Publications by authors named "Yuan-Ta Lin"

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Opposing roles of p38α-mediated phosphorylation and PRMT1-mediated arginine methylation in driving TDP-43 proteinopathy.
Mari Aikio, Hana M Odeh, Heike J Wobst, Bo Lim Lee, Úna Chan, Yuan-Ta Lin

Cell Rep· March 2025

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Opposing roles of p38α-mediated phosphorylation and PRMT1-mediated arginine methylation in driving TDP-43 proteinopathy.
Mari Aikio, Hana M Odeh, Heike J Wobst, Bo Lim Lee, Úna Chan, Yuan-Ta Lin

Cell Rep· January 2025

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Author Correction: APOE4 impairs myelination via cholesterol dysregulation in oligodendrocytes.
Joel W Blanchard, Leyla Anne Akay, Jose Davila-Velderrain, Djuna von Maydell, Hansruedi Mathys, Yuan-Ta Lin

Nature· December 2024

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APOE4 impairs myelination via cholesterol dysregulation in oligodendrocytes.
Joel W Blanchard, Leyla Anne Akay, Jose Davila-Velderrain, Djuna von Maydell, Hansruedi Mathys, Yuan-Ta Lin

Nature· November 2022

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Telomerase Reverse Transcriptase Preserves Neuron Survival and Cognition in Alzheimer's Disease Models.
Hong Seok Shim, James W Horner, Chang-Jiun Wu, Jiexi Li, Zheng D Lan, Yuan-Ta Lin

Nat Aging· December 2021

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APOE4-carrying human astrocytes oversupply cholesterol to promote neuronal lipid raft expansion and Aβ generation.
Se-In Lee, Woojin Jeong, Heejin Lim, Sukhee Cho, Hyein Lee, Yuan-Ta Lin

Stem Cell Reports· September 2021

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Author Correction: Reconstruction of the human blood-brain barrier in vitro reveals a pathogenic mechanism of APOE4 in pericytes.
Joel W Blanchard, Michael Bula, Jose Davila-Velderrain, Leyla Anne Akay, Lena Zhu, Yuan-Ta Lin

Nat Med· February 2021

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PICALM Rescues Endocytic Defects Caused by the Alzheimer's Disease Risk Factor APOE4.
Priyanka Narayan, Grzegorz Sienski, Julia M Bonner, Yuan-Ta Lin, Jinsoo Seo, Susan Lindquist

Cell Rep· October 2020

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Reconstruction of the human blood-brain barrier in vitro reveals a pathogenic mechanism of APOE4 in pericytes.
Joel W Blanchard, Michael Bula, Jose Davila-Velderrain, Leyla Anne Akay, Lena Zhu, Yuan-Ta Lin

Nat Med· June 2020

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REST and Neural Gene Network Dysregulation in iPSC Models of Alzheimer's Disease.
Katharina Meyer, Heather M Feldman, Tao Lu, Derek Drake, Elaine T Lim, King-Hwa Ling, Yuan-Ta Lin

Cell Rep· January 2019

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APOE4 Causes Widespread Molecular and Cellular Alterations Associated with Alzheimer's Disease Phenotypes in Human iPSC-Derived Brain Cell Types.
Yuan-Ta Lin, Jinsoo Seo, Fan Gao, Heather M Feldman, Hsin-Lan Wen

Neuron· June 2018

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APOE4 Causes Widespread Molecular and Cellular Alterations Associated with Alzheimer's Disease Phenotypes in Human iPSC-Derived Brain Cell Types.
Yuan-Ta Lin, Jinsoo Seo, Fan Gao, Heather M Feldman, Hsin-Lan Wen

Neuron· June 2018

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Inhibition of p25/Cdk5 Attenuates Tauopathy in Mouse and iPSC Models of Frontotemporal Dementia.
Jinsoo Seo, Oleg Kritskiy, L Ashley Watson, Scarlett J Barker, Dilip Dey, Yuan-Ta Lin

J Neurosci· October 2017

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Self-Organizing 3D Human Neural Tissue Derived from Induced Pluripotent Stem Cells Recapitulate Alzheimer's Disease Phenotypes.
Waseem K Raja, Alison E Mungenast, Yuan-Ta Lin, Tak Ko, Fatema Abdurrob

PLoS One· August 2017

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Histone deacetylase 3 associates with MeCP2 to regulate FOXO and social behavior.
Alexi Nott, Jemmie Cheng, Fan Gao, Yuan-Ta Lin, Elizabeta Gjoneska

Nat Neurosci· November 2016

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Disruption of the nuclear membrane by perinuclear inclusions of mutant huntingtin causes cell-cycle re-entry and striatal cell death in mouse and cell models of Huntington's disease.
Kuan-Yu Liu, Yu-Chiau Shyu, Brett A Barbaro, Yuan-Ta Lin, Yijuang Chern

Hum Mol Genet· March 2015

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Human mesenchymal stem cells prolong survival and ameliorate motor deficit through trophic support in Huntington's disease mouse models.
Yuan-Ta Lin, Yijuang Chern, Che-Kun James Shen, Hsin-Lan Wen, Ya-Chin Chang

PLoS One· February 2012

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Stathmin, a microtubule-destabilizing protein, is dysregulated in spinal muscular atrophy.
Hsin-Lan Wen, Yuan-Ta Lin, Chen-Hung Ting, Sue Lin-Chao, Hung Li

Hum Mol Genet· May 2010

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Defining a link with autosomal-dominant polycystic kidney disease in mice with congenitally low expression of Pkd1.
Si-Tse Jiang, Yuan-Yow Chiou, Ellian Wang, Hsiu-Kuan Lin, Yuan-Ta Lin

Am J Pathol· January 2006

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