Annu Rev Neurosci September 2001 PMID 11283309

An integrative theory of prefrontal cortex function.

E K Miller, J D Cohen

Mentions

121
Peak: 24 in Apr 2023
across 5 sources since Nov 2017

Extended reach

310,601
potential audience

Total likes

2,123

Video views

36,734

Mentions per month

Nov 2017 – Oct 2025

Where it's discussed

  • X / Twitter52 posts
  • News41 articles
  • Blogs15 articles
  • YouTube11 videos
  • Bluesky2 posts

AI synopsis

What people are saying

The group shows strong support and fascination with the theory, citing phrases like 'integrative theory,' 'cognitive control,' and references to foundational studies, demonstrating a high level of scholarly engagement and perceived importance across various contexts.

AgreementStrong agreement

Most discussions praise the theory as a comprehensive explanation of prefrontal cortex functions, indicating strong agreement.

InterestHigh interest

The detailed references to key concepts like cognitive control and neural pathways suggest high curiosity and engagement with the material.

EngagementHigh engagement

Posts include references to specific studies, theories, and implications, reflecting deep engagement, such as mentions of how goal maintenance links input, states, and outputs.

ImpactHigh impact

Many discussions highlight the significance of this theory in understanding brain function and its broader influence on neuroscience, technology, and societal issues.

Abstract in brief

  • The prefrontal cortex is crucial for cognitive control, helping us coordinate our thoughts and actions based on internal goals, but scientists have not fully understood how it works at a neural level.
  • The proposed theory suggests that the prefrontal cortex maintains active patterns of activity that represent our goals and strategies, guiding other brain areas to connect inputs and internal states with the correct outputs for any task.
  • Evidence from various scientific studies supports this idea, highlighting the role of the prefrontal cortex in biasing neural pathways and emphasizing the need to explore further how this process operates.]

Top posts

Most liked on X and Bluesky
CLaE
@leafs_s · X

Annual Review of Neuroscience An Integrative Theory of Prefrontal Cortex Function https://t.co/SOIln5axUr

Apr 30, 2023 · 117 likes · 26 shares · 28,042 followers View post →
Earl K. Miller
@MillerLabMIT · X

@CharanRanganath @JohnKubie @postlelab @celestekidd Simply put, executive functions are the collection of mechanisms underlying top-down, goal-directed, behavior. It is a thing because your brain does it. There are lots of reviews but I will plug my own. An oldie but goodie, IMHO. https://t.co/TvtOxjQFhn

Jan 26, 2022 · 33 likes · 2 shares · 41,246 followers View post →
CLaE
@leafs_s · X

Annual Review of Neuroscience (2001) An Integrative Theory of Prefrontal Cortex Function https://t.co/uJAruyRRTW

Jul 29, 2021 · 8 likes · 2 shares · 28,042 followers View post →
CLaE
@claeneuro.bsky.social · Bluesky

Annual Review of Neuroscience An Integrative Theory of Prefrontal Cortex Function www.annualreviews.org/content/jour...

Dec 20, 2024 · 6 likes View post →
⚕ Esme, alias Dra. Molécula
@esmeraldavela · X

Miller EK, Cohen JD. An integrative theory of prefrontal cortex function. Annu Rev Neurosci. 2001;24:167-202. Pope HG, Jr., Yurgelun-Todd D. The residual cognitive effects of heavy marijuana use in college students. JAMA. 1996;275(7):521-7.

