More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synaptic plasticity. Intermittent rate coding and cue-specific ensembles support working memory https://t.co/3EZCdF3QtS #neuroscience
Short-term synaptic plasticity.
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Oct 2019 – Nov 2025Where it's discussed
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X / Twitter103 posts
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Bluesky21 posts
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YouTube2 videos
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News2 articles
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What people are saying
The discussions frequently reference how short-term synaptic plasticity enhances neural network models and working memory, with phrases like 'brain-like networks' and 'robustness,' demonstrating both high interest and perceived impact. The tone is technical and enthusiastic, citing specific examples such as 'facilitation,' 'residual calcium,' and 'chunking neurons,' which highlight the deep engagement and the importance of the article's insights for advancing understanding in neuroscience.
Most discussions recognize the significance of short-term synaptic plasticity in neural function, supporting the publication's findings.
Posts show high curiosity about the mechanisms and applications, especially in working memory and neural modeling.
Many discussions include references to specific models, experimental findings, and implications, indicating deep engagement.
The talks about the role of synaptic plasticity in brain-like network robustness and memory imply the research could influence future neuroscience and AI studies.
Abstract in brief
- Short-term synaptic plasticity involves rapid, activity-dependent changes in synaptic strength that last for a few minutes, influencing how neural networks respond to stimuli.
- Synaptic enhancement, such as facilitation and posttetanic potentiation, is often caused by residual calcium in the presynaptic neuron, which affects the likelihood of neurotransmitter release, while depression typically results from vesicle depletion or feedback mechanisms.
- Various factors like receptor desensitization, glial cell interactions, and genetic or molecular influences also play roles in short-term synaptic changes, affecting how neurons communicate temporarily.
Top posts
Most liked on X and BlueskyMore evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synaptic plasticity. Intermittent rate coding and cue-specific ensembles support working memory www.nature.com/articles/s41... #neuroscience
Thanks to @PedroMediano for inviting me to talk about my PhD project on unconscious working memory simulation using short-term synaptic plasticity in recurrent neural networks at @imperialcollege ! https://t.co/pOa91RueOz
天津大学突破:揭示大脑突触处理时空信息核心机制,为下一代人工智能提供理论基石 Breakthrough at Tianjin University: Interactions between Long- and Short-term Synaptic Plasticity Transform Temporal Neural Representations into Spatial https://t.co/GNyIGmvaV1 https://t.co/1g29MbHnsI
Very interesting for those of us working on mechanisms of short-term synaptic plasticity #biophysics #neuroscience
Alternative splicing of synaptotagmin 7 regulates oligomerization and short-term synaptic plasticity https://t.co/GHyMZpErFR #biorxiv_neursci
All mentions
Understanding Facilitation and Augmentation in Synaptic Plasticity
This video explores presynaptic calcium dynamics and their role in facilitation and augmentation, mechanisms crucial for cortical working memory. It discusses models that leverage short-term synaptic plasticity to…
Understanding Short-term Synaptic Plasticity and Neural Response Modulation
Short-term synaptic plasticity involves rapid, activity-dependent changes in synaptic strength lasting minutes, affecting neural responses. Factors influencing this include residual calcium, vesicle depletion, receptor…
Generalized Wilson-Cowan model with short term synaptic plasticity. https://t.co/rJo2HgsSpt
RT @Compute_King: 天津大学突破:揭示大脑突触处理时空信息核心机制,为下一代人工智能提供理论基石 Breakthrough at Tianjin University: Interactions between Long- and Short-term Syn…
RT @Compute_King: 天津大学突破:揭示大脑突触处理时空信息核心机制,为下一代人工智能提供理论基石 Breakthrough at Tianjin University: Interactions between Long- and Short-term Syn…
天津大学突破:揭示大脑突触处理时空信息核心机制,为下一代人工智能提供理论基石 Breakthrough at Tianjin University: Interactions between Long- and Short-term Synaptic Plasticity Transform Temporal Neural Representations into Spatial https://t.co/GNyIGmvaV1 https://t.co/1g29MbHnsI
Tommaso Trabocchi, Raffaella Burioni, Lucilla de Arcangelis, Duccio Fanelli: Generalized Wilson-Cowan model with short term synaptic plasticity https://arxiv.org/abs/2511.16252 https://arxiv.org/pdf/2511.16252 https://arxiv.org/html/2511.16252
Generalized Wilson-Cowan model with short term synaptic plasticity https://arxiv.org/pdf/2511.16252 Tommaso Trabocchi, Raffaella Burioni, Lucilla de Arcangelis, Duccio Fanelli.
