Publications by authors named "Yu Hara"

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Clinical Impact of Mepolizumab on Airway Mucus Plugs in Patients with Severe Asthma.
Yu Hara, Naoya Tanabe, Satoshi Marumo, Kota Murohashi, Yusuke Hayashi

J Asthma Allergy· December 2025

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Familial fibrotic hypersensitivity pneumonitis: A distinct clinical phenotype with shorter leukocyte telomere length.
Masashi Nishimura, Hideya Kitamura, Yoichi Tagami, Kazushi Fujimoto, Takashi Fukushima, Yu Hara

Respir Investig· November 2025

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Lipolysis-microlipophagy cascade regulated by adipose triglyceride lipase drives pathogenic adaptive type 2 immunity.
Hiroyuki Yagyu, Masahiro Kiuchi, Atsushi Sasaki, Eisuke Itakura, Kota Kokubo, Yu Hara, Kiyoshi Hirahara

Sci Immunol· October 2025

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Valid surrogate end-points in nonsmall cell lung cancer peri-operative systemic therapy trials: a systematic review.
Kohei Somekawa, Nobuyuki Horita, Satoshi Nagaoka, Yukihito Kajita, Suguru Muraoka, Yu Hara

Eur Respir Rev· October 2025

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iPSC-based drug discovery identified the Hippo signaling pathway as a therapeutic target in the fibrosis of NPHP1-deficient nephronophthisis.
Takefumi Suzuki, Koichiro Susa, Hiroaki Kikuchi, Yuta Nakano, Tomoki Yanagi, Yu Hara, Eisei Sohara

Stem Cell Res Ther· September 2025

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Exploring factors associated with clinical remission in patients with severe asthma receiving anti-IL-4Rα, anti-IL-5/5R, or anti-IgE treatment.
Shota Takahashi, Naoya Tanabe, Satoshi Marumo, Yu Hara, Yusuke Hayashi

Respir Investig· July 2025

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MiR-200a regulates PD-L1 and predicts response to immune checkpoint inhibitors in advanced non-small cell lung cancer.
Ayami Kaneko, Nobuaki Kobayashi, Sousuke Kubo, Satoshi Nagaoka, Suguru Muraoka, Yu Hara

Transl Lung Cancer Res· July 2025

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Real-world efficacy of immune checkpoint inhibitors in PD-L1 negative non-small cell lung cancer: a multicenter retrospective study.
Suguru Muraoka, Nobuaki Kobayashi, Ayami Kaneko, Kohei Somekawa, Yukihito Kajita, Toshinori Tsukahara, Yu Hara

Transl Lung Cancer Res· July 2025

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Rapid detection of non-small cell lung cancer driver mutations using droplet digital polymerase chain reaction analysis of bronchial washings: a prospective multicenter study.
Kohei Somekawa, Nobuaki Kobayashi, Satoshi Nagaoka, Kenichi Seki, Yukihito Kajita, Yu Hara

Transl Lung Cancer Res· February 2025

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Causative diseases of bloody sputum and hemoptysis in respiratory clinics in Japan.
Ryo Atsuta, Hiroaki Fujii, Yu Hara, Hiroshi Tanaka, Kei Nakamura, Shusaku Haranaga

Respir Investig· January 2025

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Benefit-Risk Profile of P2X3 Receptor Antagonists for Treatment of Chronic Cough: Dose-Response Model-Based Network Meta-Analysis.
Shota Yamamoto, Nobuyuki Horita, Johsuke Hara, Mao Sasamoto, Yoshihiro Kanemitsu, Yu Hara

Chest· November 2024

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ULK1-regulated AMP sensing by AMPK and its application for the treatment of chronic kidney disease.
Tomoki Yanagi, Hiroaki Kikuchi, Koh Takeuchi, Koichiro Susa, Takayasu Mori, Yu Hara, Eisei Sohara

Kidney Int· November 2024

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A protocol for a Japanese prospective cohort evaluating the features of patients with uncontrolled asthma achieving clinical remission: J-CIRCLE.
Naoya Tanabe, Yu Hara, Kaoruko Shimizu, Satoshi Marumo, Jun Miyata

Respir Investig· November 2024

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[Clinical Management of Respiratory Diseases in Neurosurgical Settings].
Hiroyuki Yagyu, Yu Hara, Takeshi Kaneko

No Shinkei Geka· November 2024

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Importance of in Patients with Polycystic Kidney Disease Without a Family History.
Takuya Fujimaru, Takayasu Mori, Akinari Sekine, Motoko Chiga, Shintaro Mandai, Yu Hara, Eisei Sohara

Kidney Int Rep· September 2024

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High red blood cell distribution width attenuates the effectiveness of Immune checkpoint inhibitor therapy: An exploratory study using a clinical data warehouse.
Hiromi Matsumoto, Taichi Fukushima, Nobuaki Kobayashi, Yuuki Higashino, Suguru Muraoka, Yu Hara

PLoS One· August 2024

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Geographic and economic influences on benralizumab prescribing for severe asthma in Japan.
Nobuaki Kobayashi, Hiromi Matsumoto, Kohei Somekawa, Ayami Kaneko, Nobuhiko Fukuda, Yu Hara

Sci Rep· July 2024

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HLA-DQA1*01:03 and DQB1*06:01 are risk factors for severe COVID-19 pneumonia.
Katsushi Tanaka, Akira Meguro, Yu Hara, Lisa Endo, Ami Izawa

HLA· July 2024

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Efficacy and safety of benralizumab in elderly patients with severe eosinophilic asthma.
Kohei Somekawa, Keisuke Watanabe, Kenichi Seki, Suguru Muraoka, Ami Izawa, Yu Hara

Eur Clin Respir J· July 2024

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Nationwide survey in Japan of the causative diseases of bloody sputum and hemoptysis in departments of respiratory medicine at university hospitals and core hospitals.
Hiroaki Fujii, Yu Hara, Yasushi Obase, Shusaku Haranaga, Hidenori Takahashi

Respir Investig· May 2024

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Real-world evidence of efficacy of pembrolizumab plus chemotherapy and nivolumab plus ipilimumab plus chemotherapy as initial treatment for advanced non-small cell lung cancer.
Ayami Kaneko, Nobuaki Kobayashi, Kenji Miura, Hiromi Matsumoto, Kohei Somekawa, Toshinori Tsukahara, Yu Hara

Thorac Cancer· May 2024

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Efficacy and safety of macrolide therapy for adult asthma: A systematic review and meta-analysis.
Yosuke Fukuda, Nobuyuki Horita, Masaharu Aga, Fumihiro Kashizaki, Yu Hara

Respir Investig· March 2024

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Improved diagnostic accuracy with three lung tumor markers compared to six-marker panel.
Ami Izawa, Yu Hara, Nobuyuki Horita, Suguru Muraoka, Megumi Kaneko

Transl Lung Cancer Res· March 2024

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ILD-GAP combined with the monocyte ratio could be a better prognostic prediction model than ILD-GAP in patients with interstitial lung diseases.
Momo Hirata, Yu Hara, Hiroaki Fujii, Kota Murohashi, Yusuke Saigusa

BMC Pulm Med· January 2024

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Serum heme oxygenase-1 as a prognostic biomarker in patients with acute exacerbation of interstitial lung disease.
Yoichi Tagami, Yu Hara, Kota Murohashi, Ryo Nagasawa, Hiroaki Fujii

Sci Rep· December 2023

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