Publications by authors named "Yvan Varisco"

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Extracellular PHF-tau modulates astrocyte mitochondrial dynamics and mediates neuronal connectivity.
Valentin Zufferey, Aatmika Barve, Enea Parietti, Luc Belinga, Audrey Bringaud, Yvan Varisco

Transl Neurodegener· March 2025

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Discovery of 2-(4-(2-fluoroethoxy)piperidin-1-yl)-9-methyl-9H-pyrrolo[2,3-b:4,5-c']dipyridine ([18F]PI-2014) as PET tracer for the detection of pathological aggregated tau in Alzheimer's disease and other tauopathies.
Emanuele Gabellieri, Francesca Capotosti, Jerome Molette, Nampally Sreenivasachary, Andre Mueller, Yvan Varisco

Eur J Med Chem· October 2020

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Discovery and preclinical characterization of [F]PI-2620, a next-generation tau PET tracer for the assessment of tau pathology in Alzheimer's disease and other tauopathies.
Heiko Kroth, Felix Oden, Jerome Molette, Hanno Schieferstein, Francesca Capotosti, Yvan Varisco

Eur J Nucl Med Mol Imaging· September 2019

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Discovery and characterization of novel indole and 7-azaindole derivatives as inhibitors of β-amyloid-42 aggregation for the treatment of Alzheimer's disease.
Nampally Sreenivasachary, Heiko Kroth, Pascal Benderitter, Anne Hamel, Yvan Varisco

Bioorg Med Chem Lett· March 2017

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Synthesis and structure-activity relationship of 2,6-disubstituted pyridine derivatives as inhibitors of β-amyloid-42 aggregation.
Heiko Kroth, Nampally Sreenivasachary, Anne Hamel, Pascal Benderitter, Yvan Varisco

Bioorg Med Chem Lett· July 2016

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Discovery and structure activity relationship of small molecule inhibitors of toxic β-amyloid-42 fibril formation.
Heiko Kroth, Annalisa Ansaloni, Yvan Varisco, Asad Jan, Nampally Sreenivasachary

J Biol Chem· October 2012

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An effector-reduced anti-β-amyloid (Aβ) antibody with unique aβ binding properties promotes neuroprotection and glial engulfment of Aβ.
Oskar Adolfsson, Maria Pihlgren, Nicolas Toni, Yvan Varisco, Anna Lucia Buccarello

J Neurosci· July 2012

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