Apr 20, 2023 · 5 likes · 3,121 followers View post →
8Eevert ✨
@8Eevert · X

> cognitive control > stems from the prefrontal cortex > active maintenance of goals and means > provide bias signals > establish mappings between inputs, states, and outputs —An integrative theory of prefrontal cortex function. Annu Rev Neurosci. 2001 https://t.co/7BGj5YZ4t2 https://t.co/0ISKClfkeE

Apr 30, 2023 · 3 likes · 1,142 followers View post →

All mentions

Achieving Focus and Clarity for Purposeful Progress

Moving through life assertively means acting with clarity, purpose, and consciousness. Understanding what we truly want aligns decisions with values and goals, reducing wasted energy. Modern psychology shows assertive…

didatics · Oct 20, 2025 6,545 views
arvin15
@the__Arvin_1 · X

@ah1_200 @mol7d_Arabi Miller, E. K., & Cohen, J. D. (2001). An integrative theory of prefrontal cortex function. Annual Review of Neuroscience, 24, 167–202. DOI: 10.1146/annurev.neuro.24.1.167 المصدر

Jun 18, 2025 · 142 followers View post →
some-rss-feeds.bsky.social
@some-rss-feeds.bsky.social · Bluesky

[some-subscribed-rss] New Post: An integrative theory of prefrontal cortex function – PubMed, by Grady https://gwizproductions.info/research/?p=127885

Jun 9, 2025 View post →
sea_1891
@sea_1891 · X

روابط علمية تدعم الكلام: 1: https://t.co/fxnw7VNEhm 2: https://t.co/G6GPR08CSP 3: https://t.co/UEJpgHC467

May 2, 2025 · 171 followers View post →
鈴木就翔 | 夢中戦略家
@NX9esHPiE9OLjdd · X

【柔軟な思考(認知的柔軟性)】 問題解決や適応力の向上に不可欠。 (Miller, E.K., & Cohen, J.D., 2001「An Integrative Theory of Prefrontal Cortex Function」) 新しい視点を取り入れることで、創造性が刺激され、柔軟な思考が革新的なアイデアにつながる(Scott Barry Kaufman などの研究)。 https://t.co/AfdbOdcxb9

Feb 3, 2025 · 2 likes · 114 followers View post →
CLaE
@claeneuro.bsky.social · Bluesky

Annual Review of Neuroscience An Integrative Theory of Prefrontal Cortex Function www.annualreviews.org/content/jour...

Dec 20, 2024 · 6 likes View post →
Mario Senden
@Mario_Senden · X

RT @CCNMaastricht: We continue our 25-year #Neuroscience journey

Feb 6, 2024 · 1 share · 172 followers View post →
Cognitive Computational Neuroscience Maastricht
@CCNMaastricht · X

We continue our 25-year #Neuroscience journey

Feb 5, 2024 · 1 share · 288 followers View post →
Kain Seo
@kainseo17 · X

RT @leafs_s: Annual Review of Neuroscience An Integrative Theory of Prefrontal Cortex Function https://t.co/SOIln5axUr

May 2, 2023 · 26 shares · 27 followers View post →
Andres Tarqui
@AndresTarqui5 · X

RT @leafs_s: Annual Review of Neuroscience An Integrative Theory of Prefrontal Cortex Function https://t.co/SOIln5axUr

May 1, 2023 · 26 shares · 14 followers View post →
GhyzSlvzmjtz
@GhyzSlvzmjtz · X

RT @leafs_s: Annual Review of Neuroscience An Integrative Theory of Prefrontal Cortex Function https://t.co/SOIln5axUr

May 1, 2023 · 26 shares · 233 followers View post →
Brian Odegaard
@BrianOdegaard2 · X

RT @leafs_s: Annual Review of Neuroscience An Integrative Theory of Prefrontal Cortex Function https://t.co/SOIln5axUr

May 1, 2023 · 26 shares · 1,162 followers View post →
CLaE
@leafs_s · X

RT @leafs_s: Annual Review of Neuroscience An Integrative Theory of Prefrontal Cortex Function https://t.co/SOIln5axUr

May 1, 2023 · 26 shares · 28,042 followers View post →
Eduardo Paul
@eduardoark936 · X

RT @leafs_s: Annual Review of Neuroscience An Integrative Theory of Prefrontal Cortex Function https://t.co/SOIln5axUr

