Publications by authors named "Young-Man Cho"

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EpCAM and APN expression in combination with γ-H2AX as biomarkers for detecting hepatocarcinogens in rats.
Jun-Ichi Akagi, Young-Man Cho, Takeshi Toyoda, Yasuko Mizuta, Kumiko Ogawa

Cancer Sci· December 2023

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A formamidopyrimidine derivative from the deoxyguanosine adduct produced by food contaminant acrylamide induces DNA replication block and mutagenesis.
Jun-Ichi Akagi, Masayuki Yokoi, Yumi Miyake, Tsuyoshi Shirai, Tomohiro Baba, Young-Man Cho

J Biol Chem· August 2023

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Early detection of hepatocarcinogens in rats by immunohistochemistry of γ-H2AX.
Takeshi Toyoda, Mizuki Sone, Kohei Matsushita, Hirotoshi Akane, Jun-Ichi Akagi, Young-Man Cho

J Toxicol Sci· June 2023

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Histopathological and immunohistochemical evaluation for detecting changes in blood hormone levels caused by endocrine disruptors in a 28-day repeated-dose study in rats.
Hirotoshi Akane, Takeshi Toyoda, Yasuko Mizuta, Young-Man Cho, Tetsuya Ide

J Appl Toxicol· October 2022

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Persistent γ-H2AX Formation and Expression of Stem Cell Markers in N-Butyl-N-(4-Hydroxybutyl)Nitrosamine-Induced Bladder Carcinogenesis in Rats.
Takanori Yamada, Takeshi Toyoda, Kohei Matsushita, Hirotoshi Akane, Tomomi Morikawa, Young-Man Cho

Toxicol Sci· August 2022

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Spontaneous adenolipoma of the mammary gland in the male F344 rat.
Tetsuya Ide, Young-Man Cho, Yuji Oishi, Kumiko Ogawa

J Toxicol Pathol· July 2021

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Expression of stem cell markers as useful complementary factors in the early detection of urinary bladder carcinogens by immunohistochemistry for γ-H2AX.
Takanori Yamada, Takeshi Toyoda, Kohei Matsushita, Young-Man Cho, Jun-Ichi Akagi

Arch Toxicol· February 2021

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A 90-day repeated oral dose toxicity study of four stereoisomers of 2,4-dimethyl-4-phenyltetrahydrofuran, a synthetic flavoring substance, in F344 rats.
Tetsuya Ide, Yasuko Mizuta, Jun-Ichi Akagi, Naoko Masumoto, Naoki Sugimoto, Young-Man Cho

Regul Toxicol Pharmacol· July 2020

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A 13-week subchronic toxicity study of hexyl acetate in SD rats.
Takeshi Toyoda, Young-Man Cho, Kohei Matsushita, Shigehiro Tachibana, Mika Senuma

J Toxicol Pathol· July 2019

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Immunohistochemistry of γ-H2AX as a method of early detection of urinary bladder carcinogenicity in mice.
Mizuki Sone, Takeshi Toyoda, Young-Man Cho, Jun-Ichi Akagi, Kohei Matsushita

J Appl Toxicol· June 2019

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Dimethylarsinic acid may promote prostate carcinogenesis in rats.
Shugo Suzuki, Takeshi Toyoda, Hiroyuki Kato, Aya Naiki-Ito, Yoriko Yamashita, Young-Man Cho

J Toxicol Pathol· April 2019

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Subchronic toxicity evaluation of isoeugenyl methyl ether in F344/DuCrj rats by 13-week oral administration.
Jun-Ichi Akagi, Young-Man Cho, Yasuko Mizuta, Chiye Tatebe, Kyoko Sato

Regul Toxicol Pharmacol· March 2019

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4-Methylthio-3-butenyl isothiocyanate (MTBITC) induced apoptotic cell death and G2/M cell cycle arrest via ROS production in human esophageal epithelial cancer cells.
Tadashi Hirata, Young-Man Cho, Isamu Suzuki, Takeshi Toyoda, Jun-Ichi Akagi

