Publications by authors named "Yukia Shimura"

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Human Plasma and Urine Concentrations of Triethylamine and Its N-Oxide after Oral Administration Extrapolated Using Pharmacokinetic Modeling: Comparison with Trimethylamine and Its N-Oxide.
Makiko Shimizu, Yukia Shimura, Hiroshi Yamazaki

Biol Pharm Bull· November 2025

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Virtual Hepatic and Plasma Exposures of Voriconazole Administered to Cytochrome P450 2C19 Poor Metabolizers Predicted by Simplified and Full Pharmacokinetic Modeling Systems: Possible Causal Factor for Hepatic Disorders Seen in a Japanese Database.
Koichiro Adachi, Katsuhiro Ohyama, Yukia Shimura, Yoichi Tanaka, Makiko Shimizu

Biol Pharm Bull· August 2025

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Reported liver toxicity of food chemicals in rats extrapolated to humans using virtual human-to-rat hepatic concentration ratios generated by pharmacokinetic modeling with machine learning-derived parameters.
Koichiro Adachi, Manato Hosoi, Yukia Shimura, Makiko Shimizu, Hiroshi Yamazaki

J Toxicol Sci· May 2025

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