Publications by authors named "Yuta Mitobe"

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Efficient Inhibition of FOXM1 Expression and Viability of High-grade Meningioma Cells by Domatinostat-mediated Dual Targeting of HDAC1 and HDAC2.
Kazuki Nakamura, Yasufumi Ito, Yurika Nakagawa-Saito, Senri Takenouchi, Shuhei Suzuki, Yuta Mitobe

Anticancer Res· November 2025

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Senolytic Elimination of Senescent Ovarian Clear Cell Carcinoma Cells Induced by CEP-1347 With the BH3 Mimetic Navitoclax.
Yasufumi Ito, Kazuki Nakamura, Yurika Nakagawa-Saito, Senri Takenouchi, Shuhei Suzuki, Yuta Mitobe

Anticancer Res· November 2025

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Association of Postoperative Delirium and Perioperative Factors With Frailty in Laparoscopic Gastrointestinal Surgery: A Retrospective Observational Study.
Naoko Tachibana, Yuta Mitobe, Fukuyo Taichi

Cureus· October 2025

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Effects of Motor-Evoked Potential Monitoring During Spine Surgery on the Length of Hospital Stay and Postoperative Acute Pain.
Fukuyo Taichi, Yuta Mitobe, Yasuko Baba, Naoko Tachibana, Tetsuya Miyashita

Cureus· September 2025

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HDAC Class I Inhibitor Domatinostat Induces Apoptosis Preferentially in Glioma Stem Cells Through p53-Dependent and -Independent Activation of BAX Expression.
Yurika Nakagawa-Saito, Yasufumi Ito, Kazuki Nakamura, Yuta Mitobe, Keita Togashi

Int J Mol Sci· August 2025

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Effective Targeting of Glioma Stem Cells by BSJ-04-122, a Novel Covalent MKK4/7 Dual Inhibitor.
Kazuki Nakamura, Yasufumi Ito, Senri Takenouchi, Yurika Nakagawa-Saito, Shuhei Suzuki, Yuta Mitobe

Anticancer Res· July 2025

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Targeting Bcl-xL with Navitoclax Effectively Eliminates Senescent Tumor Cells That Appear Following CEP-1347-Induced Differentiation of Glioma Stem Cells.
Senri Takenouchi, Yasufumi Ito, Kazuki Nakamura, Yurika Nakagawa-Saito, Yuta Mitobe

Int J Mol Sci· July 2025

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Association Between Intraoperative Hypothermia and Preoperative Body Composition in Patients Undergoing General Anesthesia for Gastrointestinal Surgery.
Shuta Sugiyama, Yuta Mitobe, Moe Sakata, Kenta Akitsu

Cureus· July 2025

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Efficacy and safety of carmustine wafers, followed by radiation, temozolomide, and bevacizumab therapy, for newly diagnosed glioblastoma with maximal resection.
Masayuki Kanamori, Ichiyo Shibahara, Yoshiteru Shimoda, Yukinori Akiyama, Takaaki Beppu, Yuta Mitobe

Int J Clin Oncol· January 2025

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The Influence of Total Fat Mass and Skeletal Muscle Mass Index on the Occurrence of Perioperative Hypothermia in Patients Undergoing Open Gastrectomy.
Ayako Amada, En Amada, Yuta Mitobe, Souya Nunobe, Yoshimi Inagaki

Yonago Acta Med· November 2024

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Cost of medical care for malignant brain tumors at hospitals in the Japan Clinical Oncology Group brain-tumor study group.
Kazuya Motomura, Keita Sasaki, Narushi Sugii, Shigeru Yamaguchi, Hirotaka Inoue, Yuta Mitobe

Jpn J Clin Oncol· October 2024

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Correction: Neuroradiological, genetic and clinical characteristics of histone H3 K27-mutant diffuse midline gliomas in the Kansai Molecular Diagnosis Network for CNS Tumors (Kansai Network): multicenter retrospective cohort.
Nobuhide Hayashi, Junya Fukai, Hirokazu Nakatogawa, Hiroshi Kawaji, Ema Yoshioka, Yuta Mitobe

