Publications by authors named "Zhi-Hu Lin"

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Ganoderma microsporum-derived fungal immunomodulatory protein (GMI) promotes functional recovery after spinal cord injury by modulating anti-inflammation and enhancing regeneration.
Tsung-Hsi Tu, Ching-Jung Chen, Li-Yu Fay, Zhi-Hu Lin, Wang-Yu Hsu, Tung-Yi Lin

Exp Neurol· February 2026

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Suppression of tumor growth by GMI, an edible fungal immunomodulatory protein, is associated with targeting GSK3β‑mediated proteasomal degradation of PD‑L1.
Wei-Jyun Hua, Li-Chen Huang, Zhi-Hu Lin, Yi-Ru Ciou, Kai-Fan Lin, Tung-Yi Lin

Int J Mol Med· December 2025

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PM2.5 exposure induces transcriptomic changes in ARPE-19 cells with activation of TGFβ-mediated signaling pathways: A next-generation sequencing approach.
Chueh-Tan Chen, Zhi-Hu Lin, Tung-Yi Lin, Yi-An Lin, Hsin Yeh

J Chin Med Assoc· November 2025

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Jing Guan Fang, an herbal formula, as an immunomodulator: opposing effects on basal and lipopolysaccharide-induced inflammation of macrophage via JAK/STAT3 and MAPK pathways.
Zhi-Hu Lin, Hsin Yeh, Sang-Nguyen-Cao Phan, Li-Lan Liao, Chien-Chang Chen, Tung-Yi Lin

Front Pharmacol· September 2025

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Anti-inflammatory and anticancer effects of polysaccharides from Antrodia cinnamomea : A review.
Zhi-Hu Lin, Sang-Nguyen-Cao Phan, Diem-Ngoc-Hong Tran, Mei-Kuang Lu, Tung-Yi Lin

J Chin Med Assoc· January 2025

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Sulfated polysaccharide from Antrodia cinnamomea mycelium cultured with zinc sulfate stimulates M1 polarization of macrophages through AKT/mTOR pathways.
Zhi-Hu Lin, Hung-Chih Lo, Chia-Chuan Chang, Mei-Kuang Lu, Ai-Jung Tseng, Tung-Yi Lin

Int J Biol Macromol· November 2024

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Quality and production enhancement of fish mint, Thunb., cultivated in a hydroponic planting system with designed plant growth-promoting additives.
Yen Chi Loo, Yi-Hong Tsai, Hsieh Chen, Hui-Ping Hsieh, Yen-Chang Chen, Zhi-Hu Lin

Heliyon· April 2024

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Ganoderma microsporum immunomodulatory protein combined with KRAS inhibitor impedes intracellular AKT/ERK network to suppress lung cancer cells with KRAS mutation.
Wei-Jyun Hua, Wei-Lun Hwang, Hsin Yeh, Zhi-Hu Lin, Wei-Hung Hsu, Tung-Yi Lin

Int J Biol Macromol· February 2024

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Exosomal circHIPK3 derived from umbilical cord-derived mesenchymal stem cells enhances skin fibroblast autophagy by blocking miR-20b-5p/ULK1/Atg13 axis.
Zhi-Yang Qiu, Shi-Shuai Lin, Nan-Fang Pan, Zhi-Hu Lin, Yun-Chuan Pan

J Diabetes Investig· December 2023

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Ganoderma microsporum immunomodulatory protein as an extracellular epidermal growth factor receptor (EGFR) degrader for suppressing EGFR-positive lung cancer cells.
Wei-Jyun Hua, Hsin Yeh, Zhi-Hu Lin, Ai-Jung Tseng, Li-Chen Huang, Tung-Yi Lin

Cancer Lett· December 2023

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GMI, a Ganoderma microsporum protein, abolishes focal adhesion network to reduce cell migration and metastasis of lung cancer.
Hung-Chih Lo, Wei-Jyun Hua, Hsin Yeh, Zhi-Hu Lin, Li-Chen Huang, Kai-Fan Lin, Tung-Yi Lin

Life Sci· December 2023

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Corrigendum to "ZnF3, a sulfated polysaccharide from Antrodia cinnamomea, inhibits lung cancer cells via induction of apoptosis and activation of M1-like macrophage-induced cell death" [Int. J. Biol. Macromol. 238 (2023) 124144].
Zhi-Hu Lin, Mei-Kuang Lu, Hung-Chih Lo, Chia-Chuan Chang, Ai-Jung Tseng, Tung-Yi Lin

