Publications by authors named "Yuki Shiimura"

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Discovery of Feeding Regulatory Peptides and The Importance of Peptide Discovery Research.
Takanori Ida, Kazuma Matsui, Sayaka Nagata, Tomoya Nakamachi, Yuki Shiimura

Kurume Med J· November 2025

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Ghrelin-LEAP2 interactions along the stomach-liver axis.
Katsuya Sakai, Yuki Nakazato, Yuki Shiimura, Weidong Zhang, Masamitsu Nakazato

Endocr J· April 2025

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A cryptic pocket in CB1 drives peripheral and functional selectivity.
Vipin Ashok Rangari, Evan S O'Brien, Alexander S Powers, Richard A Slivicki, Zachariah Bertels, Yuki Shiimura

Nature· April 2025

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How the ghrelin receptor recognizes the acyl-modified orexigenic hormone.
Yuki Shiimura, Masayasu Kojima, Takahiro Sato

Front Mol Neurosci· April 2025

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The structure and function of the ghrelin receptor coding for drug actions.
Yuki Shiimura, Dohyun Im, Ryosuke Tany, Hidetsugu Asada, Ryoji Kise

Nat Struct Mol Biol· March 2025

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Virtual library docking for cannabinoid-1 receptor agonists with reduced side effects.
Tia A Tummino, Christos Iliopoulos-Tsoutsouvas, Joao M Braz, Evan S O'Brien, Reed M Stein, Yuki Shiimura

Nat Commun· March 2025

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[Ghrelin and its receptor: a gut-brain hormone system as a therapeutic target for cancer cachexia].
Yuki Shiimura, Taito Inoue, Takahiro Sato

Nihon Yakurigaku Zasshi· January 2025

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Neurotransmitter recognition by human vesicular monoamine transporter 2.
Dohyun Im, Mika Jormakka, Narinobu Juge, Jun-Ichi Kishikawa, Takayuki Kato, Yuki Shiimura

Nat Commun· September 2024

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A µ-opioid receptor modulator that works cooperatively with naloxone.
Evan S O'Brien, Vipin Ashok Rangari, Amal El Daibani, Shainnel O Eans, Haylee R Hammond, Yuki Shiimura

Nature· July 2024

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Acyl modifications in bovine, porcine, and equine ghrelins.
Takanori Ida, Hatsumi Tominaga, Eri Iwamoto, Akito Kurogi, Ayaka Okura, Yuki Shiimura

Front Endocrinol (Lausanne)· June 2024

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Large library docking for cannabinoid-1 receptor agonists with reduced side effects.
Tia A Tummino, Christos Iliopoulos-Tsoutsouvas, Joao M Braz, Evan S O'Brien, Reed M Stein, Yuki Shiimura

bioRxiv· February 2024

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Structural insights into the agonists binding and receptor selectivity of human histamine H receptor.
Dohyun Im, Jun-Ichi Kishikawa, Yuki Shiimura, Hiromi Hisano, Akane Ito

Nat Commun· October 2023

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Insights Into the Regulation of Offspring Growth by Maternally Derived Ghrelin.
Takahiro Sato, Takanori Ida, Yuki Shiimura, Kazuma Matsui, Kanae Oishi

Front Endocrinol (Lausanne)· April 2022

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Endogenous agonist-bound S1PR3 structure reveals determinants of G protein-subtype bias.
Shintaro Maeda, Yuki Shiimura, Hidetsugu Asada, Kunio Hirata, Fangjia Luo

Sci Adv· June 2021

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Structure of the dopamine D receptor in complex with the antipsychotic drug spiperone.
Dohyun Im, Asuka Inoue, Takaaki Fujiwara, Takanori Nakane, Yasuaki Yamanaka, Yuki Shiimura

Nat Commun· December 2020

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Structure of an antagonist-bound ghrelin receptor reveals possible ghrelin recognition mode.
Yuki Shiimura, Shoichiro Horita, Akie Hamamoto, Hidetsugu Asada, Kunio Hirata

Nat Commun· August 2020

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Expression of the ghrelin/growth hormone secretagogue receptor axis and its functional role in promoting tumor growth in primary central nervous system lymphomas.
Hiroko Muta, Yasuo Sugita, Takuya Furuta, Yuki Shiimura, Koichi Ohshima

Neuropathology· June 2020

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The Crystal Structure of Angiotensin II Type 2 Receptor with Endogenous Peptide Hormone.
Hidetsugu Asada, Asuka Inoue, Francois Marie Ngako Kadji, Kunio Hirata, Yuki Shiimura

Structure· April 2020

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Ligand binding to human prostaglandin E receptor EP at the lipid-bilayer interface.
Yosuke Toyoda, Kazushi Morimoto, Ryoji Suno, Shoichiro Horita, Keitaro Yamashita, Yuki Shiimura

Nat Chem Biol· January 2019

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Crystal structure of the human angiotensin II type 2 receptor bound to an angiotensin II analog.
Hidetsugu Asada, Shoichiro Horita, Kunio Hirata, Mitsunori Shiroishi, Yuki Shiimura

Nat Struct Mol Biol· July 2018

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Physiological roles of ghrelin on obesity.
Takahiro Sato, Takanori Ida, Yuki Nakamura, Yuki Shiimura, Kenji Kangawa

Obes Res Clin Pract· May 2015

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Regulation of the Human Ghrelin Promoter Activity by Transcription Factors, NF-κB and Nkx2.2.
Yuki Shiimura, Hideko Ohgusu, Takahiro Sato, Masayasu Kojima

Int J Endocrinol· February 2015

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FABP3 and brown adipocyte-characteristic mitochondrial fatty acid oxidation enzymes are induced in beige cells in a different pathway from UCP1.
Yuki Nakamura, Takahiro Sato, Yuki Shiimura, Yoshiki Miura, Masayasu Kojima

Biochem Biophys Res Commun· November 2013

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Structure, regulation and function of ghrelin.
Takahiro Sato, Yuki Nakamura, Yuki Shiimura, Hideko Ohgusu, Kenji Kangawa

J Biochem· February 2012

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I-mfa domain proteins specifically interact with SERTA domain proteins and repress their transactivating functions.
Shuichi Kusano, Yuki Shiimura, Yoshito Eizuru

Biochimie· September 2011

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