Publications by authors named "Yukiya Hashimoto"

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Functional characteristics of a renal H/lipophilic cation antiport system in porcine LLC-PK cells and rats.
Ryutaro Matsui, Ryutaro Hattori, Youhei Usami, Masumi Koyama, Yuki Hirayama, Yukiya Hashimoto

Drug Metab Pharmacokinet· February 2018

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The true distribution volume and bioavailability of mizoribine in children with chronic kidney disease.
Takuhito Nagai, Osamu Uemura, Hisashi Kaneda, Katsumi Ushijima, Kazuhide Ohta, Yukiya Hashimoto

Clin Exp Nephrol· October 2017

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Presence of an H/Quinidine Antiport System in Madin-Darby Canine Kidney Cells.
Miki Fukao, Eri Kondo, Hiroki Nishino, Ryutaro Hattori, Asuka Horie, Yukiya Hashimoto

Eur J Drug Metab Pharmacokinet· December 2016

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Population pharmacokinetics of mizoribine in pediatric patients with kidney disease.
Hisashi Kaneda, Masaki Shimizu, Kazuhide Ohta, Katsumi Ushijima, Yoshimitsu Gotoh, Yukiya Hashimoto

Clin Exp Nephrol· October 2016

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Variability of bioavailability and intestinal absorption mechanisms of metoprolol.
Miki Fukao, Kazuya Ishida, Asuka Horie, Masato Taguchi, Takashi Nozawa, Yukiya Hashimoto

Drug Metab Pharmacokinet· December 2014

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Membrane transport mechanisms of choline in human intestinal epithelial LS180 cells.
Asuka Horie, Kazuya Ishida, Yuri Watanabe, Kaito Shibata, Yukiya Hashimoto

Biopharm Drug Dispos· December 2014

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Variability of bioavailability and intestinal absorption characteristics of bisoprolol.
Kazuya Ishida, Asuka Horie, Maki Nishimura, Masato Taguchi, Nozomu Fujii, Yukiya Hashimoto

Drug Metab Pharmacokinet· September 2014

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Pharmacokinetic variability of flecainide in younger Japanese patients and mechanisms for renal excretion and intestinal absorption.
Asuka Horie, Kazuya Ishida, Kaito Shibata, Masato Taguchi, Ayaka Ozawa, Yukiya Hashimoto

Biopharm Drug Dispos· April 2014

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Effect of chronic hypoxic hypoxia on oxidation and glucuronidation of carvedilol in rats.
Shizuka Yamaura, Miki Fukao, Kazuya Ishida, Masato Taguchi, Yukiya Hashimoto

Eur J Drug Metab Pharmacokinet· March 2014

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Effect of salt intake on bioavailability of mizoribine in healthy Japanese males.
Kazuya Ishida, Miki Fukao, Hitomi Watanabe, Masato Taguchi, Toshio Miyawaki, Yukiya Hashimoto

Drug Metab Pharmacokinet· August 2013

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Population pharmacokinetics of mizoribine in pediatric recipients of renal transplantation.
Kazuya Ishida, Osamu Motoyama, Seiichiro Shishido, Kazuo Tsuzuki, Yukiya Hashimoto

Clin Exp Nephrol· October 2012

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Effect of genetic polymorphisms of SLC28A1, ABCG2, and ABCC4 on bioavailability of mizoribine in healthy Japanese males.
Miki Fukao, Kazuya Ishida, Takuya Sakamoto, Masato Taguchi, Hiroyoshi Matsukura, Yukiya Hashimoto

Drug Metab Pharmacokinet· March 2012

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Population pharmacokinetics of mizoribine in adult recipients of renal transplantation.
Kazuya Ishida, Masahiko Okamoto, Michio Ishibashi, Yukiya Hashimoto

Clin Exp Nephrol· December 2011

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Mechanisms for membrane transport of metformin in human intestinal epithelial Caco-2 cells.
Asuka Horie, Jumpei Sakata, Maki Nishimura, Kazuya Ishida, Masato Taguchi, Yukiya Hashimoto

Biopharm Drug Dispos· July 2011

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Evaluation of limited sampling designs to estimate maximal concentration and area under the curve of mizoribine in pediatric patients with renal disease.
Kazuya Ishida, Hisashi Kaneda, Osamu Uemura, Katsumi Ushijima, Kazuhide Ohta, Yukiya Hashimoto

Drug Metab Pharmacokinet· June 2011

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Effect of the VKORC1 genotype on warfarin dose requirements in Japanese pediatric patients.
Yuya Kato, Fukiko Ichida, Kazuyoshi Saito, Kazuhiro Watanabe, Keiichi Hirono, Yukiya Hashimoto

Drug Metab Pharmacokinet· June 2011

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Pharmacokinetics of bosentan in routinely treated Japanese pediatric patients with pulmonary arterial hypertension.
Masato Taguchi, Fukiko Ichida, Keiichi Hirono, Toshio Miyawaki, Naoki Yoshimura, Yukiya Hashimoto

Drug Metab Pharmacokinet· June 2011

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Membrane transport mechanisms of quinidine and procainamide in renal LLC-PK1 and intestinal LS180 cells.
Miki Masago, Mari Takaai, Jumpei Sakata, Asuka Horie, Toshikazu Ito, Yukiya Hashimoto

Biol Pharm Bull· December 2010

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Inhibitory and stimulative effects of amiodarone on metabolism of carvedilol in human liver microsomes.
Isao Horiuchi, Yuya Kato, Arisa Nakamura, Kazuya Ishida, Masato Taguchi, Yukiya Hashimoto

Biol Pharm Bull· November 2010

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Temperature-dependent specific transport of levofloxacin in human intestinal epithelial LS180 cells.
Shiro Fukumori, Miki Masago, Kazuya Ishida, Yuichiro Kayano, Masato Taguchi, Yukiya Hashimoto

Biopharm Drug Dispos· November 2009

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Limited sampling strategy for patient-oriented clinical pharmacokinetic trial.
Yukiya Hashimoto

Drug Metab Pharmacokinet· October 2009

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Mechanisms responsible for the altered pharmacokinetics of bosentan: analysis utilizing rats with bile duct ligation-induced liver dysfunction.
Isao Horiuchi, Yun-I Mori, Masato Taguchi, Fukiko Ichida, Toshio Miyawaki, Yukiya Hashimoto

Biopharm Drug Dispos· September 2009

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A simulation study to evaluate limited sampling strategies to estimate area under the curve of drug concentration versus time following repetitive oral dosing: limited sampling model versus naive trapezoidal method.
Yuichiro Kayano, Isao Horiuchi, Yun-i Mori, Kazuya Ishida, Tomohisa Saito, Yukiya Hashimoto

Biol Pharm Bull· August 2009

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Membrane transport mechanisms of mizoribine in the rat intestine and human epithelial LS180 cells.
Kazuya Ishida, Mari Takaai, Ayano Yotsutani, Masato Taguchi, Yukiya Hashimoto

Biol Pharm Bull· April 2009

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Involvement of the CYP1A subfamily in stereoselective metabolism of carvedilol in beta-naphthoflavone-treated Caco-2 cells.
Kazuya Ishida, Masato Taguchi, Teruaki Akao, Yukiya Hashimoto

Biol Pharm Bull· March 2009

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