Apr 30, 2023 · 26 shares · 58 followers View post →
Jeong-Kyu Han
@jayhan97 · X

RT @leafs_s: Annual Review of Neuroscience An Integrative Theory of Prefrontal Cortex Function https://t.co/SOIln5axUr

Apr 30, 2023 · 26 shares · 342 followers View post →
Dr Khalid
@rauf_khalid · X

RT @leafs_s: Annual Review of Neuroscience An Integrative Theory of Prefrontal Cortex Function https://t.co/SOIln5axUr

Apr 30, 2023 · 26 shares · 2,484 followers View post →
andres molina
@chuymolina_ · X

RT @leafs_s: Annual Review of Neuroscience An Integrative Theory of Prefrontal Cortex Function https://t.co/SOIln5axUr

Apr 30, 2023 · 26 shares · 319 followers View post →
priya joseph
@ayirpelle · X

RT @leafs_s: Annual Review of Neuroscience An Integrative Theory of Prefrontal Cortex Function https://t.co/SOIln5axUr

Apr 30, 2023 · 26 shares · 4,899 followers View post →
Vishal Bharmauria
@VBharmauria17 · X

RT @leafs_s: Annual Review of Neuroscience An Integrative Theory of Prefrontal Cortex Function https://t.co/SOIln5axUr

Apr 30, 2023 · 26 shares · 116 followers View post →
Milano
@milano_salih · X

RT @leafs_s: Annual Review of Neuroscience An Integrative Theory of Prefrontal Cortex Function https://t.co/SOIln5axUr

Apr 30, 2023 · 26 shares · 456 followers View post →
Peter Suma
@PeterSuma · X

RT @leafs_s: Annual Review of Neuroscience An Integrative Theory of Prefrontal Cortex Function https://t.co/SOIln5axUr

Apr 30, 2023 · 26 shares · 840 followers View post →
De myth ology
@kevinmcld · X

RT @leafs_s: Annual Review of Neuroscience An Integrative Theory of Prefrontal Cortex Function https://t.co/SOIln5axUr

Apr 30, 2023 · 26 shares · 743 followers View post →
Carlos Rebolleda
@RebolledaGil · X

RT @leafs_s: Annual Review of Neuroscience An Integrative Theory of Prefrontal Cortex Function https://t.co/SOIln5axUr

Apr 30, 2023 · 26 shares · 7,753 followers View post →
Christopher Devers
@chrisdevers · X

RT @leafs_s: Annual Review of Neuroscience An Integrative Theory of Prefrontal Cortex Function https://t.co/SOIln5axUr

Apr 30, 2023 · 26 shares · 440 followers View post →
Jose Chavez Martinez
@matracaelcan · X

RT @leafs_s: Annual Review of Neuroscience An Integrative Theory of Prefrontal Cortex Function https://t.co/SOIln5axUr

Apr 30, 2023 · 26 shares · 155 followers View post →
Paco Alarcón Lopez
@paquilloal · X

RT @leafs_s: Annual Review of Neuroscience An Integrative Theory of Prefrontal Cortex Function https://t.co/SOIln5axUr

Apr 30, 2023 · 26 shares · 2,028 followers View post →
Richard Imrich
@richard_imrich · X

RT @leafs_s: Annual Review of Neuroscience An Integrative Theory of Prefrontal Cortex Function https://t.co/SOIln5axUr

Apr 30, 2023 · 26 shares · 154 followers View post →
Jibran Khokhar
@DrJKhokhar · X

RT @leafs_s: Annual Review of Neuroscience An Integrative Theory of Prefrontal Cortex Function https://t.co/SOIln5axUr

Apr 30, 2023 · 26 shares · 10,764 followers View post →
8Eevert ✨
@8Eevert · X

> cognitive control > stems from the prefrontal cortex > active maintenance of goals and means > provide bias signals > establish mappings between inputs, states, and outputs —An integrative theory of prefrontal cortex function. Annu Rev Neurosci. 2001 https://t.co/7BGj5YZ4t2 https://t.co/0ISKClfkeE

