Neuroreport July 2002 PMID 12151749

Effect of nicotine and nicotinic receptors on anxiety and depression.

Marina R Picciotto, Darlene H Brunzell, Barbara J Caldarone

Mentions

42
Peak: 6 in Sep 2022
across 5 sources since Feb 2020

Extended reach

82,151
potential audience

Total likes

100

Video views

1,263

Mentions per month

Feb 2020 – Apr 2024

Where it's discussed

  • X / Twitter31 posts
  • News4 articles
  • YouTube3 videos
  • Reddit2 posts
  • Blogs2 articles

AI synopsis

What people are saying

The discussions highlight both supporting evidence that nicotine can act as an antidepressant and anxiolytic and critiques of oversimplified messaging, with examples such as references to scientific reviews and calls to better understand the drug's complex effects, showing a mix of factual engagement and skepticism through word choices like 'false messaging' and 'STOP LYING!'

AgreementModerate agreement

Most discussions recognize that nicotine has both positive and negative effects on anxiety and depression, showing general agreement with the nuanced findings of the publication.

InterestHigh interest

Posts demonstrate high interest, with many referencing scientific evidence, calling out misinformation, or debating implications.

EngagementHigh engagement

The discussions are in-depth, featuring citations of studies, personal opinions, and critiques of messaging from organizations, indicating active and thoughtful engagement.

ImpactModerate impact

While some posts emphasize the importance of understanding nicotine’s complex effects, the overall impact seems moderate as misinformation and debates continue without a consensus shift.

Abstract in brief

  • Nicotine affects anxiety and depression by interacting with nicotinic acetylcholine receptors (nAChRs) in the brain, which can alter stress response and mood.
  • The impact of nicotine on emotional health is complex, capable of reducing or increasing anxiety depending on how, where, and for how long it is used, due to its broad effects on various brain systems.
  • While nicotine can temporarily act as an antidepressant or anti-anxiety agent, chronic use and withdrawal may lead to increased anxiety and depression because of brain adaptations to nicotine exposure.]

Top posts

Most liked on X and Bluesky
Robb Cabansag
@RobbCab · X

The misinformation in @DepressionSticks posts are rampant. Study(https://t.co/UwR4CbCMkr) after study(https://t.co/2iRXXwAMW5) demonstrates nicotine acts as an antidepressant and their entire campaign depends on a correlation from a survey they admit has no evidence of causation https://t.co/HpONgPbcmU

Sep 22, 2021 · 22 likes · 4 shares · 522 followers View post →
Frans Sporsén
@fsporsen · X

Tvärtom finns det indikationer på att nikotin minskar oro och ångest, men att man får oro och ångest vid abstinens om man brukar regelbundet / är beroende. Dvs rätt uppenbart för alla som någonsin rökt/snusat. https://t.co/fCUOxBaPWF

Oct 4, 2021 · 19 likes · 1 share · 7,767 followers View post →
Michael Redfearn
@RedfearnMike · X

@NortheastHealth Nicotine vaping has never caused lung injury. Nicotine has been known as a powerful antidepressant and anxiolitic for decades. By ignoring the mental health challenges that our youth are facing and blaming nicotine,we will harm their mental health further. https://t.co/98SSDmXrCF

Sep 7, 2022 · 8 likes · 1 share · 2,537 followers View post →
Michael Redfearn
@RedfearnMike · X

@truthorange "The ensemble of studies to date suggest that under certain conditions nicotine can act as an anxiolytic and an antidepressant" STOP LYING! https://t.co/98SSDmXrCF

Mar 15, 2022 · 7 likes · 2,537 followers View post →
Zach Evans
@ZachEvans79 · X

@PrueGildea Nicotine for anxiety. https://t.co/i0b8Nb9eUp

Jan 29, 2023 · 3 likes · 2 shares · 380 followers View post →
Michael Redfearn
@RedfearnMike · X

@SamirBecic @EdwardHubert4 @HFRevolution @Clive_Bates Now we can talk about the benefits of nicotine, a.k.a. the reason people smoke or vape. "The ensemble of studies to date suggest that under certain conditions nicotine can act as an anxiolytic and an antidepressant" https://t.co/98SSDmXrCF

Sep 19, 2022 · 2 likes · 2,537 followers View post →

All mentions

Nicotine Age Limit and Effects on Mental Health

In the USA, the legal age to purchase tobacco and e-cigarettes is 21. Nicotine replacement therapies like gum and lozenges are available from age 18. Nicotine impacts anxiety and depression through brain receptors…

