March 1999 PMID 10049982

High glycemic index foods, overeating, and obesity.

D S Ludwig, J A Majzoub, A Al-Zahrani, G E Dallal, I Blanco, S B Roberts

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Mentions

194
Peak: 48 in Oct 2023
across 5 sources since Jul 2019

Extended reach

1,813,008
potential audience

Total likes

451

Video views

4,542

Mentions per month

Jul 2019 – Sep 2025

Where it's discussed

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AI synopsis

What people are saying

The group demonstrates strong agreement with the publication by referencing multiple scientific studies, sharing detailed hormonal mechanisms like insulin's role in promoting overeating, and discussing practical dietary tips such as starting the day with fats and proteins. The tone strikes a balance between scientific curiosity and skepticism, with some dismissing certain findings or emphasizing methodological debates, which highlights the significance of this topic in ongoing conversations about obesity and diet.

AgreementStrong agreement

Most discussions support the idea that high glycemic index foods promote overeating and hormonal changes linked to obesity, reflecting strong agreement with the publication’s findings.

InterestHigh interest

There is high interest shown by numerous posters referencing studies, sharing data, and discussing mechanisms like insulin and glucagon, indicating deep engagement.

EngagementModerate engagement

While many participants cite research and provide detailed explanations, some dismiss the results or question methodology, suggesting balanced but mainly thoughtful discourse.

ImpactHigh impact

The widespread sharing of the study, referencing of historical experiments, and debates about dietary strategies show that these discussions could influence public understanding and possibly dietary choices, representing significant impact.

Abstract in brief

  • The study investigated how different glycemic index (GI) levels in meals (low, medium, high) affect energy metabolism and food intake in obese teenage boys, finding that high-GI meals lead to a significant increase in voluntary food intake.
  • High-GI meals caused hormonal and metabolic changes such as increased serum insulin, lower glucagon, and elevated epinephrine, which are linked to higher calorie consumption post-meal.
  • The results suggest that consuming high-GI foods may promote overeating in obese individuals due to rapid glucose absorption and related hormonal responses, highlighting the need for further research on GI's role in long-term weight regulation.]

Top posts

Most liked on X and Bluesky
DoctorTro
@DoctorTro · X

Oct 5, 2023 · 252 likes · 50 shares · 163,978 followers View post →
Dr. David Ludwig
@davidludwigmd · X

@CaryKelly11 Here's the original study for those interested in the deep dive (abstract available, full text behind a paywall, unfortunately). Key figures below https://t.co/VwZaCzPxZZ https://t.co/a4ZkantQjo

Jul 16, 2024 · 35 likes · 4 shares · 43,694 followers View post →
DoctorTro
@DoctorTro · X

There was literally a double blind controlled study done in 1999 that tested the satiety of exactly these two meals And the results were in stark contrast to what is being presented Fiat satiety scores are not the way This is so embarassing I can’t https://t.co/KELrUgrce7 https://t.co/TfLN0oVtFF https://t.co/TQNF2yxHP3

Apr 6, 2024 · 23 likes · 4 shares · 163,978 followers View post →
Dr. David Ludwig
@davidludwigmd · X

@nicknorwitz My first clinical trial looked at this point, back when I was only a bit older than you, @nicknorwitz (done in 1996, but took 3 years to publish) https://t.co/VwZaCzPxZZ

Mar 30, 2024 · 21 likes · 2 shares · 43,694 followers View post →
Dr. David Ludwig
@davidludwigmd · X

@JohnSpeakman4 @gfj1979 @BenBikmanPhD @JimJohnsonSci Let's make this easy, John. Links to some of our articles considering insulin relative to glucagon for fat storage: https://t.co/lsX68yIsPI https://t.co/YAiK1iQEk1 https://t.co/xDosEmFSFv https://t.co/5Xsdqy3xeM https://t.co/SNtThjPbPd https://t.co/z3LVoJEiwl A handy collage

Mar 3, 2020 · 20 likes · 5 shares · 43,694 followers View post →
Mike - Low Carb Dietitian
@thelowcarb_rd · X

