Proc Natl Acad Sci U S A January 2001 PMID 11209064

A default mode of brain function.

M E Raichle, A M MacLeod, A Z Snyder, W J Powers, D A Gusnard, G L Shulman

Mentions

151
Peak: 10 in Feb 2024
across 5 sources since Feb 2019

Extended reach

136,301
potential audience

Total likes

2,605

Video views

44,105

Mentions per month

Feb 2019 – Oct 2025

Where it's discussed

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AI synopsis

What people are saying

The overall tone reflects high interest and deep engagement, as users discuss how the default mode network (DMN) operates during resting states, referencing key studies like Raichle et al. (2001). Words like 'perpetually active,' 'baseline,' and 'organized default mode' reveal an appreciation for the article's explanation of brain activity and its importance for understanding cognition, which collectively contribute to perceiving it as impactful in neuroscience.

AgreementModerate agreement

Many discussions acknowledge the significance of the research, with some explicitly supporting its findings, though a few express skepticism or need for clarification.

InterestHigh interest

Posts demonstrate high curiosity about the default mode of brain function, with mentions of its relevance to mental states and the brain's activity during rest.

EngagementHigh engagement

Several comments cite specific studies, historical context, and implications, indicating deep engagement with the material and its broader significance.

ImpactModerate impact

The discussions suggest that this publication is viewed as influential, sparking ongoing conversations about brain activity, default states, and their relevance to self-referential and cognitive processes.

Abstract in brief

  • The study identifies a baseline or default state of brain activity in the awake, resting human brain, measured through the oxygen extraction fraction (OEF), which remains relatively uniform but shows localized deviations during specific behaviors.
  • These deviations are mainly increases in OEF indicating deactivations, especially in the visual system, and are fundamental to understanding how brain activity shifts during goal-directed tasks.
  • The findings suggest that there is an organized default mode of brain function that is active during rest and is suspended when engaging in goal-oriented behaviors, highlighting the importance of this baseline state for brain function.]

Top posts

Most liked on X and Bluesky
ゆきまさかずよし
@Kyukimasa · X

なにも考えてない時は脳の血流は下がってるから負荷かかる処理やってるわけじゃないけど、特有の脳活動DMN(default mode network)がある https://t.co/5yLoKrzLXG 関連兼研究(2009年)では浅い眠りだとDMNは持続してるが深い眠りでは切れるとかあって、思考や意識の基礎に近いみたいだ

Feb 7, 2024 · 27 likes · 10 shares · 20,438 followers View post →
thmonk
@thmonk_pf · X

RichleのDMという単語を用いた最初の論文 脳の特定領域がタスクに関係なく一貫して活動低下に関与していることからdefault modeとして存在し特定の目標に向けた行動時には中断される組織的な脳機能様式が存在するのではないかと考えた Open Access #DMN #fMRI #papers https://t.co/AACPpLmUVJ https://t.co/iYI7kd9meJ

May 12, 2023 · 3 likes · 1,632 followers View post →
Shibley
@dr_shibley · X

A default mode of brain function https://t.co/1WpwUVMGas

Jun 20, 2020 · 2 likes · 1 share · 27,495 followers View post →
Matt
@mjjk_matt · X

@itsplato7 @springpard

Oct 3, 2024 · 1 like · 1,927 followers View post →
naman mathur
@Naman__M · X

@karthi2209 So true, several experiments have proven its vitality ✨ "A 2001 study defined a “default mode” of brain function that showed that even when the brain was “resting” it was perpetually active internalizing and evaluating information." https://t.co/yti9zwNRm3 Via @lifehackorg

Sep 20, 2020 · 1 like · 861 followers View post →
RePsynapse
@RePsynapse · X

15/15 Sources and Further Reading: • Raichle, M. E. (2001). A default mode of brain function • Carhart-Harris, R. L., & Friston, K. J. (2010). The default-mode, ego functions, and free energy • Hume, D. (1739). A Treatise of Human Nature • Brewer, J. A. et al. (2011).

Jun 5, 2025 · 1 like · 346 followers View post →

All mentions

arvin15
@the__Arvin_1 · X

@ah1_200 @mol7d_Arabi Raichle et al. (2001). A default mode of brain function, PNAS. https://t.co/p6otD9UhbK

Jun 19, 2025 · 134 followers View post →
arvin15
@the__Arvin_1 · X

@ah1_200 @mol7d_Arabi Raichle, M. E. et al. (2001). A default mode of brain function. PNAS. أول من وصف الشبكة الافتراضية للدماغ المرتبطة بالإحساس بالذات والوعي الداخلي. إذًا: الوعي مش "لغز مطلق"، بل ظاهرة عصبية قابلة للرصد والتفسير التدريجي.

