Publications by authors named "Yuriko Sobu"

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A mathematical model suggests collectivity and inconstancy enhance the efficiency of neuronal migration in the adult brain.
Daiki Wakita, Yuriko Sobu, Naoko Kaneko, Takeshi Kano

PLoS Comput Biol· June 2025

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Suppression of the amyloidogenic metabolism of APP and the accumulation of Aβ by alcadein α in the brain during aging.
Keiko Honda, Hiroo Takahashi, Saori Hata, Ruriko Abe, Takashi Saito, Yuriko Sobu

Sci Rep· August 2024

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Axonal transport of Frizzled5 by Alcadein α-containing vesicles is associated with kinesin-1.
Yuzuha Shiraki, Monet Mitsuma, Ritsuko Takada, Saori Hata, Akira Kitamura, Yuriko Sobu

Mol Biol Cell· October 2023

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Brain p3-Alcβ peptide restores neuronal viability impaired by Alzheimer's amyloid β-peptide.
Saori Hata, Haruka Saito, Takeharu Kakiuchi, Dai Fukumoto, Shigeyuki Yamamoto, Yuriko Sobu

EMBO Mol Med· May 2023

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Accumulation of amyloid-β in the brain of mouse models of Alzheimer's disease is modified by altered gene expression in the presence of human apoE isoforms during aging.
Keiko Honda, Yuhki Saito, Haruka Saito, Megumi Toyoda, Ruriko Abe, Yuriko Sobu

Neurobiol Aging· March 2023

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Measuring Axonal Cargo Transport in Mouse Primary Cortical Cultured Neurons.
Yuriko Sobu, Toshiharu Suzuki

J Vis Exp· February 2023

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γ-Secretase structure and activity are modified by alterations in its membrane localization and ambient environment.
Toshiharu Suzuki, Yuriko Sobu, Saori Hata

J Biochem· March 2022

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Suppression of amyloid-β secretion from neurons by cis-9, trans-11-octadecadienoic acid, an isomer of conjugated linoleic acid.
Saori Hata, Kuniyuki Kano, Kazunori Kikuchi, Shoichi Kinoshita, Yuriko Sobu

J Neurochem· November 2021

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Pathogenic LRRK2 control of primary cilia and Hedgehog signaling in neurons and astrocytes of mouse brain.
Shahzad S Khan, Yuriko Sobu, Herschel S Dhekne, Francesca Tonelli, Kerryn Berndsen

Elife· October 2021

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LRRK2-phosphorylated Rab10 sequesters Myosin Va with RILPL2 during ciliogenesis blockade.
Herschel S Dhekne, Izumi Yanatori, Edmundo G Vides, Yuriko Sobu, Federico Diez

Life Sci Alliance· May 2021

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Pathogenic LRRK2 regulates ciliation probability upstream of tau tubulin kinase 2 via Rab10 and RILPL1 proteins.
Yuriko Sobu, Paulina S Wawro, Herschel S Dhekne, Wondwossen M Yeshaw, Suzanne R Pfeffer

Proc Natl Acad Sci U S A· March 2021

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X11 and X11-like proteins regulate the level of extrasynaptic glutamate receptors.
Rika Motodate, Haruka Saito, Yuriko Sobu, Saori Hata, Yuhki Saito

J Neurochem· February 2019

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The cytoplasmic region of the amyloid β-protein precursor (APP) is necessary and sufficient for the enhanced fast velocity of APP transport by kinesin-1.
Maoko Tsukamoto, Kyoko Chiba, Yuriko Sobu, Yuzuha Shiraki, Yuka Okumura

FEBS Lett· August 2018

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Phosphorylation of multiple sites within an acidic region of Alcadein α is required for kinesin-1 association and Golgi exit of Alcadein α cargo.
Yuriko Sobu, Keiko Furukori, Kyoko Chiba, Angus C Nairn, Masataka Kinjo

Mol Biol Cell· December 2017

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Phosphorylation of KLC1 modifies interaction with JIP1 and abolishes the enhanced fast velocity of APP transport by kinesin-1.
Kyoko Chiba, Ko-Yi Chien, Yuriko Sobu, Saori Hata, Shun Kato

Mol Biol Cell· December 2017

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Facilitation of brain mitochondrial activity by 5-aminolevulinic acid in a mouse model of Alzheimer's disease.
Chiori Omori, Rika Motodate, Yuzuha Shiraki, Kyoko Chiba, Yuriko Sobu

Nutr Neurosci· November 2017

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Cytoplasmic fragment of Alcadein α generated by regulated intramembrane proteolysis enhances amyloid β-protein precursor (APP) transport into the late secretory pathway and facilitates APP cleavage.
Norio Takei, Yuriko Sobu, Ayano Kimura, Satomi Urano, Yi Piao

J Biol Chem· January 2015

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