Publications by authors named "Youjun Chen"

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Physiologically Based Pharmacokinetic/Pharmacodynamic Model for Secukinumab: Dose Exploration in Pediatric Patients with Plaque Psoriasis.
Liu Zhiwei, Wang Wenhui, Chen Tao, Li Yiming, Chen Youjun

J Clin Pharmacol· November 2025

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Cardiotropic AAV gene therapy for heart failure: a phase 1 trial.
Timothy D Henry, Eugene S Chung, Monica Alvisi, Ferzin Sethna, David R Murray, Youjun Chen

Nat Med· November 2025

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Physiologically based pharmacokinetic integrated models for lamotrigine to evaluate drug exposure and optimize dosage during pregnancy, foetal period, postpartum period, and in breastfed neonates.
Zhiwei Liu, Yiming Li, Youjun Chen, Saiya Li, Yating Wu

Br J Clin Pharmacol· November 2025

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Physiologically based pharmacokinetic coupled model of zonisamide to predict the exposure and dose exploration in maternal, fetal, and neonatal populations during pregnancy and postpartum.
Yiming Li, Zhiwei Liu, Youjun Chen, Wenhui Wang, Tao Chen

J Pharm Sci· September 2025

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Drug-Drug Interactions and Combination Therapy Strategies of Amiodarone With Digoxin, Rivaroxaban, and Phenytoin Assessed by Physiologically Based Pharmacokinetic Modeling.
Youjun Chen, Zhiwei Liu, Yiming Li, Wenhui Wang, Tao Chen

Pharmacotherapy· September 2025

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Genetic diversity analysis of phenotypic and agronomic traits in oat germplasm resources.
Yan Zhao, Jiaqi Fang, René Gislum, Baowen Zhao, Zhiming Zhong, Youjun Chen

Front Plant Sci· September 2025

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Modest Experimental Warming Reduces Species Diversity and Biomass of Arthropods in a Tibetan Alpine Meadow.
Xiaoli Hu, Xinwei Wu, Shuang Xiang, Youjun Chen, Lin Jiang

Glob Chang Biol· June 2025

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Photosynthetic performance and carbon metabolism in the ear organs of oats under drought stress.
Jiaqi Fang, Yuan Zhan, Baowen Zhao, Yan Zhao, Youjun Chen

Front Plant Sci· January 2025

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The antidepressants and sexual dysfunction: a pharmacovigilance-pharmacodynamic study of the FDA adverse event reporting system.
Yu Cheng, Youjun Chen, Xue Zhao, Fan Mou, Yingting Tan

Expert Opin Drug Saf· December 2024

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Physiologically based pharmacokinetic model of brivaracetam to predict the exposure and dose exploration in hepatic impairment and elderly populations.
Yiming Li, Wenxin Shao, Xingwen Wang, Kuo Geng, Wenhui Wang, Youjun Chen

J Pharm Sci· November 2024

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Physiologically Based Pharmacokinetic Modeling to Assess Ritonavir-Digoxin Interactions and Recommendations for Co-Administration Regimens.
Youjun Chen, Wenxin Shao, Xingwen Wang, Kuo Geng, Wenhui Wang

Pharm Res· November 2024

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Corrigendum: Microbiome and response surface methodology analyses reveal as the core bacteria responsible for aerobic spoilage of corn silage () in hot and humid areas.
Rui Bai, Haiping Li, Shiyong Chen, Xianjun Yuan, Youjun Chen

Front Microbiol· November 2024

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Physiologically based pharmacokinetic models for predicting lamotrigine exposure and dose optimization in pediatric patients receiving combination therapy with carbamazepine or valproic acid.
Zhiwei Liu, Wenxin Shao, Xingwen Wang, Kuo Geng, Wenhui Wang, Youjun Chen

Pharmacotherapy· September 2024

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Comparative physiological and transcriptomic analyses reveal genotype specific response to drought stress in Siberian wildrye (Elymus sibiricus).
Yongping An, Qian Wang, Yannong Cui, Xin Liu, Ping Wang, Youjun Chen

Sci Rep· September 2024

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Microbiome and response surface methodology analyses reveal as the core bacteria responsible for aerobic spoilage of corn silage () in hot and humid areas.
Rui Bai, Haiping Li, Shiyong Chen, Xianjun Yuan, Youjun Chen

Front Microbiol· September 2024

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Exploring Evolutionary Pathways and Abiotic Stress Responses through Genome-Wide Identification and Analysis of the Alternative Oxidase (AOX) Gene Family in Common Oat ().
Boyang Liu, Zecheng Zhang, Jinghan Peng, Haipeng Mou, Zhaoting Wang, Youjun Chen

Int J Mol Sci· August 2024

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The atypical antipsychotics and sexual dysfunction: a pharmacovigilance-pharmacodynamic study.
Yu Cheng, Youjun Chen, Xue Zhao, Fan Mou, Wanying Wang

Front Pharmacol· July 2024

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RNA-binding deficient TDP-43 drives cognitive decline in a mouse model of TDP-43 proteinopathy.
Julie C Necarsulmer, Jeremy M Simon, Baggio A Evangelista, Youjun Chen, Xu Tian

Elife· October 2023

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Transcriptomics integrated with metabolomics provides a new strategy for mining key genes in response to low temperature stress in Helictotrichon virescens.
Mingjun Cheng, Junjun Zheng, Kuoshu Cui, Xuan Luo, Tao Yang, Shiyong Chen, Youjun Chen

Int J Biol Macromol· July 2023

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Activity-dependent tau cleavage by caspase-3 promotes neuronal dysfunction and synaptotoxicity.
Carli K Opland, Miles R Bryan, Braxton Harris, Jake McGillion-Moore, Xu Tian, Youjun Chen

iScience· June 2023

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Genome-wide identification and characterization of abiotic stress responsive GRAS family genes in oat ().
Jing Pan, Qingping Zhou, Hui Wang, Youjun Chen, Zhiqiang Wang

PeerJ· May 2023

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Response characteristics of root to moisture change at seedling stage of .
Xueyao Chen, Youjun Chen, Wei Zhang, Wenlu Zhang, Hui Wang

Front Plant Sci· January 2023

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RNA sequencing and weighted gene co-expression network analysis uncover the hub genes controlling cold tolerance in seedlings.
Mingjun Cheng, Zeyang Pan, Kuoshu Cui, Junjun Zheng, Xuan Luo, Youjun Chen

Front Plant Sci· September 2022

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The microbiota diversity of seeds in Qinghai-Tibet Plateau and their relationship with environments.
Yue Gao, Youjun Chen, Yang Luo, Junying Liu, Pei Tian

Front Microbiol· August 2022

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Responses of photosynthetic characteristics of oat flag leaf and spike to drought stress.
Haoqi Tian, Qingping Zhou, Wenhui Liu, Jing Zhang, Youjun Chen

Front Plant Sci· July 2022

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