Jun 19, 2025 · 134 followers View post →
RePsynapse
@RePsynapse · X

15/15 Sources and Further Reading: • Raichle, M. E. (2001). A default mode of brain function • Carhart-Harris, R. L., & Friston, K. J. (2010). The default-mode, ego functions, and free energy • Hume, D. (1739). A Treatise of Human Nature • Brewer, J. A. et al. (2011).

Jun 5, 2025 · 1 like · 346 followers View post →
ふくお先生@行動する脳科学
@Dr_Fukuo · X

Raichle et al. (2001) Default mode network:何もしてない時に活発に働く脳領域 → 自己反省・感情の整理・記憶の統合などに関与 https://t.co/YsIoQdK9qJ

May 4, 2025 · 1,478 followers View post →
ふくお先生@行動する脳科学
@Dr_Fukuo · X

参考文献 Raichle et al. (2001) Default Mode Network: ぼーっとしてるときに脳が最も活動している領域 → https://t.co/YsIoQdKHgh

May 3, 2025 · 1,478 followers View post →
ふくお先生@行動する脳科学
@Dr_Fukuo · X

【参考文献】 1.Raichle, M. E. et al. (2001) “A default mode of brain function.” PNAS → デフォルトモード・ネットワーク(DMN)は、何もしていない時に活性化し、自己反省・記憶の整理などに関与。 https://t.co/YsIoQdKHgh

May 2, 2025 · 1,478 followers View post →
SF
@Steephen_Falken · X

@andrzejdragan @JemielniakD https://t.co/AqHbCDnD4I

Dec 23, 2024 · 1 like · 40 followers View post →
Matt
@mjjk_matt · X

@itsplato7 @springpard

Oct 3, 2024 · 1 like · 1,927 followers View post →
hiro
@goldisthemetal · X

RT @Kyukimasa: なにも考えてない時は脳の血流は下がってるから負荷かかる処理やってるわけじゃないけど、特有の脳活動DMN(default mode network)がある https://t.co/5yLoKrzLXG 関連兼研究(2009年)では浅い眠りだとDMN…

Feb 8, 2024 · 10 shares · 872 followers View post →
至
@itacccchi · X

RT @Kyukimasa: なにも考えてない時は脳の血流は下がってるから負荷かかる処理やってるわけじゃないけど、特有の脳活動DMN(default mode network)がある https://t.co/5yLoKrzLXG 関連兼研究(2009年)では浅い眠りだとDMN…

Feb 8, 2024 · 10 shares · 393 followers View post →
緑姐/luzie(完璧万能手)
@luzie0311 · X

RT @Kyukimasa: なにも考えてない時は脳の血流は下がってるから負荷かかる処理やってるわけじゃないけど、特有の脳活動DMN(default mode network)がある https://t.co/5yLoKrzLXG 関連兼研究(2009年)では浅い眠りだとDMN…

Feb 7, 2024 · 10 shares · 297 followers View post →
Emilie és Édouard
@ski7glsoox · X

RT @Kyukimasa: なにも考えてない時は脳の血流は下がってるから負荷かかる処理やってるわけじゃないけど、特有の脳活動DMN(default mode network)がある https://t.co/5yLoKrzLXG 関連兼研究(2009年)では浅い眠りだとDMN…

Feb 7, 2024 · 10 shares · 316 followers View post →
まゆのあお
@mayunoao_as · X

RT @Kyukimasa: なにも考えてない時は脳の血流は下がってるから負荷かかる処理やってるわけじゃないけど、特有の脳活動DMN(default mode network)がある https://t.co/5yLoKrzLXG 関連兼研究(2009年)では浅い眠りだとDMN…

Feb 7, 2024 · 10 shares · 864 followers View post →
HARUKA【杳】若月
@kxy4427 · X

RT @Kyukimasa: なにも考えてない時は脳の血流は下がってるから負荷かかる処理やってるわけじゃないけど、特有の脳活動DMN(default mode network)がある https://t.co/5yLoKrzLXG 関連兼研究(2009年)では浅い眠りだとDMN…

Feb 7, 2024 · 10 shares · 298 followers View post →
Takar
@ta_kar · X

RT @Kyukimasa: なにも考えてない時は脳の血流は下がってるから負荷かかる処理やってるわけじゃないけど、特有の脳活動DMN(default mode network)がある https://t.co/5yLoKrzLXG 関連兼研究(2009年)では浅い眠りだとDMN…

Feb 7, 2024 · 10 shares · 1,258 followers View post →
Notintelli_Inc.
@notintelli_inc · X

RT @Kyukimasa: なにも考えてない時は脳の血流は下がってるから負荷かかる処理やってるわけじゃないけど、特有の脳活動DMN(default mode network)がある https://t.co/5yLoKrzLXG 関連兼研究(2009年)では浅い眠りだとDMN…

