Publications by authors named "Yusuke Isshiki"

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Mutant EZH2 alters the epigenetic network and increases epigenetic heterogeneity in B cell lymphoma.
Ofir Griess, Noa Furth, Nofar Harpaz, Nicoletta Di Bernardo, Tomer-Meir Salame, Yusuke Isshiki

PLoS Biol· June 2025

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EZH1/EZH2 inhibition enhances adoptive T cell immunotherapy against multiple cancer models.
Patrizia Porazzi, Siena Nason, Ziqi Yang, Alberto Carturan, Guido Ghilardi, Yusuke Isshiki

Cancer Cell· March 2025

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EZH2 inhibition enhances T cell immunotherapies by inducing lymphoma immunogenicity and improving T cell function.
Yusuke Isshiki, Xi Chen, Matt Teater, Ioannis Karagiannidis, Henna Nam

Cancer Cell· January 2025

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Detection of clonal plasma cells in POEMS syndrome using multiparameter flow cytometry.
Arata Ishii, Shokichi Tsukamoto, Naoya Mimura, Yurie Miyamoto-Nagai, Yusuke Isshiki

Sci Rep· May 2024

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The pathogenetic significance of exhausted T cells in a mouse model of mature B cell neoplasms.
Asuka Shibamiya, Yurie Miyamoto-Nagai, Shuhei Koide, Motohiko Oshima, Ola Rizq, Yusuke Isshiki

Cancer Immunol Immunother· August 2023

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[Identification of transcriptional features and surface markers of plasma cell clones in POEMS syndrome by single-cell RNA sequencing].
Yusuke Isshiki, Motohiko Oshima, Naoya Mimura, Emiko Sakaida, Atsushi Iwama

Rinsho Ketsueki· August 2023

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Polycomb repressive complex 1.1 coordinates homeostatic and emergency myelopoiesis.
Yaeko Nakajima-Takagi, Motohiko Oshima, Junichiro Takano, Shuhei Koide, Naoki Itokawa, Yusuke Isshiki

Elife· June 2023

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An Aged/Autoimmune B-cell Program Defines the Early Transformation of Extranodal Lymphomas.
Leandro Venturutti, Martin A Rivas, Benedikt W Pelzer, Ruth Flümann, Julia Hansen, Yusuke Isshiki

Cancer Discov· January 2023

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Unraveling unique features of plasma cell clones in POEMS syndrome with single-cell analysis.
Yusuke Isshiki, Motohiko Oshima, Naoya Mimura, Kensuke Kayamori, Yurie Miyamoto-Nagai

JCI Insight· October 2022

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Epigenetic, Metabolic, and Immune Crosstalk in Germinal-Center-Derived B-Cell Lymphomas: Unveiling New Vulnerabilities for Rational Combination Therapies.
Inna Serganova, Sanjukta Chakraborty, Samuel Yamshon, Yusuke Isshiki, Ryan Bucktrout

Front Cell Dev Biol· January 2022

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Epigenetic Mechanisms of Therapy Resistance in Diffuse Large B Cell Lymphoma (DLBCL).
Yusuke Isshiki, Ari Melnick

Curr Cancer Drug Targets· December 2021

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[A Case Report of Cancer Chemotherapy for Disseminated Carcinomatosis of the Bone Marrow Associated with Gastric Cancer Accompanied by Disseminated Intravascular Coagulation].
Ryotaro Eto, Satoshi Ambiru, Hiroyuki Yoshidome, Terumi Itabashi, Seiji Furuya, Yusuke Isshiki

Gan To Kagaku Ryoho· March 2021

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The combination of the tubulin binding small molecule PTC596 and proteasome inhibitors suppresses the growth of myeloma cells.
Yurie Nagai, Naoya Mimura, Ola Rizq, Yusuke Isshiki, Motohiko Oshima

Sci Rep· January 2021

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Suppressive effects of anagrelide on cell cycle progression and the maturation of megakaryocyte progenitor cell lines in human induced pluripotent stem cells.
Koji Takaishi, Masahiro Takeuchi, Shokichi Tsukamoto, Naoya Takayama, Motohiko Oshima, Yusuke Isshiki

Haematologica· May 2020

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Remarkable donor-derived T cell lymphocytosis before engraftment of a bone marrow transplant for acute lymphoblastic leukemia.
Yurie Nagai, Shokichi Tsukamoto, Yutaro Hino, Yusuke Isshiki, Miki Yamazaki

Leuk Lymphoma· January 2020

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Akt inhibition synergizes with polycomb repressive complex 2 inhibition in the treatment of multiple myeloma.
Mohamed Rizk, Ola Rizq, Motohiko Oshima, Yaeko Nakajima-Takagi, Shuhei Koide, Yusuke Isshiki

Cancer Sci· December 2019

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KDM2B in polycomb repressive complex 1.1 functions as a tumor suppressor in the initiation of T-cell leukemogenesis.
Yusuke Isshiki, Yaeko Nakajima-Takagi, Motohiko Oshima, Kazumasa Aoyama, Mohamed Rizk

Blood Adv· September 2019

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Immunomodulator-associated Epstein-Barr virus-positive mucocutaneous ulcer in a patient with refractory Crohn's disease.
Shinsaku Hamanaka, Tomoo Nakagawa, Satoshi Ota, Mana Iida, Yuki Ohta, Yusuke Isshiki

Clin J Gastroenterol· August 2019

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Bmi1 restricts the adipogenic differentiation of bone marrow stromal cells to maintain the integrity of the hematopoietic stem cell niche.
Yuko Kato, Li-Bo Hou, Satoru Miyagi, Eriko Nitta, Kazumasa Aoyama, Yusuke Isshiki

Exp Hematol· August 2019

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Genetic and transcriptional landscape of plasma cells in POEMS syndrome.
Yuhei Nagao, Naoya Mimura, June Takeda, Kenichi Yoshida, Yusuke Shiozawa, Yusuke Isshiki

Leukemia· July 2019

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Low incidence of thromboembolism in multiple myeloma patients receiving immunomodulatory drugs; a retrospective single-institution analysis.
Koji Takaishi, Shokichi Tsukamoto, Chikako Ohwada, Masahiro Takeuchi, Yohei Kawasaki, Yusuke Isshiki

J Thromb Thrombolysis· July 2019

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T315I mutation with lymphoblasts in a newly diagnosed patient with chronic-phase chronic myeloid leukemia.
Kenji Kimura, Shokichi Tsukamoto, Koji Takaishi, Yusuke Isshiki, Kensuke Kayamori

Leuk Lymphoma· June 2019

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insufficiency promotes initiation and progression of myelodysplastic syndrome.
Shiro Tara, Yusuke Isshiki, Yaeko Nakajima-Takagi, Motohiko Oshima, Kazumasa Aoyama

Blood· December 2018

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Emerging role of noncanonical polycomb repressive complexes in normal and malignant hematopoiesis.
Yusuke Isshiki, Atsushi Iwama

Exp Hematol· December 2018

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Multiple cystic lung lesions and autoimmune thrombocytopaenia developing after chemotherapy for pulmonary indolent B-cell lymphoma with plasmacytic differentiation.
Hiroaki Tanaka, Chihiro Kuwabara, Yusuke Isshiki, Yoshio Suzuki

BMJ Case Rep· December 2018

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