Publications by authors named "Yusun Lee"

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A systemic evaluation of the effect of dsRNA contamination on mRNA vaccine expression and immunogenicity.
Sohee Jo, Jisun Lee, Sang-In Park, Yoonseob Kim, Subin Yoon, Seonghyun Lee, Yeeun Lee, Sowon Lee, Soo-Yeon Lee, Yu-Sun Lee

J Control Release· January 2026

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Designing 5' UTR sequences improves the capacity of mRNA therapeutics in preclinical models of aging and obesity.
Subin Yoon, Hyeonggon Cho, Jisun Lee, Sunghyun Ha, Suyeon Lee, Yu-Sun Lee, Seonghyun Lee, Young-Suk Lee

Mol Ther· January 2026

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Design and immunogenicity of a quadrivalent mRNA vaccine targeting HSV-2 with comparative evaluation of co-formulated and admixed formulations.
Youngran Cho, Chanwoo Lee, Sang-In Park, Yeongjun Kim, Yu-Sun Lee, Seonghyun Lee, Jisun Lee, Hye-Ra Lee

Front Immunol· December 2025

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Integration of TLR7/8 agonists into lipid nanoparticles enhances antigen-specific immune responses to N1-methyl-Ψ-modified mRNA-LNP vaccines.
Huijeong Choi, Seonghyun Lee, Hyejin Kim, Seo-Hyeon Bae, Sohee Jo, Yeeun Lee, Yu-Sun Lee, Sowon Lee, Jisun Lee

J Biol Eng· November 2025

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Rapid-Turnaround Co-Administration of mRNA-Based MHC-I and MHC-II-Restricted Neoantigens Enhances Immune Responses of Antigen-Specific CD8 T Cells and Anti-Cancer Efficacy in Colorectal Cancer.
Seongje Cho, Woori Kwak, Hyunho Yoon, Jisun Lee, Seonghyun Lee, Yu-Sun Lee, Soo-Yeon Lee, Yeeun Lee, Sowon Lee

Adv Sci (Weinh)· October 2025

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Effective mRNA-based therapy using E7 antigen and IL-12 cytokine in head and neck cancer mice models.
Seonghyun Lee, Jisun Lee, Yu-Sun Lee, Sowon Lee, Subin Yoon, Soo-Yeon Lee, Yeeun Lee

Vaccine· October 2025

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ApoE deficiency protects from mRNA vaccine-induced mitochondrial dysfunction at the injection site under metabolic stress.
Sun-Hee Cho, Byeongkwon Choi, Jisun Lee, Yu-Sun Lee, Mi-Ock Baek, You-Jeung Lee, Sowon Lee, Seonghyun Lee, Na-Young Lee

Theranostics· September 2025

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Comparative immunologic profiling of mRNA and protein-conjugated vaccines: acute inflammatory responses and anti-PEG antibody production.
Gahyun Roh, Jisun Lee, Hyun-Mee Park, Woori Kwak, Hyo-Jung Park, Yu-Sun Lee, Seonghyun Lee, Sowon Lee, Jacob Lee

Anim Cells Syst (Seoul)· June 2025

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Organoid morphology-guided classification for oral cancer reveals prognosis.
Mi Rim Lee, Sumin Kang, Jonghyun Lee, Sun-Young Kong, Youngwook Kim, Yu-Sun Lee, Jiyoung Lee, Jong-Ho Lee

Cell Rep Med· May 2025

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ATR inhibition promotes synergistic antitumor effect in platinum-resistant pancreatic cancer.
Jung Won Chun, Hye Won Shon, Jeong Eun Gong, Mi Rim Lee, Yu-Sun Lee, Kyung Yong Lee, Woo Jin Lee, Sang Hyub Lee

Biochim Biophys Acta Mol Basis Dis· March 2025

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Rational Design of Lipid Nanoparticles for Enhanced mRNA Vaccine Delivery via Machine Learning.
Seo-Hyeon Bae, Hosam Choi, Jisun Lee, Min-Ho Kang, Seong-Ho Ahn, Yu-Sun Lee, Yeeun Lee, Seonghyun Lee, Soo-Yeon Lee, Sowon Lee, Nakyung Lee, Minyoung Lee, Kiyoun Lee

Small· February 2025

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Immunogenicity and protection of a triple repeat domain III mRNA vaccine against Zika virus.
Yu-Sun Lee, Mi Sun Cheong, Jisun Lee, Eun-Kyoung Bang, Sang In Park, Seonghyun Lee, Soo-Yeon Lee, Yeeun Lee, Dabin Lee

