Publications by authors named "Yu Sakurai"

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The stress-responsive cytotoxic effect of diesel exhaust particles on lymphatic endothelial cells.
Yu Sakurai, Eiki Oba, Akiko Honda, Hiroki Tanaka, Hirohisa Takano

Sci Rep· May 2024

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Lymphatic Endothelial Cells Produce Chemokines in Response to the Lipid Nanoparticles Used in RNA Vaccines.
Yi Liu, Miho Suzuoki, Hiroki Tanaka, Yu Sakurai, Hiroto Hatakeyama

Biol Pharm Bull· March 2024

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The Effect of Cholesterol Content on the Adjuvant Activity of Nucleic-Acid-Free Lipid Nanoparticles.
Jessica Anindita, Hiroki Tanaka, Takuma Yamakawa, Yuka Sato, Chika Matsumoto, Yu Sakurai

Pharmaceutics· January 2024

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[A Case of Pathological Complete Response Following Neoadjuvant S-1 Monotherapy in an Elderly Patient with Locally Advanced Breast Cancer].
Takayuki Terasawa, Yu Sakurai, Ai Yanai, Kaori Fukuda, Rie Shibuya

Gan To Kagaku Ryoho· December 2023

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Development of a Ready-to-Use-Type RNA Vaccine Carrier Based on an Intracellular Environment-Responsive Lipid-like Material with Immune-Activating Vitamin E Scaffolds.
Jessica Anindita, Hiroki Tanaka, Ryotaro Oyama, Shinya Hagiwara, Daiki Shirane, Yu Sakurai

Pharmaceutics· November 2023

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An Ionizable Lipid Material with a Vitamin E Scaffold as an mRNA Vaccine Platform for Efficient Cytotoxic T Cell Responses.
Ryotaro Oyama, Harumichi Ishigame, Hiroki Tanaka, Naho Tateshita, Moeko Itazawa, Yu Sakurai

ACS Nano· October 2023

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Logistics and distribution of small extracellular vesicles from the subcutaneous space to the lymphatic system.
Yu Sakurai, Asa Ohtani, Yuka Nakayama, Masaki Gomi, Takeshi Masuda

J Control Release· September 2023

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Tolerogenic Lipid Nanoparticles for Delivering Self-Antigen mRNA for the Treatment of Experimental Autoimmune Encephalomyelitis.
Masaki Gomi, Yuka Nakayama, Yu Sakurai, Ryotaro Oyama, Koki Iwasaki

Pharmaceuticals (Basel)· September 2023

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Development of an Alcohol Dilution-Lyophilization Method for the Preparation of mRNA-LNPs with Improved Storage Stability.
Daiki Shirane, Hiroki Tanaka, Yu Sakurai, Sakura Taneichi, Yuta Nakai

Pharmaceutics· June 2023

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Delivering mRNA to Secondary Lymphoid Tissues by Phosphatidylserine-Loaded Lipid Nanoparticles.
Masaki Gomi, Yu Sakurai, Minami Sato, Hiroki Tanaka, Yumi Miyatake

Adv Healthc Mater· April 2023

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Reactivation of Anticancer Immunity by Resetting Interorgan Crosstalk in Immune-Suppressive Cells with a Nanoparticulated Anti-Inflammatory Drug.
Mizuki Doi, Hiroki Tanaka, Takara Ohoto, Naoya Miura, Yu Sakurai

Small· April 2023

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Ready-to-Use-Type Lyophilized Lipid Nanoparticle Formulation for the Postencapsulation of Messenger RNA.
Hiroki Tanaka, Shinya Hagiwara, Daiki Shirane, Takuma Yamakawa, Yuka Sato, Yu Sakurai

ACS Nano· February 2023

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siRNA delivery to lymphatic endothelial cells via ApoE-mediated uptake by lipid nanoparticles.
Yu Sakurai, Keito Yoshikawa, Kenta Arai, Akira Kazaoka, Shigeki Aoki

J Control Release· January 2023

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Delivery of aPD-L1 antibody to i.p. tumors via direct penetration by i.p. route: Beyond EPR effect.
Mayu Yamamoto, Taiki Kurino, Reiko Matsuda, Haleigh Sakura Jones, Yoshito Nakamura, Yu Sakurai

J Control Release· December 2022

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Targeted delivery of lipid nanoparticle to lymphatic endothelial cells via anti-podoplanin antibody.
Yu Sakurai, Nodoka Abe, Keito Yoshikawa, Ryotaro Oyama, Satoshi Ogasawara

J Control Release· September 2022

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Development of siRNA Delivery System by Lipid Nanoparticles Modified with Functional Materials for Cancer Treatment.
Yu Sakurai

Biol Pharm Bull· August 2022

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pH-Responsive Lipid Nanoparticles Achieve Efficient mRNA Transfection in Brain Capillary Endothelial Cells.
Yu Sakurai, Himeka Watanabe, Kazuma Nishio, Kohei Hashimoto, Atsuki Harada

Pharmaceutics· July 2022

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Novel antiangiogenic therapy targeting biglycan using tumor endothelial cell-specific liposomal siRNA delivery system.
Nako Maishi, Yu Sakurai, Hiroto Hatakeyama, Yui Umeyama, Takashi Nakamura

Cancer Sci· May 2022

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Proteomics Analysis of Lymphatic Metastasis-Related Proteins Using Highly Metastatic Human Melanoma Cells Originated by Sequential in Vivo Implantation.
Katsuyuki Chida, Yu Sakurai, Asa Ohtani, Takeshi Masuda, Sumio Ohtsuki

Biol Pharm Bull· January 2022

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Improvement of mRNA Delivery Efficiency to a T Cell Line by Modulating PEG-Lipid Content and Phospholipid Components of Lipid Nanoparticles.
Hiroki Tanaka, Ryo Miyama, Yu Sakurai, Shinya Tamagawa, Yuta Nakai

Pharmaceutics· December 2021

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Development of lipid-like materials for RNA delivery based on intracellular environment-responsive membrane destabilization and spontaneous collapse.
Hiroki Tanaka, Yu Sakurai, Jessica Anindita, Hidetaka Akita

Adv Drug Deliv Rev· September 2021

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Optimization of Sentinel Lymph Node Imaging Methodology Using Anionic Liposome and Hyaluronidase.
Yu Sakurai, Miho Suzuoki, Masaki Gomi, Hiroki Tanaka, Hidetaka Akita

Pharmaceutics· September 2021

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Delivery of Oligonucleotides Using a Self-Degradable Lipid-Like Material.
Hiroki Tanaka, Nae Takata, Yu Sakurai, Tokuyuki Yoshida, Takao Inoue

Pharmaceutics· April 2021

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Development of Sentinel LN Imaging with a Combination of HAase Based on a Comprehensive Analysis of the Intra-lymphatic Kinetics of LPs.
Masaki Gomi, Yu Sakurai, Takaharu Okada, Naoya Miura, Hiroki Tanaka

Mol Ther· January 2021

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Silencing of VEGFR2 by RGD-Modified Lipid Nanoparticles Enhanced the Efficacy of Anti-PD-1 Antibody by Accelerating Vascular Normalization and Infiltration of T Cells in Tumors.
Riki Cho, Yu Sakurai, Haleigh Sakura Jones, Hidetaka Akita, Akihiro Hisaka

Cancers (Basel)· December 2020

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