Publications by authors named "Yusu Gu"

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AAV-TNNI3 rescues an experimental murine Tnni3 mutation resulting in thin filament mediated DCM.
Paul J Bushway, Wei Feng, Marina Sampaio De Menezes Cruz, Sofie Maisel, Aysen Shathaya, Betul Gunes, Eren Gunes, Yusu Gu

J Mol Cell Cardiol· January 2026

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Transcription regulation by TBX18 in smooth muscle cells is essential for normal aortic development and homeostasis.
Debanjan Mukherjee, Veronica Larcher, Hanna Winter, Nadja Sachs, Francesca Andriani, Yusu Gu, Nuno Guimarães-Camboa

Cardiovasc Res· December 2025

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ASNA1 is essential for cardiac development and function by regulating tail-anchored protein stability and vesicular transport in cardiomyocytes.
Wei Feng, Zengming Zhang, Zeyu Chen, Li Wang, Mao Ye, Yusu Gu

PLoS Genet· December 2025

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Human Variant in the Cardiac Troponin I Switch Domain Causes Diastolic Dysfunction in a Novel Mouse Model.
Elizabeth Silver, Jason M Duran, Betul Beyza Gunes, Axel J Fenwick, Sofie Maisel, Yusu Gu

J Am Heart Assoc· November 2025

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A Novel miniALPK3 Gene Therapy for ALPK3-Associated Cardiomyopathy.
Wei Feng, Julijus Bogomolovas, Abraham Grant Shain, Li Wang, Chao Chen, Yusu Gu

Circulation· November 2025

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Overlapping functions between and in cardiac autophagy.
Marina Sampaio Cruz, Ana Maria Manso, Angel Soto-Hermida, Paul Bushway, Elizabeth Silver, Betul Beyza Gunes, Liguo Chi, Yusu Gu, Asa B Gustafsson

Autophagy· September 2025

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RBPMS and RBPMS2 Cooperate to Safeguard Cardiac Splicing.
Tongbin Wu, Zeyu Chen, Chao Gao, Elise V Stanley, Zengming Zhang, Yusu Gu

Circ Res· September 2025

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Combined Loss of Obsc and Obsl1 in Murine Hearts Results in Diastolic Dysfunction, Altered Metabolism, and Deregulated Mitophagy.
Kyohei Fujita, Patrick Desmond, Jordan Blondelle, Matúš Soták, Meenu Rohini Rajan, Yusu Gu

Circ Heart Fail· April 2025

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α Protein Kinase 3 Is Essential for Neonatal and Adult Cardiac Function.
Wei Feng, Li Wang, Julius Bogomolovas, Zengming Zhang, Titania Huang, Yusu Gu

J Am Heart Assoc· April 2025

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Loss of GATAD1 in cardiomyocyte does not cause cardiomyopathy in mice.
Jing Pang, Siting Zhu, Melody Shyy, Janelle Duong, Tiana Tran, Yusu Gu

J Mol Histol· December 2024

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RBPMS and RBPMS2 Cooperate to Safeguard Cardiac Splicing.
Tongbin Wu, Zeyu Chen, Zengming Zhang, Xiaohai Zhou, Yusu Gu

bioRxiv· November 2024

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Dietary linoleic acid supplementation fails to rescue established cardiomyopathy in Barth syndrome.
Siting Zhu, Jing Pang, Anh Nguyen, Helen Huynh, Sharon Lee, Yusu Gu

J Mol Cell Cardiol Plus· June 2024

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Temporal Effects of Safflower Oil Diet-Based Linoleic Acid Supplementation on Barth Syndrome Cardiomyopathy.
Siting Zhu, Jing Pang, Anh Nguyen, Changming Tan, Alexandria Tso, Yusu Gu, Asa B Gustafsson

Circulation· March 2024

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Plakophilin 2 gene therapy prevents and rescues arrhythmogenic right ventricular cardiomyopathy in a mouse model harboring patient genetics.
William H Bradford, Jing Zhang, Erika J Gutierrez-Lara, Yan Liang, Aryanne Do, Lena Nguyen, Yusu Gu

Nat Cardiovasc Res· December 2023

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Interaction of Filamin C With Actin Is Essential for Cardiac Development and Function.
Xiaohai Zhou, Xi Fang, Sujay Subbayya Ithychanda, Tongbin Wu, Yusu Gu

Circ Res· August 2023

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DELE1 is protective for mitochondrial cardiomyopathy.
Helen Huynh, Siting Zhu, Sharon Lee, Yutong Bao, Jing Pang, Anh Nguyen, Yusu Gu

J Mol Cell Cardiol· February 2023

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Increasing Mononuclear Diploid Cardiomyocytes by Loss of E2F Transcription Factor 7/8 Fails to Improve Cardiac Regeneration After Infarct.
Zhe Yu, Lunfeng Zhang, Paola Cattaneo, Nuno Guimarães-Camboa, Xi Fang, Yusu Gu, Gustavo W Leone

Circulation· January 2023

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Mitochondrial Stress Induces an HRI-eIF2α Pathway Protective for Cardiomyopathy.
Siting Zhu, Anh Nguyen, Jing Pang, Jun Zhao, Ze'e Chen, Yusu Gu

Circulation· September 2022

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Constitutive protein kinase G activation exacerbates stress-induced cardiomyopathy.
Gerburg K Schwaerzer, Darren E Casteel, Federico Cividini, Hema Kalyanaraman, Shunhui Zhuang, Yusu Gu

Br J Pharmacol· June 2022

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PRDM16 Is a Compact Myocardium-Enriched Transcription Factor Required to Maintain Compact Myocardial Cardiomyocyte Identity in Left Ventricle.
Tongbin Wu, Zhengyu Liang, Zengming Zhang, Canzhao Liu, Lunfeng Zhang, Yusu Gu

Circulation· February 2022

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Mediator complex proximal Tail subunit MED30 is critical for Mediator core stability and cardiomyocyte transcriptional network.
Changming Tan, Siting Zhu, Zee Chen, Canzhao Liu, Yang E Li, Yusu Gu

PLoS Genet· September 2021

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PTPMT1 Is Required for Embryonic Cardiac Cardiolipin Biosynthesis to Regulate Mitochondrial Morphogenesis and Heart Development.
Ze'e Chen, Siting Zhu, Hong Wang, Li Wang, Jianlin Zhang, Yusu Gu

Circulation· August 2021

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Desmosomal COP9 regulates proteome degradation in arrhythmogenic right ventricular dysplasia/cardiomyopathy.
Yan Liang, Robert C Lyon, Jason Pellman, William H Bradford, Stephan Lange, Yusu Gu

J Clin Invest· June 2021

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Cardiolipin Remodeling Defects Impair Mitochondrial Architecture and Function in a Murine Model of Barth Syndrome Cardiomyopathy.
Siting Zhu, Ze'e Chen, Mason Zhu, Ying Shen, Leonardo J Leon, Liguo Chi, Yusu Gu, Anh Nguyen, Asa B Gustafsson

Circ Heart Fail· June 2021

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Suppression of Endothelial AGO1 Promotes Adipose Tissue Browning and Improves Metabolic Dysfunction.
Xiaofang Tang, Yifei Miao, Yingjun Luo, Kiran Sriram, Zhijie Qi, Yusu Gu

Circulation· July 2020

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