@IvicaMaslaceti https://t.co/v3ek26Vsqd

Feb 10, 2025 · 7 likes · 15,983 followers View post →

All mentions

科学的サボり魔 【科学で人生変えたコーチ】
@bonjinstrategy · X

成功している人ほど「血糖スパイク」を避ける 食後の急激な血糖上昇(血糖スパイク)は、疲労感や集中力低下を招くと報告されています。 (参考: https://t.co/pFGLMgvcFj) キャリアを走り抜くには、まず“安定したエネルギー供給”が必須です。 目安は食事後に眠いなら糖質過多な食生活になりがちな証拠

Sep 20, 2025 · 38 followers View post →
科学的サボり魔 【科学で人生変えたコーチ】
@bonjinstrategy · X

『成功している人ほど「朝食の質」にこだわる』 ハーバード大学の研究では、高GIの朝食は午後の集中力を低下させることが示されています。 (参考: https://t.co/pFGLMguEPL) キャリアを伸ばしたいなら、まずは血糖コントロールから。成功の土台は食事にあります。

Sep 18, 2025 · 38 followers View post →
DoctorTro
@DoctorTro · X

@lowcarbGP @BenBikmanPhD @drjasonfung @KenDBerryMD @BrownAdey From our friend @davidludwigmd https://t.co/KELrUgrce7 https://t.co/pLTmqjvIxo

May 23, 2025 · 4 likes · 163,978 followers View post →
John Speakman
@JohnSpeakman4 · X

@garytaubes @Maratosflier @ethanjweiss @JohnSpeakman Here is the link to the Ludwig paper. But I apologise because it was published before Twitter existed so you didn't get chance to slag it off. Still you have the opportunity now. It has been cited >1000x so many think it is a valid and definitive test. https://t.co/brI8nvxGia

Mar 6, 2025 · 6 likes · 11,994 followers View post →
Mike - Low Carb Dietitian
@thelowcarb_rd · X

@IvicaMaslaceti https://t.co/v3ek26Vsqd

Feb 10, 2025 · 7 likes · 15,983 followers View post →
Malki Zeee
@malkizeee · X

RT @davidludwigmd: @CaryKelly11 Here's the original study for those interested in the deep dive (abstract available, full text behind a pay…

Jul 17, 2024 · 4 shares · 542 followers View post →
keto3000
@keto3000 · X

RT @davidludwigmd: @CaryKelly11 Here's the original study for those interested in the deep dive (abstract available, full text behind a pay…

Jul 16, 2024 · 4 shares · 446 followers View post →
Wankio Nyainda
@WankioNyainda · X

RT @davidludwigmd: @CaryKelly11 Here's the original study for those interested in the deep dive (abstract available, full text behind a pay…

Jul 16, 2024 · 4 shares · 681 followers View post →
Cary Kelly
@CaryKelly11 · X

RT @davidludwigmd: @CaryKelly11 Here's the original study for those interested in the deep dive (abstract available, full text behind a pay…

Jul 16, 2024 · 4 shares · 67,478 followers View post →
Dr. David Ludwig
@davidludwigmd · X

@CaryKelly11 Here's the original study for those interested in the deep dive (abstract available, full text behind a paywall, unfortunately). Key figures below https://t.co/VwZaCzPxZZ https://t.co/a4ZkantQjo

Jul 16, 2024 · 35 likes · 4 shares · 43,694 followers View post →
Jesse Eureste
@jeureste13 · X

RT @DoctorTro: There was literally a double blind controlled study done in 1999 that tested the satiety of exactly these two meals And th…

Apr 8, 2024 · 4 shares · 410 followers View post →
Mad
@MadPharmacist1 · X

RT @DoctorTro: There was literally a double blind controlled study done in 1999 that tested the satiety of exactly these two meals And th…

Apr 7, 2024 · 4 shares · 6,465 followers View post →
Messner
@_messner · X

RT @DoctorTro: There was literally a double blind controlled study done in 1999 that tested the satiety of exactly these two meals And th…