Apr 30, 2023 · 3 likes · 1,142 followers View post →
nir
@nirvirain · X

RT @leafs_s: Annual Review of Neuroscience An Integrative Theory of Prefrontal Cortex Function https://t.co/SOIln5axUr

Apr 30, 2023 · 26 shares · 48 followers View post →
Julien Burcher
@Dowellenough · X

RT @leafs_s: Annual Review of Neuroscience An Integrative Theory of Prefrontal Cortex Function https://t.co/SOIln5axUr

Apr 30, 2023 · 26 shares · 1,835 followers View post →
Rodrigo Arzate-Mejía
@RodrigoArzt · X

RT @leafs_s: Annual Review of Neuroscience An Integrative Theory of Prefrontal Cortex Function https://t.co/SOIln5axUr

Apr 30, 2023 · 26 shares · 771 followers View post →
xiping
@xpchern · X

RT @leafs_s: Annual Review of Neuroscience An Integrative Theory of Prefrontal Cortex Function https://t.co/SOIln5axUr

Apr 30, 2023 · 26 shares · 26 followers View post →
DionysusZ
@CryptoZhang_21 · X

RT @leafs_s: Annual Review of Neuroscience An Integrative Theory of Prefrontal Cortex Function https://t.co/SOIln5axUr

Apr 30, 2023 · 26 shares · 184 followers View post →
CLaE
@leafs_s · X

Annual Review of Neuroscience An Integrative Theory of Prefrontal Cortex Function https://t.co/SOIln5axUr

Apr 30, 2023 · 117 likes · 26 shares · 28,042 followers View post →
Medical Xpress
@physorg_health · X

Cognitive flexibility is essential to navigating a changing world—research shows how your #brain learns new rules @ConversationEDU https://t.co/G6S5jgcfV8 https://t.co/DN5I9t4mCy

Apr 27, 2023 · 7,111 followers View post →
⚕ Esme, alias Dra. Molécula
@esmeraldavela · X

Miller EK, Cohen JD. An integrative theory of prefrontal cortex function. Annu Rev Neurosci. 2001;24:167-202. Pope HG, Jr., Yurgelun-Todd D. The residual cognitive effects of heavy marijuana use in college students. JAMA. 1996;275(7):521-7.

Apr 20, 2023 · 5 likes · 3,121 followers View post →
Nagubal Punuvar
@NPunuvar · X

https://t.co/YDNrzYG9yF

Mar 12, 2022 · 137 followers View post →
Seçkin Sosyal
@seckinsosyal · X

RT @MillerLabMIT: @CharanRanganath @JohnKubie @postlelab @celestekidd Simply put, executive functions are the collection of mechanisms unde…

Jan 27, 2022 · 2 shares · 173 followers View post →
Cognitome LLC
@Cognitome11 · X

RT @MillerLabMIT: @CharanRanganath @JohnKubie @postlelab @celestekidd Simply put, executive functions are the collection of mechanisms unde…

Jan 26, 2022 · 2 shares · 136 followers View post →
Earl K. Miller
@MillerLabMIT · X

@CharanRanganath @JohnKubie @postlelab @celestekidd Simply put, executive functions are the collection of mechanisms underlying top-down, goal-directed, behavior. It is a thing because your brain does it. There are lots of reviews but I will plug my own. An oldie but goodie, IMHO. https://t.co/TvtOxjQFhn

Jan 26, 2022 · 33 likes · 2 shares · 41,246 followers View post →
Jordan James Etem
@JordanJamesEtem · X

@Nasdaq @InvescoUS Miller, E.K., Cohen, J.D.: An integrative theory of prefrontal cortex function. Annual Review of Neuroscience 24, 167–202 (2001) $PAYX $MSFT $INTU $FISV $DLTR $ADBE $AMZN $AMGN $CTAS $CTXS @JordanJamesEtem

Aug 14, 2021 · 12,661 followers View post →
Jordan James Etem
@JordanJamesEtem · X