RT @fatihdin4en: We can use this local and online learning rule to create cue-associated attractor fixed-points in RNNs in an unsupervised…
A silent Kv channel subunit shapes PV neuron action potential waveform and short-term synaptic plasticity during high-frequency firing https://t.co/3nX1hztlbC #biorxiv_neursci
A silent Kv channel subunit shapes PV neuron action potential waveform and short-term synaptic plasticity during high-frequency firing https://www.biorxiv.org/content/10.1101/2025.11.06.686832v1
A silent Kv channel subunit shapes PV neuron action potential waveform and short-term synaptic plasticity during high-frequency firing https://www.biorxiv.org/content/10.1101/2025.11.06.686832v1
RT @biorxiv_neursci: Alternative splicing of synaptotagmin 7 regulates oligomerization and short-term synaptic plasticity https://t.co/GHyM…
RT @biorxiv_neursci: Alternative splicing of synaptotagmin 7 regulates oligomerization and short-term synaptic plasticity https://t.co/GHyM…
RT @biorxiv_neursci: Alternative splicing of synaptotagmin 7 regulates oligomerization and short-term synaptic plasticity https://t.co/GHyM…
Alternative splicing of synaptotagmin 7 regulates oligomerization and short-term synaptic plasticity https://t.co/a2GULtvwnJ
Alternative splicing of synaptotagmin 7 regulates oligomerization and short-term synaptic plasticity https://www.biorxiv.org/content/10.1101/2025.10.27.684894v1
Alternative splicing of synaptotagmin 7 regulates oligomerization and short-term synaptic plasticity https://www.biorxiv.org/content/10.1101/2025.10.27.684894v1
Alternative splicing of synaptotagmin 7 regulates oligomerization and short-term synaptic plasticity https://t.co/GHyMZpErFR #biorxiv_neursci
A new study identifies chunking neurons that use short‑term synaptic plasticity to bind items into larger memory chunks, letting working memory hold more than its basic limit. https://getnews.me/synaptic-theory-shows-how-chunking-boosts-working-memory-capacity/ #chunking #workingmemory #neuroscience
#eNeuro | Deletion of Endocannabinoid Synthesizing Enzyme DAGLα in Pcp2-Positive Cerebellar Purkinje Cells Decreases Depolarization-Induced Short–Term Synaptic Plasticity, Reduces Social Preference, and Heightens Anxiety https://t.co/6uWHx3tLmP https://t.co/z7R9ygmxys
#eNeuro | Deletion of Endocannabinoid Synthesizing Enzyme DAGLα in Pcp2-Positive Cerebellar Purkinje Cells Decreases Depolarization-Induced Short–Term Synaptic Plasticity, Reduces Social Preference, and Heightens Anxiety https://doi.org/10.1523/ENEURO.0400-24.2025
"Specifically, net-like ECM acts as lateral diffusion barriers for AMPA receptors, modulating short-term synaptic plasticity" (Ref.: Yong et al, 2024)
Heterogeneity and variability in short term synaptic plasticity and implications for signal transformation Bhalla, U. S., Mohan, S. Paper Details #SynapticPlasticity #NeuroscienceResearch #BhallaMohanStudy
Heterogeneity and variability in short term synaptic plasticity and implications for signal transformation https://www.biorxiv.org/content/10.1101/2025.06.28.662098v1
Heterogeneity and variability in short term synaptic plasticity and implications for signal transformation https://www.biorxiv.org/content/10.1101/2025.06.28.662098v1
A model investigation of short-term synaptic plasticity tuned via Unc13 isoforms. https://www.biorxiv.org/content/10.1101/2025.06.18.660326v1
A model investigation of short-term synaptic plasticity tuned via Unc13 isoforms. https://www.biorxiv.org/content/10.1101/2025.06.18.660326v1
A model investigation of short-term synaptic plasticity tuned via Unc13 isoforms. https://t.co/DIYsdxRJHR #biorxiv_neursci
Synergistic short-term synaptic plasticity mechanisms for working memory https://t.co/nDWFwdcrd1