Apr 6, 2024 · 4 shares · 59 followers View post →
Glenn Fincher
@gtfinchy · X

RT @DoctorTro: There was literally a double blind controlled study done in 1999 that tested the satiety of exactly these two meals And th…

Apr 6, 2024 · 4 shares · 3,261 followers View post →
DoctorTro
@DoctorTro · X

There was literally a double blind controlled study done in 1999 that tested the satiety of exactly these two meals And the results were in stark contrast to what is being presented Fiat satiety scores are not the way This is so embarassing I can’t https://t.co/KELrUgrce7 https://t.co/TfLN0oVtFF https://t.co/TQNF2yxHP3

Apr 6, 2024 · 23 likes · 4 shares · 163,978 followers View post →
Candice Vader
@vadercandice · X

RT @davidludwigmd: @nicknorwitz My first clinical trial looked at this point, back when I was only a bit older than you, @nicknorwitz (done…

Mar 30, 2024 · 2 shares · 224 followers View post →
SAVE AMERICA
@1718106J · X

RT @davidludwigmd: @nicknorwitz My first clinical trial looked at this point, back when I was only a bit older than you, @nicknorwitz (done…

Mar 30, 2024 · 2 shares · 9,774 followers View post →
Dr. David Ludwig
@davidludwigmd · X

@nicknorwitz My first clinical trial looked at this point, back when I was only a bit older than you, @nicknorwitz (done in 1996, but took 3 years to publish) https://t.co/VwZaCzPxZZ

Mar 30, 2024 · 21 likes · 2 shares · 43,694 followers View post →
eleanorina
@_eleanorina · X

RT @LCMDPodcast: @mario_kratz @TheBhupiThakur @davidbirsen @KevinH_PhD 20mg/dl initiates brain reward - https://t.co/bzHqKhZ5aq Here is…

Mar 23, 2024 · 1 share · 3,179 followers View post →
LowCarbMD Podcast
@LCMDPodcast · X

@mario_kratz @TheBhupiThakur @davidbirsen @KevinH_PhD 20mg/dl initiates brain reward - https://t.co/bzHqKhZ5aq Here is well controlled study https://t.co/x5rpoJNjSO GI graded diets https://t.co/SuxzgEuuVZ Happy to share more - you’d need to unblock me @doctortro

Mar 23, 2024 · 1 share · 11,848 followers View post →
Bradley Chillerman, PhD
@BroChillerman · X

@mario_kratz Only one that comes to mind is this one where the moderate and high GI have the same protein % https://t.co/rZAio0odYf

Mar 22, 2024 · 361 followers View post →
Vegay
@psoriasian · X

@BraciaRodzen Owsianka > jajecznica https://t.co/8lweXUjeOf https://t.co/BPUFz8lbRO https://t.co/4HTd9cfYqT https://t.co/fyVH3dvZXa https://t.co/R2Mzm2Tphx

Jan 21, 2024 · 17 followers View post →
michael r barrett
@zaailor · X

@miSIXeWay @fmanjoo @katieunderwrite @PeterAttiaMD @RandyNesse @hubermanlab @Sydney_Uni @brish_ti @CMA_Docs @IoannaCBC @witmer_brenda @ISBLeeHood @Giuliaaaa99 @NickKristof @Ethan_Lou @MikeSandclan @priyakrishna @cfrangou @GriebelerMD @carlyweeks @NavPersaud @FryRsquared @davechokshi @markhollandlib @adriandix @By_CJewett @marcusbgee @glendaluymes @billmaher @nytimeswell @ShaneGoldmacher @dwallacewells @JessicaRotondi @JPTasker @nutrition_facts @rcarrick @IlonaHale @DrHelenOuyang @PeterHotez @cjsaffitzstan @BajkaBalazs @ProfGlantz @patrickholford @MayMf1111 @davidludwigmd @NicholasLBarber @jbsgreenberg @sarahkliff @Oprah Is #Obesity a disease when “the rapid absorption of glucose after consumption of HIGH GI MEALS induces a sequence of hormonal & metabolic changes that PROMOTE EXCESSIVE FOOD INTAKE”? From https://t.co/2rCwjG8nD0. @davidludwigmd explains in video https://t.co/0gMAD