@Teslarati @Writer_01001101 Miller EK, Cohen JD (2001) An integrative theory of prefrontal cortex function. Annu Rev Neurosci 24:167–202 @ArminLaschet @Tesla @elonmusk @karpathy

Aug 13, 2021 · 12,661 followers View post →
Jordan James Etem
@JordanJamesEtem · X

@vonderleyen @europainitalia Miller EK, Cohen JD (2001) An integrative theory of prefrontal cortex function. Annu Rev Neurosci 24:167–202 @VSinkevicius @JuttaUrpilainen @EP_President @FedericaMog @EIB @Lagarde @vonderleyen @satyanadella #ConnectedEconomy #Italy #Europe

Aug 13, 2021 · 12,661 followers View post →
Jordan James Etem
@JordanJamesEtem · X

@Nasdaq Miller EK, Cohen JD (2001) An integrative theory of prefrontal cortex function. Annu Rev Neurosci 24:167–202 @adenatfriedman @farfetch $FTCH

Aug 6, 2021 · 12,661 followers View post →
Jordan James Etem
@JordanJamesEtem · X

@RayDalio Miller EK, Cohen JD (2001) An integrative theory of prefrontal cortex function. Annu Rev Neurosci 24:167–202 @garyvee @vonderleyen @Ronald_vanLoon @VitalikButerin @VanRijmenam @virtualsteve @lindner_juergen @larryellison @PGelsinger @peterthiel @tyler @cameron

Aug 6, 2021 · 12,661 followers View post →
Jordan James Etem
@JordanJamesEtem · X

Miller EK, Cohen JD (2001) An integrative theory of prefrontal cortex function. Annu Rev Neurosci 24:167–202 @MichaelDell @DellFdn https://t.co/j3Ucy9bdV8

Aug 6, 2021 · 12,661 followers View post →
Eino-Mikael Talvitie
@EinoMikael · X

RT @leafs_s: Annual Review of Neuroscience (2001) An Integrative Theory of Prefrontal Cortex Function https://t.co/uJAruyRRTW

Jul 30, 2021 · 2 shares · 18 followers View post →
Kenichiro Nagahama
@k_hammer_1001 · X

RT @leafs_s: Annual Review of Neuroscience (2001) An Integrative Theory of Prefrontal Cortex Function https://t.co/uJAruyRRTW

Jul 29, 2021 · 2 shares · 1,006 followers View post →
CLaE
@leafs_s · X

Annual Review of Neuroscience (2001) An Integrative Theory of Prefrontal Cortex Function https://t.co/uJAruyRRTW

Jul 29, 2021 · 8 likes · 2 shares · 28,042 followers View post →
The WBA Initiative
@wba_initiative · X

An Integrative Theory of Prefrontal Cortex Function (2001) by Miller & Cohen: https://t.co/CuFEmq6mp5

Mar 28, 2021 · 289 followers View post →
Adam J Calhoun
@neuroecology · X

AN INTEGRATIVE THEORY OF PREFRONTAL CORTEX FUNCTION https://t.co/4tM1MKG5hY https://t.co/GgNvDyxBor

Mar 11, 2021 · 1 like · 18,107 followers View post →
Give Me coffee!
@GiveMeCoffeeFla · X

@PcElitest @DoppiGoose @randy_o1970 @ExposingMammon @EscapingAtheism https://t.co/Ywig2WvdvN

Jan 23, 2021 · 1,361 followers View post →
Give Me coffee!
@GiveMeCoffeeFla · X

@DoppiGoose @PcElitest @randy_o1970 @ExposingMammon @EscapingAtheism https://t.co/Ywig2WvdvN

Jan 23, 2021 · 1,361 followers View post →
Matt Weber is out of here
@mattweberphd · X

@samuelmehr Miller & Cohen (2001)! https://t.co/X2xb2N6U8J

Sep 26, 2019 · 1 like · 451 followers View post →