Publications by authors named "Zachary Gerhart-Hines"

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Altered brown fat thermoregulation and enhanced cold-induced thermogenesis in young, healthy, winter-swimming men.
Susanna Søberg, Johan Löfgren, Frederik E Philipsen, Michal Jensen, Adam E Hansen, Esben Ahrens, Kristin B Nystrup, Rune D Nielsen, Christine Sølling, Anne-Sophie Wedell-Neergaard

Cell Rep Med· October 2021

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Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha.
Marie Lagouge, Carmen Argmann, Zachary Gerhart-Hines, Hamid Meziane, Carles Lerin, Frederic Daussin, Nadia Messadeq, Jill Milne, Philip Lambert, Peter Elliott

December 2006

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NAD depletion in skeletal muscle does not compromise muscle function or accelerate aging.
Sabina Chubanava, Iuliia Karavaeva, Amy M Ehrlich, Roger M Justicia, Astrid L Basse, Zachary Gerhart-Hines

Cell Metab· December 2025

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Single cell transcriptomics of human weight loss links adipocyte NPY1R to control of lipolysis.
Julius E R Grothen, Jaime M Martinez, Nikos Sidiropoulos, Lucas Massier, Danae Zareifi, Zachary Gerhart-Hines

Mol Metab· December 2025

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The NMDA Receptor Antagonist Memantine Modulates Aging and Stress Resilience.
Vaida Juozaityte, Chiara Pregnolato, Steffen Abay-Nørgaard, Dylan Matthew Rausch, Rebecca L McIntyre, Zachary Gerhart-Hines

Aging Cell· November 2025

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Cold exposure induces the constitutively active thermogenic receptor, GPR3, via ERRα and ERRγ.
Olivia Sveidahl Johansen, Rebecca L McIntyre, Janane F Rahbani, Qiaoqiao Zhang, Charlotte Scholtes, Zachary Gerhart-Hines

Mol Metab· October 2025

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A consensus guide to preclinical indirect calorimetry experiments.
Alexander S Banks, David B Allison, Thierry Alquier, Ansarullah, Steven N Austad, Zachary Gerhart-Hines

Nat Metab· September 2025

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Shaping the future of cardiometabolic innovation: advances and opportunities.
Christoffer Clemmensen, Zachary Gerhart-Hines, Thue W Schwartz, Juleen R Zierath, Kei Sakamoto

Nat Metab· August 2025

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Intracrine FFA4 signaling controls lipolysis at lipid droplets.
Shannon L O'Brien, Emma Tripp, Natasja Barki, Elodie Blondel-Tepaz, Gabrielle Smith, Zachary Gerhart-Hines

Nat Chem Biol· August 2025

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Transcriptomic signatures of cold acclimated adipocytes reveal CXCL12 as a Brown autocrine and paracrine chemokine.
Marina Agueda-Oyarzabal, Marie S Isidor, Kaja Plucińska, Lars R Ingerslev, Oksana Dmytriyeva, Zachary Gerhart-Hines

Mol Metab· March 2025

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Exposing mice to extremely hypertonic treatments: a recurring problem in lactate research.
Jens Lund, Zachary Gerhart-Hines, Christoffer Clemmensen

J Physiol· January 2025

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NK2R control of energy expenditure and feeding to treat metabolic diseases.
Frederike Sass, Tao Ma, Jeppe H Ekberg, Melissa Kirigiti, Mario G Ureña, Zachary Gerhart-Hines

Nature· November 2024

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Mild Cold Stress at Ambient Temperature Elevates Muscle Calcium Cycling and Exercise Adaptations in Obese Female Mice.
Steffen H Raun, Jessica L Braun, Iuliia Karavaeva, Carlos Henriquez-Olguín, Mona S Ali, Zachary Gerhart-Hines

Endocrinology· August 2024

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MCT1 helps brown fat suck up succinate.
Jens Lund, Marie Sophie Isidor, Zachary Gerhart-Hines

Nat Metab· March 2024

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Is lactate a driver of skin burn-induced adipose browning?
Jens Lund, Valdemar Brimnes Ingemann Johansen, Christoffer Clemmensen, Zachary Gerhart-Hines

Am J Physiol Endocrinol Metab· October 2023

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Effect of Simvastatin Treatment on Mitochondrial Function and Inflammatory Status of Human White Adipose Tissue.
Ida Bager Christensen, Ida Blom, Tine Lovsø Dohlmann, Fabian Finger, Jørn W Helge, Zachary Gerhart-Hines

J Clin Endocrinol Metab· September 2023

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TNIK is a conserved regulator of glucose and lipid metabolism in obesity.
T C Phung Pham, Lucile Dollet, Mona S Ali, Steffen H Raun, Lisbeth L V Møller, Zachary Gerhart-Hines

Sci Adv· August 2023

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Full activation of thermogenesis in brown adipocytes requires Basigin action.
Kaja Rupar, Marie S Isidor, Lidia Argemi-Muntadas, Marina Agueda-Oyarzabal, Kaja Plucińska, Zachary Gerhart-Hines

FEBS J· May 2023

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NAMPT-dependent NAD biosynthesis controls circadian metabolism in a tissue-specific manner.
Astrid L Basse, Karen N Nielsen, Iuliia Karavaeva, Lars R Ingerslev, Tao Ma, Zachary Gerhart-Hines

Proc Natl Acad Sci U S A· April 2023

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The anorectic and thermogenic effects of pharmacological lactate in male mice are confounded by treatment osmolarity and co-administered counterions.
Jens Lund, Alberte Wollesen Breum, Cláudia Gil, Sarah Falk, Frederike Sass, Zachary Gerhart-Hines

Nat Metab· April 2023

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Mitochondrial phosphatidylethanolamine modulates UCP1 to promote brown adipose thermogenesis.
Jordan M Johnson, Alek D Peterlin, Enrique Balderas, Elahu G Sustarsic, J Alan Maschek, Zachary Gerhart-Hines

Sci Adv· February 2023

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Ribosome stalling is a signal for metabolic regulation by the ribotoxic stress response.
Goda Snieckute, Aitana Victoria Genzor, Anna Constance Vind, Laura Ryder, Mark Stoneley, Zachary Gerhart-Hines

Cell Metab· December 2022

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ADRA1A-Gα signalling potentiates adipocyte thermogenesis through CKB and TNAP.
Janane F Rahbani, Charlotte Scholtes, Damien M Lagarde, Mohammed F Hussain, Anna Roesler, Zachary Gerhart-Hines

Nat Metab· November 2022

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Lipolysis regulates major transcriptional programs in brown adipocytes.
Lasse K Markussen, Elizabeth A Rondini, Olivia Sveidahl Johansen, Jesper G S Madsen, Elahu G Sustarsic, Zachary Gerhart-Hines

Nat Commun· July 2022

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Leveraging GPCR signaling in thermogenic fat to counteract metabolic diseases.
Olivia Sveidahl Johansen, Tao Ma, Zachary Gerhart-Hines

Mol Metab· June 2022

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Fueling the fire of adipose thermogenesis.
Christian Wolfrum, Zachary Gerhart-Hines

Science· March 2022

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