Publications by authors named "Zhuangzhuang Geng"

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Highly discriminative globin gene activation by the non-canonical BAF chromatin remodeling complex.
Abhirup Bagchi, Sindhu Billakanti, Vanessa Shehu, Kathryn M Farrell, Sarah A Cotteta, Zhuangzhuang Geng

Blood· November 2025

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Germline pathogenic variation impacts somatic alterations and patient outcomes in pediatric central nervous system tumors.
Ryan J Corbett, Rebecca S Kaufman, Shelly W McQuaid, Zalman Vaksman, Saksham Phul, Zhuangzhuang Geng

Nat Commun· November 2025

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Characterization of aberrant splicing in pediatric central nervous system tumors reveals as a candidate oncogenic dependency.
Ammar S Naqvi, Patricia J Sullivan, Ryan J Corbett, Priyanka Sehgal, Karina L Conkrite, Zhuangzhuang Geng

bioRxiv· August 2025

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Germline pathogenic variation impacts somatic alterations and patient outcomes in pediatric CNS tumors.
Ryan J Corbett, Rebecca S Kaufman, Shelly W McQuaid, Zalman Vaksman, Saksham Phul, Zhuangzhuang Geng

medRxiv· July 2025

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The Open Pediatric Cancer Project.
Zhuangzhuang Geng, Eric Wafula, Ryan J Corbett, Yuanchao Zhang, Run Jin

bioRxiv· June 2025

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Genetic ancestry superpopulations show distinct prevalence and outcomes across pediatric central nervous system tumors from the Pediatric Brain Tumor Atlas and Pediatric Neuro-Oncology Consortium.
Ryan J Corbett, Cricket C Gullickson, Zhuangzhuang Geng, Miguel A Brown, Bo Zhang

Neuro Oncol· June 2025

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The zinc-finger protein POGZ associates with Polycomb repressive complex 1 to regulate bone morphogenetic protein signaling during neuronal differentiation.
Jessenia Chavez, Trevor Wolf, Zhuangzhuang Geng, Yen Teng Tai, Kathleen Bright

bioRxiv· January 2025

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The Open Pediatric Cancer Project.
Zhuangzhuang Geng, Eric Wafula, Ryan J Corbett, Yuanchao Zhang, Run Jin

Gigascience· January 2025

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PRC1 and CTCF-Mediated Transition from Poised to Active Chromatin Loops Drives Bivalent Gene Activation.
Aflah Hanafiah, Zhuangzhuang Geng, Tingting Liu, Yen Teng Tai, Wenjie Cai

bioRxiv· November 2024

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AUTS2 disruption causes neuronal differentiation defects in human cerebral organoids through hyperactivation of the WNT/β-catenin pathway.
Zhuangzhuang Geng, Yen Teng Tai, Qiang Wang, Zhonghua Gao

Sci Rep· August 2024

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AutoGVP: a dockerized workflow integrating ClinVar and InterVar germline sequence variant classification.
Jung Kim, Ammar S Naqvi, Ryan J Corbett, Rebecca S Kaufman, Zalman Vaksman, Zhuangzhuang Geng

Bioinformatics· March 2024

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AutoGVP: a dockerized workflow integrating ClinVar and InterVar germline sequence variant classification.
Jung Kim, Ammar S Naqvi, Ryan J Corbett, Rebecca S Kaufman, Zalman Vaksman, Zhuangzhuang Geng

bioRxiv· December 2023

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AUTS2 Controls Neuronal Lineage Choice Through a Novel PRC1-Independent Complex and BMP Inhibition.
Zhuangzhuang Geng, Qiang Wang, Weili Miao, Trevor Wolf, Jessenia Chavez

Stem Cell Rev Rep· February 2023

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Mammalian PRC1 Complexes: Compositional Complexity and Diverse Molecular Mechanisms.
Zhuangzhuang Geng, Zhonghua Gao

Int J Mol Sci· November 2020

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Author Correction: Mutant p53 drives clonal hematopoiesis through modulating epigenetic pathway.
Sisi Chen, Qiang Wang, Hao Yu, Maegan L Capitano, Sasidhar Vemula, Zhuangzhuang Geng

Nat Commun· July 2020

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Differentiation and Characterization of Neural Progenitors and Neurons from Mouse Embryonic Stem Cells.
Aflah Hanafiah, Zhuangzhuang Geng, Qiang Wang, Zhonghua Gao

J Vis Exp· May 2020

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Mutant p53 drives clonal hematopoiesis through modulating epigenetic pathway.
Sisi Chen, Qiang Wang, Hao Yu, Maegan L Capitano, Sasidhar Vemula, Zhuangzhuang Geng

Nat Commun· December 2019

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WDR68 is essential for the transcriptional activation of the PRC1-AUTS2 complex and neuronal differentiation of mouse embryonic stem cells.
Qiang Wang, Zhuangzhuang Geng, Yi Gong, Kaitlyn Warren, Haiyan Zheng

Stem Cell Res· December 2018

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