Publications by authors named "Zhonghui Lin"

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Association between the platelet-albumin-bilirubin score and all-cause mortality in ICU-admitted heart failure patients: a retrospective cohort analysis and machine learning-based prognostic modeling.
Zhantao Cao, Jian Li, Guanfa Yuan, Jinghua Ren, Jingting Chen, Kailin Zheng, Zhonghui Lin

Front Cardiovasc Med· November 2025

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Punicalagin as an Artemis inhibitor synergizes with photodynamic therapy in tumor suppression.
Xuening Chen, Changkun Chen, Zuoan Li, Chun Liu, Zhonghui Lin

Bioorg Chem· April 2025

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A gate-clamp mechanism for ssDNA translocation by DdmD in Vibrio cholerae plasmid defense.
Ruoyu Li, Yusong Liu, Haishan Gao, Zhonghui Lin

Nucleic Acids Res· January 2025

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Discovery of KPT-6566 as STAG1/2 Inhibitor sensitizing PARP and NHEJ Inhibitors to suppress tumor cells growth in vitro.
Qinwei Zhu, Xuening Chen, Zhonghui Lin

DNA Repair (Amst)· December 2024

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Walrycin B, as a novel separase inhibitor, exerts potent anticancer efficacy in a mouse xenograft model.
Qinwei Zhu, Liyang Du, Juhong Wu, Jinyu Li, Zhonghui Lin

Biochem Pharmacol· November 2024

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Structural insight into the Csx1-Crn2 fusion self-limiting ribonuclease of type III CRISPR system.
Danping Zhang, Liyang Du, Haishan Gao, Cai Yuan, Zhonghui Lin

Nucleic Acids Res· August 2024

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Discovery of UMI-77 as a novel Ku70/80 inhibitor sensitizing cancer cells to DNA damaging agents in vitro and in vivo.
Xuening Chen, Changkun Chen, Chengmiao Luo, Jianyong Liu, Zhonghui Lin

Eur J Pharmacol· July 2024

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Gut microbiota and sleep: Interaction mechanisms and therapeutic prospects.
Zhonghui Lin, Tao Jiang, Miaoling Chen, Xudong Ji, Yunsu Wang

Open Life Sci· July 2024

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MOC1 cleaves Holliday junctions through a cooperative nick and counter-nick mechanism mediated by metal ions.
Danping Zhang, Shenjie Xu, Zhipu Luo, Zhonghui Lin

Nat Commun· June 2024

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Ebselen and TPI-1, as RecG helicase inhibitors, potently enhance the susceptibility of Pseudomonas aeruginosa to DNA damage agents.
Longheng Li, Binbin Guo, Lin Dai, Chun Liu, Zhonghui Lin

Biochem Pharmacol· April 2024

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Molecular mechanism of allosteric activation of the CRISPR ribonuclease Csm6 by cyclic tetra-adenylate.
Liyang Du, Qinwei Zhu, Zhonghui Lin

EMBO J· January 2024

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Identification of small-molecule inhibitors of human MUS81-EME1/2 by FRET-based high-throughput screening.
Xu Zhang, Xuening Chen, Lian Lu, Qianqian Fang, Chun Liu, Zhonghui Lin

Bioorg Med Chem· July 2023

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Quantification of Isoniazid-Heteroresistant Mycobacterium tuberculosis Using Droplet Digital PCR.
Siqi Zhang, Xiaohong Chen, Zhonghui Lin, Yaoju Tan, Bin Liang

J Clin Microbiol· June 2023

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Molecular basis of stepwise cyclic tetra-adenylate cleavage by the type III CRISPR ring nuclease Crn1/Sso2081.
Liyang Du, Danping Zhang, Zhipu Luo, Zhonghui Lin

Nucleic Acids Res· March 2023

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Cryo-EM structure of the RuvAB-Holliday junction intermediate complex from .
Xu Zhang, Zixuan Zhou, Lin Dai, Yulin Chao, Zheng Liu, Zhonghui Lin

Front Plant Sci· March 2023

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Discovery of a novel Aurora B inhibitor GSK650394 with potent anticancer and anti- dual efficacies .
Yuhua He, Wei Fu, Liyang Du, Huiqiao Yao, Zhengkang Hua, Zhonghui Lin

J Enzyme Inhib Med Chem· December 2022

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A promising strategy for synergistic cancer therapy by integrating a photosensitizer into a hypoxia-activated prodrug.
De-Chao Yang, Xiao-Zhen Yang, Cheng-Miao Luo, Lin-Feng Wen, Jian-Yong Liu, Zhonghui Lin

Eur J Med Chem· December 2022

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Identification of small-molecule inhibitors of the DNA repair proteins RuvAB from Pseudomonas aeruginosa.
Lin Dai, Lian Lu, Xu Zhang, Juhong Wu, Jinyu Li, Zhonghui Lin

Bioorg Med Chem· November 2022

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Punicalagin as an allosteric NSP13 helicase inhibitor potently suppresses SARS-CoV-2 replication in vitro.
Lian Lu, Yun Peng, Huiqiao Yao, Yanqun Wang, Jinyu Li, Zhonghui Lin

Antiviral Res· October 2022

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A protocol to determine the activities of human MUS81-EME1&2 endonucleases.
Qianqian Fang, Zhengkang Hua, Zhonghui Lin

STAR Protoc· September 2022

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A Hypoxia-Activated Prodrug Conjugated with a BODIPY-Based Photothermal Agent for Imaging-Guided Chemo-Photothermal Combination Therapy.
De-Chao Yang, Lin-Feng Wen, Liyang Du, Cheng-Miao Luo, Zi-Yao Lu, Zhonghui Lin

ACS Appl Mater Interfaces· September 2022

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Crystal structure of the human MUS81-EME2 complex.
Zhengkang Hua, Qianqian Fang, Danping Zhang, Zhipu Luo, Cai Yuan, Zhonghui Lin

Structure· May 2022

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Singlet Oxygen-Responsive Polymeric Nanomedicine for Light-Controlled Drug Release and Image-Guided Photodynamic-Chemo Combination Therapy.
De-Chao Yang, Shuai Wang, Xiao-Lu Weng, Hong-Xia Zhang, Jian-Yong Liu, Zhonghui Lin

ACS Appl Mater Interfaces· July 2021

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Variations of forage yield and forage-livestock balance in grasslands over the Tibetan Pla-teau, China.
Xing-Guo Mo, Wen Liu, Cheng-Cheng Meng, Shi Hu, Su-Xia Liu, Zhong-Hui Lin

Ying Yong Sheng Tai Xue Bao· July 2021

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Biochemical and structural characterization of the Holliday junction resolvase RuvC from Pseudomonas aeruginosa.
Yi Hu, Yuhua He, Zhonghui Lin

Biochem Biophys Res Commun· April 2020

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