Publications by authors named "Zu-Lin Chen"

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Association between cardiopulmonary exercise capacity and clinical parameters in post-PCI patients with coronary artery disease from Fujian, China.
LiHan Lin, Delong Li, YiPing Liu, GuoPeng Hu, Wei Zheng, ZuLin Chen

Front Cardiovasc Med· October 2025

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Lecanemab blocks the effects of the Aβ/fibrinogen complex on blood clots and synapse toxicity in organotypic culture.
Pradeep Kumar Singh, Elisa Nicoloso Simões-Pires, Zu-Lin Chen, Daniel Torrente, Marissa Calvano

Proc Natl Acad Sci U S A· April 2024

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Lecanemab Blocks the Effects of the Aβ/Fibrinogen Complex on Blood Clots and Synapse Toxicity in Organotypic Culture.
Pradeep Kumar Singh, Elisa Nicoloso Simoes Pires, Zu-Lin Chen, Daniel Torrente, Marissa Calvano

bioRxiv· January 2024

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A possible mechanism for the enhanced toxicity of beta-amyloid protofibrils in Alzheimer's disease.
Zu-Lin Chen, Pradeep K Singh, Marissa Calvano, Erin H Norris, Sidney Strickland

Proc Natl Acad Sci U S A· September 2023

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Anti-HK antibody inhibits the plasma contact system by blocking prekallikrein and factor XI activation in vivo.
Zu-Lin Chen, Pradeep K Singh, Katharina Horn, Marissa R Calvano, Shigeru Kaneki

Blood Adv· April 2023

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Striatal fibrinogen extravasation and vascular degeneration correlate with motor dysfunction in an aging mouse model of Alzheimer's disease.
Hanna E Berk-Rauch, Arnab Choudhury, Allison T Richards, Pradeep K Singh, Zu-Lin Chen

Front Aging Neurosci· March 2023

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Blocking domain 6 of high molecular weight kininogen to understand intrinsic clotting mechanisms.
Pradeep K Singh, Zu-Lin Chen, Katharina Horn, Erin H Norris

Res Pract Thromb Haemost· October 2022

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Anti-HK antibody reveals critical roles of a 20-residue HK region for Aβ-induced plasma contact system activation.
Zu-Lin Chen, Pradeep Kumar Singh, Katharina Horn, Sidney Strickland, Erin H Norris

Blood Adv· May 2022

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Increased Contact System Activation in Mild Cognitive Impairment Patients with Impaired Short-Term Memory.
Pradeep K Singh, Zu-Lin Chen, Sidney Strickland, Erin H Norris

J Alzheimers Dis· September 2021

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Plasmin-mediated cleavage of high-molecular-weight kininogen contributes to acetaminophen-induced acute liver failure.
Michael W Henderson, Erica M Sparkenbaugh, Shaobin Wang, Anton Ilich, Denis F Noubouossie, Zu-Lin Chen

Blood· July 2021

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The contact activation system and vascular factors as alternative targets for Alzheimer's disease therapy.
Pradeep K Singh, Ana Badimon, Zu-Lin Chen, Sidney Strickland, Erin H Norris

Res Pract Thromb Haemost· May 2021

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Increased plasma bradykinin level is associated with cognitive impairment in Alzheimer's patients.
Pradeep K Singh, Zu-Lin Chen, Dhiman Ghosh, Sidney Strickland, Erin H Norris

Neurobiol Dis· June 2020

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An antibody against HK blocks Alzheimer's disease peptide β-amyloid-induced bradykinin release in human plasma.
Zu-Lin Chen, Pradeep Singh, Jyen Wong, Katharina Horn, Sidney Strickland

Proc Natl Acad Sci U S A· November 2019

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Plasminogen mediates communication between the peripheral and central immune systems during systemic immune challenge with lipopolysaccharide.
Sarah K Baker, Zu-Lin Chen, Erin H Norris, Sidney Strickland

J Neuroinflammation· August 2019

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Blood-derived plasminogen drives brain inflammation and plaque deposition in a mouse model of Alzheimer's disease.
Sarah K Baker, Zu-Lin Chen, Erin H Norris, Alexey S Revenko, A Robert MacLeod

Proc Natl Acad Sci U S A· October 2018

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A novel detection method of cleaved plasma high-molecular-weight kininogen reveals its correlation with Alzheimer's pathology and cognitive impairment.
Hitomi Yamamoto-Imoto, Daria Zamolodchikov, Zu-Lin Chen, S Lloyd Bourne, Syeda Rizvi

Alzheimers Dement (Amst)· August 2018

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Abnormal clotting of the intrinsic/contact pathway in Alzheimer disease patients is related to cognitive ability.
Georgette L Suidan, Pradeep K Singh, Sunita Patel-Hett, Zu-Lin Chen, Dmitri Volfson

Blood Adv· May 2018

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Interactions of β-amyloid peptide with fibrinogen and coagulation factor XII may contribute to Alzheimer's disease.
Hyung J Ahn, Zu-Lin Chen, Daria Zamolodchikov, Erin H Norris, Sidney Strickland

Curr Opin Hematol· September 2017

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Depletion of coagulation factor XII ameliorates brain pathology and cognitive impairment in Alzheimer disease mice.
Zu-Lin Chen, Alexey S Revenko, Pradeep Singh, A Robert MacLeod, Erin H Norris

Blood· May 2017

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Deletion of the epidermis derived laminin γ1 chain leads to defects in the regulation of late hair morphogenesis.
Anja Fleger-Weckmann, Yasemin Üstün, Jennifer Kloepper, Ralf Paus, Wilhelm Bloch, Zu-Lin Chen

Matrix Biol· December 2016

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Activation of the factor XII-driven contact system in Alzheimer's disease patient and mouse model plasma.
Daria Zamolodchikov, Zu-Lin Chen, Brooke A Conti, Thomas Renné, Sidney Strickland

Proc Natl Acad Sci U S A· March 2015

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Prognostic value of PPM1D in 800 gastric cancer patients.
Dan Ma, Chao-Jun Zhang, Zu-Lin Chen, Hua Yang

Mol Med Rep· July 2014

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Astrocytic laminin regulates pericyte differentiation and maintains blood brain barrier integrity.
Yao Yao, Zu-Lin Chen, Erin H Norris, Sidney Strickland

Nat Commun· March 2014

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Ablation of astrocytic laminin impairs vascular smooth muscle cell function and leads to hemorrhagic stroke.
Zu-Lin Chen, Yao Yao, Erin H Norris, Anna Kruyer, Odella Jno-Charles

J Cell Biol· July 2013

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Schwann cell myelination requires integration of laminin activities.
Karen K McKee, Dong-Hua Yang, Rajesh Patel, Zu-Lin Chen, Sidney Strickland, Peter D Yurchenco

J Cell Sci· October 2012

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