J Toxicol Sci· February 2019

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Twist1 was detected in mesenchymal cells of mammary fibroadenoma and invasive components of breast carcinoma in rats.
Satomi Funahashi, Yasumasa Okazaki, Hirotaka Nagai, Shan Hwu Chew, Kumiko Ogawa, Young-Man Cho

J Toxicol Pathol· January 2019

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Subchronic toxicity evaluation of 5-hexenyl isothiocyanate, a nature identical flavoring substance from Wasabia japonica, in F344/DuCrj rats.
Jun-Ichi Akagi, Young-Man Cho, Yasuko Mizuta, Takeshi Toyoda, Kumiko Ogawa

Food Chem Toxicol· December 2018

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A 13-week subchronic toxicity study of acetaminophen using an obese rat model.
Takeshi Toyoda, Young-Man Cho, Jun-Ichi Akagi, Yasuko Mizuta, Kohei Matsushita

J Toxicol Sci· August 2018

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4-Methylthio-3-butenyl isothiocyanate mediates nuclear factor (erythroid-derived 2)-like 2 activation by regulating reactive oxygen species production in human esophageal epithelial cells.
Tadashi Hirata, Young-Man Cho, Isamu Suzuki, Takeshi Toyoda, Jun-Ichi Akagi

Food Chem Toxicol· January 2018

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Hypersensitivity of mouse embryonic fibroblast cells defective for DNA polymerases η, ι and κ to various genotoxic compounds: Its potential for application in chemical genotoxic screening.
Junichi Akagi, Masayuki Yokoi, Young-Man Cho, Takeshi Toyoda, Haruo Ohmori

DNA Repair (Amst)· January 2018

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Size-dependent acute toxicity of silver nanoparticles in mice.
Young-Man Cho, Yasuko Mizuta, Jun-Ichi Akagi, Takeshi Toyoda, Mizuki Sone

J Toxicol Pathol· January 2018

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Horseradish extract promotes urinary bladder carcinogenesis when administered to F344 rats in drinking water.
Young-Man Cho, Mai Hasumura, Toshio Imai, Shigeaki Takami, Akiyoshi Nishikawa

J Appl Toxicol· July 2017

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Lack of in vivo mutagenicity of 1,2-dichloropropane and dichloromethane in the livers of gpt delta rats administered singly or in combination.
Tadashi Hirata, Young-Man Cho, Takeshi Toyoda, Jun-Ichi Akagi, Isamu Suzuki

J Appl Toxicol· June 2017

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Altered susceptibility of an obese rat model to 13-week subchronic toxicity induced by 3-monochloropropane-1,2-diol.
Takeshi Toyoda, Young-Man Cho, Jun-Ichi Akagi, Yasuko Mizuta, Kohei Matsushita

J Toxicol Sci· May 2017

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Toxic effects of 4-methylthio-3-butenyl isothiocyanate (Raphasatin) in the rat urinary bladder without genotoxicity.
Isamu Suzuki, Young-Man Cho, Tadashi Hirata, Takeshi Toyoda, Jun-Ichi Akagi

J Appl Toxicol· April 2017

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4-Methylthio-3-butenyl isothiocyanate (raphasatin) exerts chemopreventive effects against esophageal carcinogenesis in rats.
Isamu Suzuki, Young-Man Cho, Tadashi Hirata, Takeshi Toyoda, Jun-Ichi Akagi

J Toxicol Pathol· October 2016

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Orally administered glycidol and its fatty acid esters as well as 3-MCPD fatty acid esters are metabolized to 3-MCPD in the F344 rat.
Saeko Onami, Young-Man Cho, Takeshi Toyoda, Jun-ichi Akagi, Satoshi Fujiwara

Regul Toxicol Pharmacol· December 2015

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