Publications by authors named "Zachary D Wallen"

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Correction: RB1 expression and HR proficiency define a poor prognosis subtype of high grade serous ovarian cancer.
Kyle C Strickland, Zachary D Wallen, Heidi C Ko, Michelle F Green, Alicia Dillard

Sci Rep· October 2025

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Utilization of a Multi-modal Comprehensive Genomic and Immune Profiling Testing Strategy Results in a High Rate of Test Success and Detection of Clinically Relevant Biomarkers While Optimizing Tissue Usage.
Michelle F Green, Zachary D Wallen, Heidi C Ko, Kyle C Strickland, Alicia Dillard

Mol Diagn Ther· September 2025

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RB1 expression and HR proficiency define a poor prognosis subtype of high grade serous ovarian cancer.
Kyle C Strickland, Zachary D Wallen, Heidi C Ko, Michelle F Green, Alicia Dillard

Sci Rep· August 2025

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RNA hybrid-capture next-generation sequencing has high sensitivity in identifying known and less characterized oncogenic and likely oncogenic fusions in a real-world standard-of-care setting.
Zachary D Wallen, Marni Tierno, Erica Schnettler, Alison Roos, Michelle Green

Front Genet· May 2025

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Alpha synuclein overexpression can drive microbiome dysbiosis in mice.
Timothy R Sampson, Zachary D Wallen, Woong-Jai Won, David G Standaert, Haydeh Payami

Sci Rep· February 2025

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Genomic profiling of NSCLC tumors with the TruSight oncology 500 assay provides broad coverage of clinically actionable genomic alterations and detection of known and novel associations between genomic alterations, TMB, and PD-L1.
Zachary D Wallen, Mary K Nesline, Marni Tierno, Alison Roos, Erica Schnettler

Front Oncol· November 2024

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Biomarkers in head and neck squamous cell carcinoma: unraveling the path to precision immunotherapy.
Kamal S Saini, Sasikala Somara, Heidi C Ko, Purva Thatai, Angela Quintana, Zachary D Wallen

Front Oncol· October 2024

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Case report: Single gene testing and comprehensive genomic profiling in non-small cell lung cancer-a case series of divergent results from a large reference laboratory.
Kyle C Strickland, Mary K Nesline, Rebecca A Previs, Heidi Ko, Maureen Cooper, Zachary D Wallen

Front Oncol· October 2024

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A consensus-based classification workflow to determine genetically inferred ancestry from comprehensive genomic profiling of patients with solid tumors.
Zachary D Wallen, Mary K Nesline, Sarabjot Pabla, Shuang Gao, Erik Vanroey

Brief Bioinform· September 2024

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Real-world comprehensive genomic and immune profiling reveals distinct age- and sex-based genomic and immune landscapes in tumors of patients with non-small cell lung cancer.
Zachary D Wallen, Heidi Ko, Mary K Nesline, Stephanie B Hastings, Kyle C Strickland

Front Immunol· July 2024

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The Impact of Prior Single-Gene Testing on Comprehensive Genomic Profiling Results for Patients with Non-Small Cell Lung Cancer.
Mary K Nesline, Vivek Subbiah, Rebecca A Previs, Kyle C Strickland, Heidi Ko, Zachary D Wallen

Oncol Ther· June 2024

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Population fraction of Parkinson's disease attributable to preventable risk factors.
Haydeh Payami, Gwendolyn Cohen, Charles F Murchison, Timothy R Sampson, David G Standaert, Zachary D Wallen

NPJ Parkinsons Dis· December 2023

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Population fraction of Parkinson's disease attributable to preventable risk factors.
Haydeh Payami, Gwendolyn Cohen, Charles F Murchison, Timothy R Sampson, David G Standaert, Zachary D Wallen

medRxiv· May 2023

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Metagenomics of Parkinson's disease implicates the gut microbiome in multiple disease mechanisms.
Zachary D Wallen, Ayse Demirkan, Guy Twa, Gwendolyn Cohen, Marissa N Dean

Nat Commun· November 2022

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Oral ingestion of the environmental toxicant trichloroethylene in rats induces alterations in the gut microbiome: Relevance to idiopathic Parkinson's disease.
Neda M Ilieva, Zachary D Wallen, Briana R De Miranda

Toxicol Appl Pharmacol· September 2022

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Exploring human-genome gut-microbiome interaction in Parkinson's disease.
Zachary D Wallen, William J Stone, Stewart A Factor, Eric Molho, Cyrus P Zabetian

NPJ Parkinsons Dis· August 2021

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Comparison study of differential abundance testing methods using two large Parkinson disease gut microbiome datasets derived from 16S amplicon sequencing.
Zachary D Wallen

BMC Bioinformatics· May 2021

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Large-scale association analyses identify host factors influencing human gut microbiome composition.
Alexander Kurilshikov, Carolina Medina-Gomez, Rodrigo Bacigalupe, Djawad Radjabzadeh, Jun Wang, Zachary D Wallen

Nat Genet· February 2021

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Innate and adaptive immune responses in Parkinson's disease.
Aubrey M Schonhoff, Gregory P Williams, Zachary D Wallen, David G Standaert, Ashley S Harms

Prog Brain Res· January 2021

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Characterizing dysbiosis of gut microbiome in PD: evidence for overabundance of opportunistic pathogens.
Zachary D Wallen, Mary Appah, Marissa N Dean, Cheryl L Sesler, Stewart A Factor

NPJ Parkinsons Dis· June 2020

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Plasticity-related gene 3 () and age at diagnosis of Parkinson disease.
Zachary D Wallen, Honglei Chen, Erin M Hill-Burns, Stewart A Factor, Cyrus P Zabetian

Neurol Genet· October 2018

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Parkinson's disease and Parkinson's disease medications have distinct signatures of the gut microbiome.
Erin M Hill-Burns, Justine W Debelius, James T Morton, William T Wissemann, Matthew R Lewis, Zachary D Wallen

Mov Disord· May 2017

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