Publications by authors named "Zdravko Varagic"

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Engineered Flumazenil Recognition Site Provides Mechanistic Insight Governing Benzodiazepine Modulation in GABA Receptors.
David C B Siebert, Konstantina Bampali, Roshan Puthenkalam, Zdravko Varagic, Isabella Sarto-Jackson

ACS Chem Biol· August 2018

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Towards functional selectivity for α6β3γ2 GABA receptors: a series of novel pyrazoloquinolinones.
Marco Treven, David C B Siebert, Raphael Holzinger, Konstantina Bampali, Jure Fabjan, Zdravko Varagic

Br J Pharmacol· February 2018

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Molecular tools for GABA receptors: High affinity ligands for β1-containing subtypes.
Xenia Simeone, David C B Siebert, Konstantina Bampali, Zdravko Varagic, Marco Treven

Sci Rep· July 2017

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Targeting the γ-Aminobutyric Acid A Receptor α4 Subunit in Airway Smooth Muscle to Alleviate Bronchoconstriction.
Gene T Yocum, George Gallos, Yi Zhang, Rajwana Jahan, Michael Rajesh Stephen, Zdravko Varagic

Am J Respir Cell Mol Biol· April 2016

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Unexpected Properties of δ-Containing GABAA Receptors in Response to Ligands Interacting with the α+ β- Site.
Pantea Mirheydari, Joachim Ramerstorfer, Zdravko Varagic, Petra Scholze, Laurin Wimmer

Neurochem Res· June 2014

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Sh-I-048A, an in vitro non-selective super-agonist at the benzodiazepine site of GABAA receptors: the approximated activation of receptor subtypes may explain behavioral effects.
Aleksandar Lj Obradović, Srđan Joksimović, Michael M Poe, Joachim Ramerstorfer, Zdravko Varagic

Brain Res· March 2014

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Insights into functional pharmacology of α₁ GABA(A) receptors: how much does partial activation at the benzodiazepine site matter?
Srđan Joksimović, Zdravko Varagic, Jovana Kovačević, Michael Van Linn, Marija Milić

Psychopharmacology (Berl)· November 2013

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Benzodiazepine-induced spatial learning deficits in rats are regulated by the degree of modulation of α1 GABA(A) receptors.
Srđan Joksimović, Jovana Divljaković, Michael L Van Linn, Zdravko Varagic, Gordana Brajković

Eur Neuropsychopharmacol· May 2013

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Identification of novel positive allosteric modulators and null modulators at the GABAA receptor α+β- interface.
Zdravko Varagic, Laurin Wimmer, Michael Schnürch, Marko D Mihovilovic, Shengming Huang

Br J Pharmacol· May 2013

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Subtype selectivity of α+β- site ligands of GABAA receptors: identification of the first highly specific positive modulators at α6β2/3γ2 receptors.
Zdravko Varagic, Joachim Ramerstorfer, Shengming Huang, Sundari Rallapalli, Isabella Sarto-Jackson

Br J Pharmacol· May 2013

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Search for α3β₂/₃γ2 subtype selective ligands that are stable on human liver microsomes.
Ojas A Namjoshi, Zhi-jian Wang, Sundari K Rallapalli, Edward Merle Johnson, Yun-Teng Johnson, Zdravko Varagic

Bioorg Med Chem· January 2013

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A novel GABA(A) receptor pharmacology: drugs interacting with the α(+) β(-) interface.
Werner Sieghart, Joachim Ramerstorfer, Isabella Sarto-Jackson, Zdravko Varagic, Margot Ernst

Br J Pharmacol· May 2012

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Diazepam-bound GABAA receptor models identify new benzodiazepine binding-site ligands.
Lars Richter, Chris de Graaf, Werner Sieghart, Zdravko Varagic, Martina Mörzinger

Nat Chem Biol· March 2012

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The GABAA receptor alpha+beta- interface: a novel target for subtype selective drugs.
Joachim Ramerstorfer, Roman Furtmüller, Isabella Sarto-Jackson, Zdravko Varagic, Werner Sieghart

J Neurosci· January 2011

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