Vaccine· January 2025

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SARS-CoV2 mRNA vaccine intravenous administration induces myocarditis in chronic inflammation.
Ha-Eun Jeon, Seonghyun Lee, Jisun Lee, Gahyun Roh, Hyo-Jung Park, Yu-Sun Lee, You-Jeung Lee

PLoS One· October 2024

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A lipid nanoparticle platform incorporating trehalose glycolipid for exceptional mRNA vaccine safety.
Seo-Hyeon Bae, Soyeon Yoo, Jisun Lee, Hyo-Jung Park, Sung Pil Kwon, Yu-Sun Lee, Seonghyun Lee

Bioact Mater· August 2024

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Analysis of the Immunostimulatory Effects of Cytokine-Expressing Internal Ribosome Entry Site-Based RNA Adjuvants and Their Applications.
Yu-Sun Lee, Yoo-Jin Bang, Soyeon Yoo, Sang-In Park, Hyo-Jung Park, Seonghyun Lee

J Infect Dis· May 2024

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New Function Annotation of PROSER2 in Pancreatic Ductal Adenocarcinoma.
Yu-Sun Lee, Jieun Im, Yeji Yang, Hea Ji Lee, Mi Rim Lee

J Proteome Res· March 2024

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Assessing the impact of mRNA vaccination in chronic inflammatory murine model.
Seonghyun Lee, Jisun Lee, Sun-Hee Cho, Gahyun Roh, Hyo-Jung Park, You-Jeung Lee, Yu-Sun Lee, Soo-Yeon Lee, Sowon Lee

NPJ Vaccines· February 2024

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mRNA-HPV vaccine encoding E6 and E7 improves therapeutic potential for HPV-mediated cancers via subcutaneous immunization.
Seonghyun Lee, Hyunho Yoon, Seol Hee Hong, Sung Pil Kwon, Jung Joo Hong, Jisun Lee, Yu-Sun Lee, Sowon Lee, Soo-Yeon Lee, Shee Eun Lee

J Med Virol· December 2023

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Complexation of drug and hapten-conjugated aptamer with universal hapten antibody for pancreatic cancer treatment.
Sun Il Choi, Yu-Sun Lee, Yul Min Lee, Hyun Jung Kim, Won Jong Kim, Mi Rim Lee

J Control Release· August 2023

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Heterologous vaccination utilizing viral vector and protein platforms confers complete protection against SFTSV.
Jae-Yong Kim, Kyeongseok Jeon, Jung Joo Hong, Sang-In Park, Hyeonggon Cho, Yu-Sun Lee, Hwal-Yong Lee, Joo-Yeon Lee, Sang-Myeong Lee, Young-Suk Lee

Sci Rep· May 2023

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Single-stranded RNA adjuvant enhances the efficacy of 10-valent human papilloma virus-like particle vaccine.
Hye Won Kwak, Wooseok Shin, Kyunghwa Baik, Minsun Kim, YongWook Park, Yu-Sun Lee

Microbiol Immunol· November 2022

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Adjuvant effect of IRES-based single-stranded RNA on melanoma immunotherapy.
Hye Won Kwak, So-Hee Hong, Hyo-Jung Park, Hyeong-Jun Park, Yoo-Jin Bang, Yu-Sun Lee

BMC Cancer· October 2022

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Real-World Safety and Effectiveness of Denosumab in Patients with Osteoporosis: A Prospective, Observational Study in South Korea.
Yumie Rhee, Dong-Gune Chang, Jeonghoon Ha, Sooa Kim, Yusun Lee

Endocrinol Metab (Seoul)· June 2022

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Comparison of remission criteria in patients with rheumatoid arthritis treated with biologic or targeted synthetic disease-modifying anti-rheumatic drugs: results from a nationwide registry.
Jung Hee Koh, Yusun Lee, Hyoun-Ah Kim, Jinhyun Kim, Kichul Shin

Ther Adv Musculoskelet Dis· May 2022

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Risk of Acute Anterior Uveitis in Ankylosing Spondylitis According to the Type of Tumor Necrosis Factor-Alpha Inhibitor and History of Uveitis: A Nationwide Population-Based Study.
Soo Min Ahn, Minju Kim, Ye-Jee Kim, Yusun Lee, Yong-Gil Kim

J Clin Med· January 2022

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