Acta Neuropathol Commun· October 2024

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CEP-1347 Boosts Chk2-Mediated p53 Activation by Ionizing Radiation to Inhibit the Growth of Malignant Brain Tumor Cells.
Yuta Mitobe, Shuhei Suzuki, Kazuki Nakamura, Yurika Nakagawa-Saito, Senri Takenouchi

Int J Mol Sci· August 2024

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Neuroradiological, genetic and clinical characteristics of histone H3 K27-mutant diffuse midline gliomas in the Kansai Molecular Diagnosis Network for CNS Tumors (Kansai Network): multicenter retrospective cohort.
Nobuhide Hayashi, Junya Fukai, Hirokazu Nakatogawa, Hiroshi Kawaji, Ema Yoshioka, Yuta Mitobe

Acta Neuropathol Commun· July 2024

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The MDM2-p53 Axis Represents a Therapeutic Vulnerability Unique to Glioma Stem Cells.
Yurika Nakagawa-Saito, Yuta Mitobe, Keita Togashi, Shuhei Suzuki, Asuka Sugai

Int J Mol Sci· April 2024

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Association of ADC of hyperintense lesions on FLAIR images with TERT promoter mutation status in glioblastoma IDH wild type.
Shigeru Kamimura, Yuta Mitobe, Kazuki Nakamura, Kenichiro Matsuda, Yonehiro Kanemura

Surg Neurol Int· March 2024

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CEP-1347 Dually Targets MDM4 and PKC to Activate p53 and Inhibit the Growth of Uveal Melanoma Cells.
Keita Togashi, Shuhei Suzuki, Yuta Mitobe, Yurika Nakagawa-Saito, Asuka Sugai

Cancers (Basel)· December 2023

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Antagonizing MDM2 Overexpression Induced by MDM4 Inhibitor CEP-1347 Effectively Reactivates Wild-Type p53 in Malignant Brain Tumor Cells.
Yuta Mitobe, Shuhei Suzuki, Yurika Nakagawa-Saito, Keita Togashi, Asuka Sugai

Cancers (Basel)· August 2023

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The Novel MDM4 Inhibitor CEP-1347 Activates the p53 Pathway and Blocks Malignant Meningioma Growth In Vitro and In Vivo.
Yuta Mitobe, Shuhei Suzuki, Yurika Nakagawa-Saito, Keita Togashi, Asuka Sugai

Biomedicines· July 2023

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Preoperative Risk Factors in Patients With Pancreatic Cancer.
Naomi Kusama, Yuta Mitobe, Natsuko Hyodo, Tetsuya Miyashita, Yasuko Baba

J Clin Med Res· June 2023

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Domatinostat Targets the FOXM1-Survivin Axis to Reduce the Viability of Ovarian Cancer Cells Alone and in Combination with Chemotherapeutic Agents.
Yurika Nakagawa-Saito, Yuta Mitobe, Shuhei Suzuki, Keita Togashi, Asuka Sugai

Int J Mol Sci· June 2023

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Differences in Analgesia Methods for Open Gastrointestinal Surgery Are Not Associated With Initial Postoperative Ambulation.
Yuta Mitobe, Takeshi Itou, Yuri Yamaguchi, Tomomi Yoshioka, Kenji Nakagawa

J Clin Med Res· May 2023

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Predictors of Catheter-Related Bladder Discomfort After Surgery: A Literature Review.
Yuta Mitobe, Tomomi Yoshioka, Yasuko Baba, Yuri Yamaguchi, Kenji Nakagawa

J Clin Med Res· April 2023

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Usefulness of Serum Soluble Interleukin-2 Receptor Levels for Differentiating between PCNSL and SCNSL.
Yuta Mitobe, Ken-Ichiro Matsuda, Yukihiko Sonoda

Neurol Med Chir (Tokyo)· March 2023

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Givinostat Inhibition of Sp1-dependent MGMT Expression Sensitizes Glioma Stem Cells to Temozolomide.
Yurika Nakagawa-Saito, Yuta Mitobe, Keita Togashi, Shuhei Suzuki, Asuka Sugai

Anticancer Res· March 2023

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