Feb 7, 2024 · 10 shares · 1,269 followers View post →
そうは、い観世音菩薩@GPT
@iruka3 · X

RT @Kyukimasa: なにも考えてない時は脳の血流は下がってるから負荷かかる処理やってるわけじゃないけど、特有の脳活動DMN(default mode network)がある https://t.co/5yLoKrzLXG 関連兼研究(2009年)では浅い眠りだとDMN…

Feb 7, 2024 · 10 shares · 1,950 followers View post →
ゆきまさかずよし
@Kyukimasa · X

なにも考えてない時は脳の血流は下がってるから負荷かかる処理やってるわけじゃないけど、特有の脳活動DMN(default mode network)がある https://t.co/5yLoKrzLXG 関連兼研究(2009年)では浅い眠りだとDMNは持続してるが深い眠りでは切れるとかあって、思考や意識の基礎に近いみたいだ

Feb 7, 2024 · 27 likes · 10 shares · 20,438 followers View post →
marcelotrajano
@marcelotrajano · X

A default mode of brain function | PNAS https://t.co/Bs5zM1Z2Gp

Jul 25, 2023 · 41 followers View post →
thmonk
@thmonk_pf · X

RichleのDMという単語を用いた最初の論文 脳の特定領域がタスクに関係なく一貫して活動低下に関与していることからdefault modeとして存在し特定の目標に向けた行動時には中断される組織的な脳機能様式が存在するのではないかと考えた Open Access #DMN #fMRI #papers https://t.co/AACPpLmUVJ https://t.co/iYI7kd9meJ

May 12, 2023 · 3 likes · 1,632 followers View post →
Medical Xpress
@physorg_health · X

How your #brain decides what to think @ConversationEDU https://t.co/4RJ9aIBOZ5 https://t.co/0mH66NdL8v

Feb 21, 2023 · 7,101 followers View post →
Eric J Feczko
@EricFeczko · X

@WiringTheBrain @blamlab @PessoaBrain @ndosenbach @malcolmmaciver @LucinaUddin Except Randy Buckner didn’t name the default-mode network. https://t.co/SCOMnZtCK9 It was called the default-mode because it reflected a baseline condition for functional activation ( e.g. eyes closed and resting awake ) https://t.co/gNk6PTcLtI

Oct 29, 2022 · 544 followers View post →
Steve
@stevenratltner · X

"A default mode of #brain #function" | Proceedings of the National Academy of Sciences" https://t.co/ZVLH8GdZC5

Aug 13, 2022 · 4,188 followers View post →
Jordan James Etem
@JordanJamesEtem · X

Gusnard DA, Akbudak E, Shulman GL, Raichle ME (2001) Medial prefrontal cortex and self-referential mental activity: relation to a default mode of brain function. Proc Natl Acad Sci U S A 98:4259–4264. doi: 10.1073/pnas.071043098 @taylorswift13 #Mindset https://t.co/Co30utYGCM

Aug 7, 2021 · 12,643 followers View post →
naman mathur
@Naman__M · X

@karthi2209 So true, several experiments have proven its vitality ✨ "A 2001 study defined a “default mode” of brain function that showed that even when the brain was “resting” it was perpetually active internalizing and evaluating information." https://t.co/yti9zwNRm3 Via @lifehackorg

Sep 20, 2020 · 1 like · 861 followers View post →
karenk_____
@karenk_____ · X

RT @dr_shibley: A default mode of brain function https://t.co/1WpwUVMGas

Jun 20, 2020 · 1 share · 895 followers View post →
Shibley
@dr_shibley · X

A default mode of brain function https://t.co/1WpwUVMGas

Jun 20, 2020 · 2 likes · 1 share · 27,495 followers View post →
Ronald Munodawafa
@RonaldTinasheM · X

A default mode of brain function https://t.co/xbEg3kJg5g

Jun 8, 2019 · 57 followers View post →
Lisa Hazelgrove
@belisahealthy · X

In a 2001 study defined as a "default mode" of brain function that showed that even when the brain was "resting" it was perpetually active internalizing and evaluating information. https://t.co/Fc8dc0sAlU

Jun 4, 2019 · 165 followers View post →
Michael Dooney
@MichaelDooney_ · X

A default mode of brain function: @PNASNews Marcus E. Raichle, Ann Mary MacLeod, Abraham Z. Snyder, William J. Powers, Debra A. Gusnard, and Gordon L. Shulman https://t.co/TgvIB5md9E

Feb 9, 2019 · 1,287 followers View post →
Timothy Siangdun
@TVSiangdun · X

A 2001 study defined a “default mode” of brain function, explaining that a “resting” brain is still constantly at work, absorbing and evaluating information. https://t.co/S2q5K5slcu

Feb 3, 2019 · 114 followers View post →