Publications by authors named "Zuben Sauna"

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Proceedings of the 15 European immunogenicity platform open symposium on immunogenicity of biopharmaceuticals.
Sophie Tourdot, Karien Bloem, Lysie Champion, Anne S De Groot, Axel Ducret, Zuben Sauna

MAbs· December 2025

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The Impact of Cognate Antigen Binding on the FcRn-mediated Transcytosis and Recycling of Monoclonal Antibodies.
Sharon Vijayanand, H A Daniel Lagasse, Million A Tegenge, Zuben E Sauna, Basil Golding

AAPS J· December 2025

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Therapeutic implications of synonymous gene recoding: insights into mechanisms controlling protein biogenesis and activity.
Brian C Lin, Katarzyna I Jankowska, Upendra K Katneni, Randilu Amarasinghe, Nigam Padhiar, Zuben E Sauna

Protein Cell· October 2025

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MHC II MAPPs for High-Confident Immunogenicity Risk Assessment of Biotherapeutics.
Elise Pepermans, Zuben E Sauna, Sofie Pattyn

Methods Mol Biol· October 2025

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Utilization of Machine Learning Approaches for Drug Clearance Prediction and Population Pharmacokinetic Covariate Analysis.
Atul Rawal, Jiayi Ou, Hao Zhu, Zuben Sauna, Million A Tegenge

Clin Transl Sci· September 2025

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Functional Activity and Binding Specificity of Small Ankyrin Repeat Proteins Called Ankyrons Against SARS-CoV-2 Variants.
Yun-Jong Park, Wojciech Jankowski, Nicholas C Hurst, Jeremy W Fry, Nikolai F Schwabe, Zuben E Sauna

AAPS J· March 2025

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Application of machine learning approaches for predicting hemophilia A severity.
Atul Rawal, Christopher Kidchob, Jiayi Ou, Zuben E Sauna

J Thromb Haemost· July 2024

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Engineering and evaluation of FXa bypassing agents that restore hemostasis following Apixaban associated bleeding.
Wojciech Jankowski, Stepan S Surov, Nancy E Hernandez, Atul Rawal, Marcos Battistel, Zuben E Sauna

Nat Commun· May 2024

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Investigation of thrombin concentration at the time of clot formation in simultaneous thrombin and fibrin generation assays.
Ivan D Tarandovskiy, Stepan S Surov, Leonid A Parunov, Yideng Liang, Wojciech Jankowski, Zuben E Sauna

Sci Rep· April 2024

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Factor VIII moiety of recombinant Factor VIII Fc fusion protein impacts Fc effector function and CD16 NK cell activation.
H A Daniel Lagassé, Jiayi Ou, Zuben E Sauna, Basil Golding

Front Immunol· April 2024

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Dose optimization of an adjuvanted peptide-based personalized neoantigen melanoma vaccine.
Wencel Valega-Mackenzie, Marisabel Rodriguez Messan, Osman N Yogurtcu, Ujwani Nukala, Zuben E Sauna

PLoS Comput Biol· March 2024

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Proceedings of the 14th European immunogenicity platform open symposium on immunogenicity of biopharmaceuticals.
Sophie Tourdot, Daniel Baltrunkonis, Sofie Denies, Viswanath Devanarayan, Joanna Grudzinska-Goebel, Zuben Sauna

MAbs· March 2024

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Emerging approaches to induce immune tolerance to therapeutic proteins.
Justine C Noel, Daniel Lagassé, Basil Golding, Zuben E Sauna

Trends Pharmacol Sci· December 2023

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The MHC Associated Peptide Proteomics assay is a useful tool for the non-clinical assessment of immunogenicity.
Wojciech Jankowski, Christopher Kidchob, Campbell Bunce, Edward Cloake, Ricardo Resende, Zuben E Sauna

Front Immunol· November 2023

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Endotoxin contamination in commercially available Cas9 proteins potentially induces T-cell mediated responses.
Vijaya L Simhadri, Joseph R McGill, Zuben E Sauna

Gene Ther· August 2023

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Corrigendum to "Computational design of nanomolar-binding antibodies specific to multiple SARS-CoV-2 variants by engineering a specificity switch of antibody 80R using RosettaAntibodyDesign (RAbD) results in potential generalizable therapeutic antibodies for novel SARS-CoV-2 virus" [Heliyon 9(4) (April 2023) e15032].
Nancy E Hernandez, Wojciech Jankowski, Rahel Frick, Simon P Kelow, Joseph H Lubin, Zuben E Sauna

Heliyon· August 2023

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Pharmacokinetics of antibodies during Pregnancy: Impact of pregnancy on the pharmacokinetics of antibodies (Part 2).
Million A Tegenge, Iftekhar Mahmood, Evi B Struble, Zuben Sauna

Int Immunopharmacol· June 2023

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Understanding preclinical and clinical immunogenicity risks in novel biotherapeutics development.
Zuben E Sauna, Vibha Jawa, Sathy Balu-Iyer, Narendra Chirmule

Front Immunol· June 2023

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A machine learning approach for identifying variables associated with risk of developing neutralizing antidrug antibodies to factor VIII.
Atul Rawal, Christopher Kidchob, Jiayi Ou, Osman N Yogurtcu, Hong Yang, Zuben E Sauna

Heliyon· June 2023

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Pharmacokinetics of antibodies during pregnancy: General pharmacokinetics and pregnancy related physiological changes (Part 1).
Million A Tegenge, Iftekhar Mahmood, Evi B Struble, Zuben Sauna

Int Immunopharmacol· April 2023

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Computational design of nanomolar-binding antibodies specific to multiple SARS-CoV-2 variants by engineering a specificity switch of antibody 80R using RosettaAntibodyDesign (RAbD) results in potential generalizable therapeutic antibodies for novel SARS-CoV-2 virus.
Nancy E Hernandez, Wojciech Jankowski, Rahel Frick, Simon P Kelow, Joseph H Lubin, Zuben E Sauna

Heliyon· April 2023

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Summary of a Public FDA Workshop: Model Informed Drug Development Approaches for Immunogenicity Assessments.
Artur A Belov, Marisabel Rodriguez Messan, Osman N Yogurtcu, Kimberly Schultz, Kimberly Maxfield, Zuben E Sauna

Clin Pharmacol Ther· February 2023

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A Retrospective Review of Center for Biologics Evaluation and Research Advisory Committee Meetings in the Context of the FDA's Benefit-Risk Framework.
Jane Namangolwa Mutanga, Ujwani Nukala, Marisabel Rodriguez Messan, Osman N Yogurtcu, Quinn McCormick, Zuben E Sauna

AAPS J· February 2023

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Structural, functional, and immunogenicity implications of F9 gene recoding.
Upendra K Katneni, Aikaterini Alexaki, Ryan C Hunt, Nobuko Hamasaki-Katagiri, Gaya K Hettiarachchi, Zuben E Sauna

Blood Adv· July 2022

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A structural homology approach to identify potential cross-reactive antibody responses following SARS-CoV-2 infection.
Joseph R McGill, H A Daniel Lagassé, Nancy Hernandez, Louis Hopkins, Wojciech Jankowski, Zuben E Sauna

Sci Rep· July 2022

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