Jan 19, 2024 · 108 followers View post →
Socca
@VirBrok · X

RT @DoctorTro:

Dec 16, 2023 · 50 shares · 119 followers View post →
MindBodyDad
@MindBodyDad · X

Manage those blood sugar swings. Read the study here: https://t.co/UFQ4IwE3BU https://t.co/CsEYEPsXXB

Nov 8, 2023 · 26 followers View post →
Cure Naturally LLC
@CureNaturally · X

RT @DoctorTro:

Oct 23, 2023 · 50 shares · 1,026 followers View post →
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@healOMF · X

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Oct 12, 2023 · 50 shares · 191 followers View post →
Brushfyre Marketing
@BrushfyreMB · X

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Oct 8, 2023 · 50 shares · 2,473 followers View post →
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@VasiiHoratiu · X

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Oct 8, 2023 · 50 shares · 484 followers View post →
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@bocajoes · X

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Wilhelm Visser
@Visser2Wilhelm · X

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Oct 7, 2023 · 50 shares · 563 followers View post →
Stephen Thomas BSc Hons
@UKcarnivore · X

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Oct 7, 2023 · 50 shares · 2,224 followers View post →
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@JJayjj22 · X

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Oct 7, 2023 · 50 shares · 8 followers View post →
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@OecSmith · X

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@LKikez · X

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@KJV0614 · X

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@atchison_dean · X

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@RyteWynger · X

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dankbubba, #TRUMP2024 #MAGA
@dank1j · X

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@drjasonfung · X

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@WhizdomOver · X

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@Mary61277319 · X

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@Common_SenseCO · X

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@Andykk2012 · X

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@ProfTimNoakes · X

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@TorstiSami · X

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@JJWUrology · X

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@carbaddictcoach · X

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@max_ev_84 · X

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@DaveWBrowning · X

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@RedGhostLover · X

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@ManagerDairy · X

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@StefanusSnyman · X

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@_HOLO_FUEL_ · X

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@DeeVille6 · X

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@HarryVig1 · X

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@gmericanite · X

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@MonjeLucax · X

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@RhanBlaze · X

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@stevieb99 · X

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@shekinah1313 · X

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@NobiesseLabs · X

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vern thompson 3rd times a charm
@VernThomp47616 · X

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Don't Try It
@ImUngovernable · X

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Dr Murphy WeightLoss
@TakeWeightOffMD · X

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Hector de Trois
@Hector_de_3 · X

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Oct 5, 2023 · 50 shares · 1,011 followers View post →
Mad
@MadPharmacist1 · X

RT @DoctorTro:

Oct 5, 2023 · 50 shares · 6,465 followers View post →
Cheryl
@CherylRNRetired · X

RT @DoctorTro:

Oct 5, 2023 · 50 shares · 847 followers View post →
DoctorTro
@DoctorTro · X

Oct 5, 2023 · 252 likes · 50 shares · 163,978 followers View post →
Julianne Taylor, Nutritionist
@juliannejtaylor · X

@theproof Although they talk about insulin driving fat storage, driving overeating. High carb incr insulin, inc glucose disposal from blood, -> incr hunger -> overeating. Low protein, no glucagon. Different macros in low GI and high GI despite what abstract says. https://t.co/2b03VwjjpS

Apr 19, 2023 · 5,293 followers View post →
DoctorTro
@DoctorTro · X

@Richk515 https://t.co/KELrUgrce7

Jan 18, 2023 · 163,978 followers View post →
LibKey
@libkey_io · X

@DoctorTro @tednaiman @DrEenfeldt @JohnSpeakman4 @KevinH_PhD Access the paywalled article from your library: https://t.co/GhGst97K5N Promote scholarly access to content by simply adding https://t.co/SXSePTeGuM to the DOI URL

Jun 25, 2022 · 553 followers View post →
DoctorTro
@DoctorTro · X

@tednaiman @DrEenfeldt @JohnSpeakman4 @KevinH_PhD Even more data https://t.co/KELrUgIN5F