Synergistic short-term synaptic plasticity mechanisms for working memory https://www.biorxiv.org/content/10.1101/2025.05.07.652583v1
Synergistic short-term synaptic plasticity mechanisms for working memory https://www.biorxiv.org/content/10.1101/2025.05.07.652583v1
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
Short-term synaptic plasticity makes neurons sensitive to the distribution of presynaptic population firing rates published as: https://t.co/3JsF1kC9PR @sfnjournals #biorxiv
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
Very interesting for those of us working on mechanisms of short-term synaptic plasticity #biophysics #neuroscience
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
RT @MillerLabMIT: More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synapt…
More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synaptic plasticity. Intermittent rate coding and cue-specific ensembles support working memory www.nature.com/articles/s41... #neuroscience
More evidence that working memory is not persistent activity. Instead, it is dynamic on/off states with short-term synaptic plasticity. Intermittent rate coding and cue-specific ensembles support working memory https://t.co/3EZCdF3QtS #neuroscience
@GauteEinevoll @PHermanKTHbrain My PhD is about short-term synaptic plasticity in working memory emergence, definitely going to listen carefully to this one!!! Thanks for making this freely available content and congrats!
RT @IgCastillejo: Thanks to @PedroMediano for inviting me to talk about my PhD project on unconscious working memory simulation using short…
RT @IgCastillejo: Thanks to @PedroMediano for inviting me to talk about my PhD project on unconscious working memory simulation using short…
RT @IgCastillejo: Thanks to @PedroMediano for inviting me to talk about my PhD project on unconscious working memory simulation using short…
Thanks to @PedroMediano for inviting me to talk about my PhD project on unconscious working memory simulation using short-term synaptic plasticity in recurrent neural networks at @imperialcollege ! https://t.co/pOa91RueOz
@perpl_lab @Timothy0Leary This paper is significant. WM isn't like an on/off switch. We discuss this in our related studies. Robust and brain-like working memory through short-term synaptic plasticity https://t.co/ZnXVI63r97 Others https://t.co/UxgvxrZ6DG https://t.co/uBbiuRk0lz
It isn't dependent on continuous spiking, that seems clear. Short-term synaptic plasticity has advantages that go beyond memory maintenance. doi.org/10.1371/jour...
Interplay of Long- and Short-term Synaptic Plasticity in a Spiking Network Model of Rat's Episodic Memory https://www.biorxiv.org/content/10.1101/2024.06.21.598805v1
Interplay of Long- and Short-term Synaptic Plasticity in a Spiking Network Model of Rat's Episodic Memory https://www.biorxiv.org/content/10.1101/2024.06.21.598805v1
Literature highlight of the week: Kozachkov et al. show that short-term synaptic plasticity helps to maintain working memories and makes neural networks more robust and brain-like. https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1010776
RT @rhyolight: Live research meeting in about an hour: "Facilitation/augmentation, the pre-synaptic calcium dynamics that are behind it, an…
Live research meeting in about an hour: "Facilitation/augmentation, the pre-synaptic calcium dynamics that are behind it, and hope to touch on how some cortical models have leveraged it as a mechanism to enable/implement cortical working memory." https://t.co/g4cG7pFnCa
At Numenta research meeting tomorrow morning, visiting scholar and neuroscientist Florian Fiebig has a small topic. https://t.co/g4cG7pFnCa
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