 Promotes Tumor Initiation But Inhibits Tumor Progression in Murine Colitis-Associated Colon Cancer.
Zienab Etwebi, Jason R Goldsmith, Mayassa Bou-Dargham, Yuhua Tian, Ryan Hood, Youhai H Chen

Inflamm Bowel Dis· May 2022

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TNFAIP8 protein functions as a tumor suppressor in inflammation-associated colorectal tumorigenesis.
Yunwei Lou, Xueqin Tian, Chen Sun, Miaomiao Song, Meijuan Han, Youhai H Chen

Cell Death Dis· April 2022

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Tumor Necrosis Factor-α-Induced Protein 8-Like 2 Fosters Tumor-Associated Microbiota to Promote the Development of Colorectal Cancer.
Yunwei Lou, Miaomiao Song, Meijuan Han, Jiateng Zhong, Xueqin Tian, Youhai H Chen

Cancer Immunol Res· March 2022

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TIPE polarity proteins are required for mucosal deployment of T lymphocytes and mucosal defense against bacterial infection.
Mingyue Li, Mayassa J Bou-Dargham, Jiyeon Yu, Zienab Etwebi, Honghong Sun, Youhai H Chen

Mol Biomed· December 2021

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Decoupling tumor cell metastasis from growth by cellular pilot protein TNFAIP8.
Mingyue Li, Xinyuan Li, Jason R Goldsmith, Songlin Shi, Li Zhang, Youhai H Chen

Oncogene· November 2021

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An Integrated Deep Learning and Molecular Dynamics Simulation-Based Screening Pipeline Identifies Inhibitors of a New Cancer Drug Target TIPE2.
Haiping Zhang, Junxin Li, Konda Mani Saravanan, Hao Wu, Zhichao Wang, Youhai H Chen

Front Pharmacol· November 2021

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Dietary Diversity and Nutrient Intake of Han and Dongxiang Smallholder Farmers in Poverty Areas of Northwest China.
Zhuo Wang, Youhai Chen, Shihua Tang, Siqi Chen, Shaoqing Gong

Nutrients· October 2021

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