Publications by authors named "Zeng Hu"

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Integrative multi-omic profiling in blood reveals distinct immune and metabolic signatures between ACPA-negative and ACPA-positive rheumatoid arthritis.
Benjamin Hur, Vinod K Gupta, Minsik Oh, Hu Zeng, Cynthia S Crowson

Front Immunol· November 2025

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Systems analysis uncovers early temozolomide responses and peptide antigens in glioblastoma.
Elizabeth Y Choe, Owen Leddy, Cecile Riviere-Cazaux, Danielle M Burgenske, Zeng Hu, Sabrina Hu

bioRxiv· November 2025

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The novel brain penetrant ataxia-telangiectasia mutated inhibitor WSD0628 provides robust radiosensitization of brain tumor patient-derived xenografts.
Zhiyi Xue, Ann C Mladek, Sneha Rathi, Sonia Jain, Rachael A Vaubel, Zeng Hu

Neuro Oncol· October 2025

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Gut microbiota and metabolite changes in metastatic colorectal cancer 16S rRNA and metabolomics.
Pan Deng, Hua Lin, Hu Zeng, Feng Guo

World J Gastrointest Oncol· October 2025

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Inflammatory arthritis immune related adverse events represent a unique autoimmune disease entity primarily driven by T cells, but likely not autoantibodies.
Xingxing Zhu, Yue Yu, Yanfeng Li, Panwen Wang, Ying Li, Hu Zeng

medRxiv· September 2025

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Preclinical Modeling of Navtemadlin Pharmacokinetics, Pharmacodynamics, and Efficacy in IDH-Wild-type Glioblastoma.
Rachael A Vaubel, Wenjuan Zhang, Ju-Hee Oh, Ann C Mladek, Tugce I Pasa, Zeng Hu

Clin Cancer Res· September 2025

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Spatially resolved in situ profiling of mRNA life cycle at transcriptome scale in intact cells and tissues using STARmap PLUS, RIBOmap and TEMPOmap.
Jingyi Ren, Hu Zeng, Jiahao Huang, Jiakun Tian, Morgan Wu, Shuchen Luo

Nat Protoc· September 2025

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BRD4 silencing attenuates hemin-induced neuronal ferroptosis and inflammation via the H3K27ac-ATF3 axis in an in vitro model of cerebral hemorrhage.
Jing Yi, Hua Tang, Siwei Que, Tao Zheng, Hu Zeng, Hua Chen

Eur J Med Res· July 2025

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Phosphorylation of USP33 by CDK1 stabilizes the mTORC2 component SIN1.
Yalei Wen, Caishi Zhang, Mingchao Liang, Xiao Yang, Hu Zeng, Lei Huang

Cell Death Dis· July 2025

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DNA-PK Inhibition Shows Differential Radiosensitization in Orthotopic GBM PDX Models Based on DDR Pathway Deficits.
Sonja Dragojevic, Emily J Smith, Michael S Regan, Sylwia A Stopka, Gerard Baquer, Zeng Hu, Shulan Tian

Mol Cancer Ther· June 2025

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Targeting mechanistic target of rapamycin complex 2 attenuates immunopathology in systemic lupus erythematosus.
Minji Ai, Xian Zhou, Michele Carrer, Paymaan Jafar-Nejad, Yanfeng Li, Hu Zeng

Rheumatology (Oxford)· June 2025

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Immunopipe: a comprehensive and flexible scRNA-seq and scTCR-seq data analysis pipeline.
Panwen Wang, Yue Yu, Haidong Dong, Shuwen Zhang, Zhifu Sun, Hu Zeng

NAR Genom Bioinform· June 2025

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Advances in Spatial Omics Technologies.
Tianxiao Hui, Jian Zhou, Muchen Yao, Yige Xie, Hu Zeng

Small Methods· May 2025

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Single-cell 5-hydroxymethylcytosine landscapes of mouse early embryos at single-base resolution.
Dongsheng Bai, Jinmin Yang, Xiaohui Xue, Yun Gao, Yan Wang, Hu Zeng, Huifen Xiang, Lan Zhu, Chenxu Zhu

Cell Rep· April 2025

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Chronic intermittent hypoxia modulates energy metabolic pathways and improves hypoxia tolerance capacity in golden pompano, Trachinotus blochii.
Geng Hui Fang, Xiao Li Zhou, Chun Li Ran, Chun Xiu Jin, Shao Yang Bu, Zeng Tan Hu

Sci Total Environ· March 2025

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Modeling the Acute Mucosal Toxicity of Fractionated Radiotherapy Combined with the ATM Inhibitor WSD0628.
Darwin A Garcia, Sneha Rathi, Margaret A Connors, Michael Grams, Rachael A Vaubel, Zeng Hu, Joshua D Trzasko

Mol Cancer Ther· February 2025

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The nutrient-sensing Rag-GTPase complex in B cells controls humoral immunity via TFEB/TFE3-dependent mitochondrial fitness.
Xingxing Zhu, Yue Wu, Yanfeng Li, Xian Zhou, Jens O Watzlawik, Hu Zeng

Nat Commun· November 2024

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PP2A catalytic subunit alpha is critically required for CD8 T-cell homeostasis and antibacterial responses.
Xian Zhou, Meilu Li, Minji Ai, Yanfeng Li, Xingxing Zhu, Hu Zeng

Eur J Immunol· October 2024

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CPT2-mediated Fatty Acid Oxidation Is Dispensable for Humoral Immunity.
Meilu Li, Xian Zhou, Yanfeng Li, Xingxing Zhu, Yuzhen Li, Hu Zeng

J Immunol· October 2024

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Factors Influencing the Central Nervous System (CNS) Distribution of the Ataxia Telangiectasia Mutated and Rad3-Related Inhibitor Elimusertib (BAY1895344): Implications for the Treatment of CNS Tumors.
Sneha Rathi, Ann C Mladek, Ju-Hee Oh, Sonja Dragojevic, Danielle M Burgenske, Zeng Hu

J Pharmacol Exp Ther· October 2024

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Search and match across spatial omics samples at single-cell resolution.
Zefang Tang, Shuchen Luo, Hu Zeng, Jiahao Huang, Xin Sui

Nat Methods· October 2024

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PI3K-dependent reprogramming of hexokinase isoforms controls glucose metabolism and functional responses of B lymphocytes.
Brandon T Paradoski, Sen Hou, Edgard M Mejia, Folayemi Olayinka-Adefemi, Danielle Fowke, Hu Zeng

iScience· October 2024

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Targeting mechanistic target of rapamycin complex 2 attenuates immunopathology in Systemic Lupus Erythematosus.
Minji Ai, Xian Zhou, Michele Carrer, Paymaan Jafar-Nejad, Yanfeng Li, Hu Zeng

bioRxiv· August 2024

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Immunoglobulin class-switch recombination: Mechanism, regulation, and related diseases.
Jia-Chen Liu, Ke Zhang, Xu Zhang, Fei Guan, Hu Zeng, Jia-Hui Lei, Huamei Forsman

MedComm (2020)· August 2024

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Comparative study of the clinical value of digital subtraction angiography via femoral and radial arterial paths.
Hu Zeng, Jia-Yu Xie, Li-Xin Xu, Wu-Yang Cao, Meng-Jiao Liu

Am J Transl Res· July 2024

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