Int J Biol Macromol· October 2023

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Corrigendum: The traditional Chinese medicine formula Jing Guan Fang for preventing SARS-CoV-2 infection: from clinical observation to basic research.
Yueh-Hsin Ping, Hsin Yeh, Li-Wei Chu, Zhi-Hu Lin, Yin-Chieh Hsu, Lie-Chwen Lin, Shu-Ling Fu, Tung-Yi Lin

Front Pharmacol· August 2023

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New -kaurene and germacrene derivatives from Hemseley and their biological activity.
Jerome G Ganzon, Chia-Ching Liaw, Yu-Chi Lin, Zhi-Hu Lin, Chang-Hung Wang

Nat Prod Res· July 2023

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GMI, a fungal immunomodulatory protein, ameliorates SARS-CoV-2 envelope protein-induced inflammation in macrophages via inhibition of MAPK pathway.
Zhi-Hu Lin, Hsin Yeh, Hung-Chih Lo, Wei-Jyun Hua, Ming-Yang Ni, Tung-Yi Lin

Int J Biol Macromol· June 2023

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ZnF3, a sulfated polysaccharide from Antrodia cinnamomea, inhibits lung cancer cells via induction of apoptosis and activation of M1-like macrophage-induced cell death.
Zhi-Hu Lin, Mei-Kuang Lu, Hung-Chih Lo, Chia-Chuan Chang, Ai-Jung Tseng, Tung-Yi Lin

Int J Biol Macromol· May 2023

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UCMSCs-derived exosomal circHIPK3 promotes ulcer wound angiogenesis of diabetes mellitus via miR-20b-5p/Nrf2/VEGFA axis.
Zun-Hong Liang, Shi-Shuai Lin, Nan-Fang Pan, Guo-Yu Zhong, Zhi-Yang Qiu, Zhi-Hu Lin

Diabet Med· February 2023

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GMI, Ganoderma microsporum protein, suppresses cell mobility and increases temozolomide sensitivity through induction of Slug degradation in glioblastoma multiforme cells.
Ai-Jung Tseng, Tsung-Hsi Tu, Wei-Jyun Hua, Hsin Yeh, Ching-Jung Chen, Zhi-Hu Lin, Tung-Yi Lin

Int J Biol Macromol· October 2022

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GMI, a protein from Ganoderma microsporum, induces ACE2 degradation to alleviate infection of SARS-CoV-2 Spike-pseudotyped virus.
Hsin Yeh, Di Ngoc Kha Vo, Zhi-Hu Lin, Ha Phan Thanh Ho, Wei-Jyun Hua, Tung-Yi Lin

Phytomedicine· August 2022

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Neritriterpenols A-G, euphane and tirucallane triterpenes from Euphorbia neriifolia L. and their bioactivity.
Stephen S Chang, Hung-Tse Huang, Yu-Chi Lin, Chih-Hua Chao, Geng-You Liao, Zhi-Hu Lin, Jenny Chun-Ling Kuo

Phytochemistry· July 2022

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Anti-inflammatory constituents from Hayata.
Chia-Ching Liaw, Yu-Chi Lin, Shao-Yu Wu, Jenny Chun-Ling Kuo, Zhi-Hu Lin, Kai-Wei Lin

Nat Prod Res· March 2022

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The Traditional Chinese Medicine Formula Jing Guan Fang for Preventing SARS-CoV-2 Infection: From Clinical Observation to Basic Research.
Yueh-Hsin Ping, Hsin Yeh, Li-Wei Chu, Zhi-Hu Lin, Yin-Chieh Hsu, Lie-Chwen Lin, Shu-Ling Fu, Tung-Yi Lin

Front Pharmacol· March 2022

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Water extract of medicinal ink (WEMI) attenuates lipopolysaccharide-induced NO production of Raw264.7 cells via downregulating JAK2/STAT3-mediated iNOS expression.
Zhi-Hu Lin, Jinsong Hu, Huagang Shi, Chia-Ching Liaw, Wei-Lun Qiu, Tung-Yi Lin

J Ethnopharmacol· January 2022

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WSG, a Glucose-Rich Polysaccharide from , Combined with Cisplatin Potentiates Inhibition of Lung Cancer and .
Wei-Lun Qiu, Wei-Hung Hsu, Shu-Ming Tsao, Ai-Jung Tseng, Zhi-Hu Lin, Tzu-En Lin, Tung-Yi Lin

Polymers (Basel)· December 2021

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Synthesis, biological evaluation, and correlation of cytotoxicity versus redox potential of 1,4-naphthoquinone derivatives.
Chien-Chang Shen, Shakil N Afraj, Chia-Cheng Hung, Balaji D Barve, Li-Ming Yang Kuo, Zhi-Hu Lin

Bioorg Med Chem Lett· June 2021

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