Publications by authors named "Yusuke Amanuma"

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The FSTL1-DIP2A axis is a significant biomarker for predicting anti-PD1 therapeutic efficacy in advanced gastric cancer.
Chie Kudo-Saito, Hiroshi Imazeki, Kengo Nagashima, Hirokazu Shoji, Kai Tsugaru, Yusuke Amanuma

Cancer Immunol Immunother· November 2025

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IL33-ST2 axis is a predictive biomarker for anti-PD1 therapeutic efficacy in advanced gastric cancer.
Chie Kudo-Saito, Hiroshi Imazeki, Kengo Nagashima, Hirokazu Shoji, Kai Tsugaru, Yusuke Amanuma

J Transl Med· October 2025

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Peripheral SNCA cells as a poor prognostic factor for nivolumab therapy in advanced gastric cancer.
Chie Kudo-Saito, Hiroshi Imazeki, Kengo Nagashima, Hirokazu Shoji, Kai Tsugaru, Yusuke Amanuma

Discov Oncol· October 2025

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Phase II trial of nab-paclitaxel plus ramucirumab in combination with nivolumab for unresectable advanced or recurrent gastric cancer after progression on first-line treatment including fluoropyrimidine, platinum, and anti-PD-1/PD-L1 antibody (PADDLE).
Hidekazu Hirano, Naoki Takahashi, Yusuke Amanuma, Nobumi Suzuki, Daisuke Takahari

BMC Cancer· February 2025

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Myeloid subsets impede the efficacy of anti-PD1 therapy in patients with advanced gastric cancer (WJOG10417GTR study).
Hirokazu Shoji, Chie Kudo-Saito, Kengo Nagashima, Hiroshi Imazeki, Kai Tsugaru, Yusuke Amanuma

J Immunother Cancer· November 2024

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Effectiveness of taxanes following nivolumab in patients with advanced esophageal squamous cell carcinoma: a retrospective chart review of patients in ATTRACTION-3.
Keisho Chin, Shun Yamamoto, Masanobu Takahashi, Shigenori Kadowaki, Yutaro Kubota, Yusuke Amanuma

Esophagus· April 2023

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Pattern of disease progression during third-line or later chemotherapy with nivolumab associated with poor prognosis in advanced gastric cancer: a multicenter retrospective study in Japan.
Masahiko Aoki, Shigenori Kadowaki, Naoki Takahashi, Takeshi Suzuki, Kotoe Oshima, Yusuke Amanuma

Gastric Cancer· January 2023

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An exploration of trifluridine/tipiracil in combination with irinotecan in patients with pretreated advanced gastric cancer.
Takuro Mizukami, Keiko Minashi, Hiroki Hara, Tomohiro Nishina, Yusuke Amanuma

Invest New Drugs· June 2022

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Repeated talaporfin sodium photodynamic therapy for esophageal cancer: safety and efficacy.
Masashi Tamaoki, Akira Yokoyama, Takahiro Horimatsu, Kenshiro Hirohashi, Yusuke Amanuma

Esophagus· October 2021

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Association of local complete response with prognosis after salvage photodynamic therapy for esophageal squamous cell carcinoma.
Yusuke Amanuma, Takahiro Horimatsu, Shinya Ohashi, Masashi Tamaoki, Manabu Muto

Dig Endosc· March 2021

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Protective effects of Alda-1, an ALDH2 activator, on alcohol-derived DNA damage in the esophagus of human ALDH2*2 (Glu504Lys) knock-in mice.
Kenshiro Hirohashi, Shinya Ohashi, Yusuke Amanuma, Yukie Nakai, Tomomi Ida

Carcinogenesis· April 2020

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Successful Neurological Recovery with Multimodality Therapy without Surgery for Spinal Metastases from Advanced Gastric Cancer.
Hideyuki Kinoshita, Hiroto Kamoda, Takeshi Ishii, Yoko Hagiwara, Toshinori Tsukanishi, Yusuke Amanuma

Case Rep Orthop· February 2020

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Age-related remodelling of oesophageal epithelia by mutated cancer drivers.
Akira Yokoyama, Nobuyuki Kakiuchi, Tetsuichi Yoshizato, Yasuhito Nannya, Hiromichi Suzuki, Yusuke Amanuma

Nature· January 2019

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Molecular Mechanisms of Acetaldehyde-Mediated Carcinogenesis in Squamous Epithelium.
Ayaka Mizumoto, Shinya Ohashi, Kenshiro Hirohashi, Yusuke Amanuma, Tomonari Matsuda

Int J Mol Sci· September 2017

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Distinct effects of EGFR inhibitors on epithelial- and mesenchymal-like esophageal squamous cell carcinoma cells.
Masahiro Yoshioka, Shinya Ohashi, Tomomi Ida, Yukie Nakai, Osamu Kikuchi, Yusuke Amanuma

J Exp Clin Cancer Res· August 2017

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Establishment of a Quick and Highly Accurate Breath Test for ALDH2 Genotyping.
Ikuo Aoyama, Shinya Ohashi, Yusuke Amanuma, Kenshiro Hirohashi, Ayaka Mizumoto

Clin Transl Gastroenterol· June 2017

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Alcohol Consumption and Multiple Dysplastic Lesions Increase Risk of Squamous Cell Carcinoma in the Esophagus, Head, and Neck.
Chikatoshi Katada, Tetsuji Yokoyama, Tomonori Yano, Kazuhiro Kaneko, Ichiro Oda, Yusuke Amanuma

Gastroenterology· November 2016

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ALDH2 modulates autophagy flux to regulate acetaldehyde-mediated toxicity thresholds.
Koji Tanaka, Kelly A Whelan, Prasanna M Chandramouleeswaran, Shingo Kagawa, Sabrina L Rustgi, Yusuke Amanuma

Am J Cancer Res· May 2016

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Recent Advances From Basic and Clinical Studies of Esophageal Squamous Cell Carcinoma.
Shinya Ohashi, Shin'ichi Miyamoto, Osamu Kikuchi, Tomoyuki Goto, Yusuke Amanuma

Gastroenterology· December 2015

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Serum miR-21, miR-29a, and miR-125b Are Promising Biomarkers for the Early Detection of Colorectal Neoplasia.
Atsushi Yamada, Takahiro Horimatsu, Yoshinaga Okugawa, Naoshi Nishida, Hajime Honjo, Yusuke Amanuma

Clin Cancer Res· September 2015

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Protective role of ALDH2 against acetaldehyde-derived DNA damage in oesophageal squamous epithelium.
Yusuke Amanuma, Shinya Ohashi, Yoshiro Itatani, Mihoko Tsurumaki, Shun Matsuda

Sci Rep· September 2015

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Novel 5-fluorouracil-resistant human esophageal squamous cell carcinoma cells with dihydropyrimidine dehydrogenase overexpression.
Osamu Kikuchi, Shinya Ohashi, Yukie Nakai, Shunsaku Nakagawa, Kazuaki Matsuoka, Yusuke Amanuma

Am J Cancer Res· September 2015

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Impairment of aldehyde dehydrogenase 2 increases accumulation of acetaldehyde-derived DNA damage in the esophagus after ethanol ingestion.
Yoshiyuki Yukawa, Shinya Ohashi, Yusuke Amanuma, Yukie Nakai, Mihoko Tsurumaki

Am J Cancer Res· June 2014

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