Publications by authors named "Yuko Hitomi"

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Design and Identification of a GPR40 Full Agonist () Possessing a 2-Carbamoylphenyl Piperidine Moiety.
Hideki Furukawa, Yasufumi Miyamoto, Yasuhiro Hirata, Koji Watanabe, Yuko Hitomi, Yayoi Yoshitomi

J Med Chem· September 2020

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Structure-based design of substituted piperidines as a new class of highly efficacious oral direct Renin inhibitors.
Takeru Ehara, Osamu Irie, Takatoshi Kosaka, Takanori Kanazawa, Werner Breitenstein, Yuko Hitomi

ACS Med Chem Lett· July 2014

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Overcoming hERG issues for brain-penetrating cathepsin S inhibitors: 2-cyanopyrimidines. Part 2.
Osamu Irie, Takatoshi Kosaka, Masashi Kishida, Junichi Sakaki, Keiichi Masuya, Yuko Hitomi

Bioorg Med Chem Lett· October 2008

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Effect of cathepsin K inhibitors on bone resorption.
Naoki Teno, Keiichi Masuya, Takeru Ehara, Takatoshi Kosaka, Takahiro Miyake, Yuko Hitomi

J Med Chem· September 2008

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Discovery of orally bioavailable cathepsin S inhibitors for the reversal of neuropathic pain.
Osamu Irie, Takatoshi Kosaka, Takeru Ehara, Fumiaki Yokokawa, Takanori Kanazawa, Yuko Hitomi

J Med Chem· September 2008

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4-Amino-2-cyanopyrimidines: novel scaffold for nonpeptidic cathepsin S inhibitors.
Osamu Irie, Fumiaki Yokokawa, Takeru Ehara, Atsuko Iwasaki, Yuki Iwaki, Yuko Hitomi

Bioorg Med Chem Lett· August 2008

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Discovery of selective and nonpeptidic cathepsin S inhibitors.
Osamu Irie, Takeru Ehara, Atsuko Iwasaki, Fumiaki Yokokawa, Junichi Sakaki, Yuko Hitomi

Bioorg Med Chem Lett· July 2008

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Novel scaffold for cathepsin K inhibitors.
Naoki Teno, Takahiro Miyake, Takeru Ehara, Osamu Irie, Junichi Sakaki, Yuko Hitomi

Bioorg Med Chem Lett· November 2007

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Divergent synthesis of L-sugars and L-iminosugars from D-sugars.
Hideyo Takahashi, Tomomi Shida, Yuko Hitomi, Yoshinori Iwai, Namisa Miyama

Chemistry· July 2006

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Novel synthesis of L-ribose from D-mannono-1,4-lactone.
Hideyo Takahashi, Yoshinori Iwai, Yuko Hitomi, Shiro Ikegami

Org Lett· July 2002

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