Jun 25, 2022 · 4 likes · 163,978 followers View post →
Dr. David Ludwig
@davidludwigmd · X

@CarolMeinhart @MichelleHurnRD Actually, one arm did (an egg omelet): https://t.co/VwZaCzPxZZ

Feb 20, 2022 · 2 likes · 43,694 followers View post →
Jason Loera
@fastreps · X

3 different groups. 3 different breakfasts (Same exact calories): 1. Instant oatmeal 2. Steel-cut oats 3. Omelette Instant oatmeal group ate 81% more food than the omelette group Take home: ✅ Start your day off with fats & proteins ❌ Not carbohydrates https://t.co/VBj1w4syA4

Jan 20, 2022 · 1,176 followers View post →
Simon Dankel
@simondankel · X

RT @davidludwigmd: @JohnSpeakman4 @gfj1979 @BenBikmanPhD @JimJohnsonSci Let's make this easy, John. Links to some of our articles consideri…

May 1, 2021 · 5 shares · 759 followers View post →
Sure Tips Lord
@Sure_Tips_Lord · X

These signals make you crave more food, and are known to cause overeating (Source (https://t.co/0HgiSFBfE3)).

Apr 30, 2021 · 169 followers View post →
Sure Tips Lord
@Sure_Tips_Lord · X

Because they are low in fiber and digested quickly, eating refined carbs can cause major swings in blood sugar levels. This can contribute to overeating (Source (https://t.co/0HgiSFBfE3)).

Apr 30, 2021 · 169 followers View post →
محمد القيسي
@MchemistG · X

للمزيد أيضاً يمكن تحميل الأوراق التالية الورقة١/ https://t.co/Psh7gKQKv5 الورقة٢/ https://t.co/wfAOHC36xX الورقة٣/ https://t.co/bRQCz5mYv0 الورقة٤/ https://t.co/bdi8Wj3pca الورقة٥/ https://t.co/R0j9nCOyxG https://t.co/vWslm4An8r

Aug 22, 2020 · 7 likes · 15,348 followers View post →
Boris Dufournet MD
@BDufournet · X

RT @davidludwigmd: @JohnSpeakman4 @gfj1979 @BenBikmanPhD @JimJohnsonSci Let's make this easy, John. Links to some of our articles consideri…

Mar 3, 2020 · 5 shares · 355 followers View post →
Ellen Wetherill
@afashionfan · X

RT @davidludwigmd: @JohnSpeakman4 @gfj1979 @BenBikmanPhD @JimJohnsonSci Let's make this easy, John. Links to some of our articles consideri…

Mar 3, 2020 · 5 shares · 2,246 followers View post →
DoctorTro
@DoctorTro · X

RT @davidludwigmd: @JohnSpeakman4 @gfj1979 @BenBikmanPhD @JimJohnsonSci Let's make this easy, John. Links to some of our articles consideri…

Mar 3, 2020 · 5 shares · 163,978 followers View post →
Peter Voshol
@Peter_Voshol · X

RT @davidludwigmd: @JohnSpeakman4 @gfj1979 @BenBikmanPhD @JimJohnsonSci Let's make this easy, John. Links to some of our articles consideri…

Mar 3, 2020 · 5 shares · 1,890 followers View post →
Dr. David Ludwig
@davidludwigmd · X

@JohnSpeakman4 @gfj1979 @BenBikmanPhD @JimJohnsonSci Let's make this easy, John. Links to some of our articles considering insulin relative to glucagon for fat storage: https://t.co/lsX68yIsPI https://t.co/YAiK1iQEk1 https://t.co/xDosEmFSFv https://t.co/5Xsdqy3xeM https://t.co/SNtThjPbPd https://t.co/z3LVoJEiwl A handy collage

Mar 3, 2020 · 20 likes · 5 shares · 43,694 followers View post →
Daniel Montero
@ndanmontero · X

High Glycemic Index Foods, Overeating, and Obesity Pediatrics March 1999, VOLUME 103 / ISSUE 3 https://t.co/oHrbbxZgjm

Jul 18, 2019 · 4,668 followers View post →