Peter Allen · Feb 3, 2020 1,245 views
ChicagoFantasy
@ChicagoFantasy2 · X

@vanillaopinions @nickj_xq @BrentonLengel I’ll assume you’re being genuine. I don’t have access to the full text, but the abstract says exactly what the above tweet states: https://t.co/zRtdxvNz6L This other article points out that smoking makes anxiety worse: https://t.co/SWbva0AmHx

Apr 4, 2024 · 1 like · 37 followers View post →
利権 護 (りけん まもる)
@MOF_JT_NHK_D2_ · X

@Drmiidr 「喫煙は鬱病を悪化させる」という論文ばかりです 「人でも動物でも“特定の条件下において”ニコチンに抗鬱効果がある可能性があるが、ニコチンを慢性的に摂っているとニコチンが切れると鬱が増加」という論文があります この一部を切り取り、タバコ業界が吹聴したのでしょう https://t.co/88aq8BUbhV

Feb 24, 2024 · 1 like · 678 followers View post →
利権 護 (りけん まもる)
@MOF_JT_NHK_D2_ · X

@hasty_jp7 「人でも動物でも “特定の条件下において” ニコチンに抗不安・抗うつ効果がある可能性がある」 ただし 「ニコチンを慢性的に摂っていると、いざニコチンが切れると不安やうつが増加する」ので、結局ダメです。 しかも『ニコチン』単体の話で『タバコ』ではありませんしね https://t.co/88aq8BUbhV

Jan 5, 2024 · 678 followers View post →
bubbles
@shr1eking · X

@protoneutype @BecomingCritter It really isn't though https://t.co/wrBzuY3UQx

Jun 24, 2023 · 1 like · 2,838 followers View post →
Rawg Slinkard
@Rawgster · X

RT @ZachEvans79: @PrueGildea Nicotine for anxiety. https://t.co/i0b8Nb9eUp

Jan 30, 2023 · 2 shares · 2,733 followers View post →
PantherNoster
@PantherNoster · X

RT @ZachEvans79: @PrueGildea Nicotine for anxiety. https://t.co/i0b8Nb9eUp

Jan 30, 2023 · 2 shares · 2,873 followers View post →
Zach Evans
@ZachEvans79 · X

@PrueGildea Nicotine for anxiety. https://t.co/i0b8Nb9eUp

Jan 29, 2023 · 3 likes · 2 shares · 380 followers View post →
Michael Redfearn
@RedfearnMike · X

@SelfMadeHealth @truthinitiative "People who smoke", please. Nicotine has long been known for its antidepressant and anxiolitic properties. You're basically claiming a drug like Xanex causes anxiety, because if I stop taking it, I'll feel anxious. Well no duh.

Oct 11, 2022 · 2 likes · 2,537 followers View post →
Michael Redfearn
@RedfearnMike · X

@SamirBecic @EdwardHubert4 @HFRevolution @Clive_Bates Now we can talk about the benefits of nicotine, a.k.a. the reason people smoke or vape. "The ensemble of studies to date suggest that under certain conditions nicotine can act as an anxiolytic and an antidepressant" https://t.co/98SSDmXrCF

Sep 19, 2022 · 2 likes · 2,537 followers View post →
Michael Redfearn
@RedfearnMike · X

@MEPublicHealth @MalloryGates14 Nicotine has been known as an antidepressant and anxiolitic for decades. Please stop gaslighting people. https://t.co/98SSDmXrCF

Sep 13, 2022 · 2,537 followers View post →
Michael Redfearn
@RedfearnMike · X

@GrimmGreen Nicotine is a known antidepressant and anxiolitic. https://t.co/98SSDmXrCF

Sep 8, 2022 · 1 like · 2,537 followers View post →
Southernvaper
@Southernvaper1 · X

RT @RedfearnMike: @NortheastHealth Nicotine vaping has never caused lung injury. Nicotine has been known as a powerful antidepressant and a…

Sep 7, 2022 · 1 share · 1,591 followers View post →
Michael Redfearn
@RedfearnMike · X

@NortheastHealth Nicotine vaping has never caused lung injury. Nicotine has been known as a powerful antidepressant and anxiolitic for decades. By ignoring the mental health challenges that our youth are facing and blaming nicotine,we will harm their mental health further. https://t.co/98SSDmXrCF

Sep 7, 2022 · 8 likes · 1 share · 2,537 followers View post →
Michael Redfearn
@RedfearnMike · X

@azrulmohdkhalib You've got it backwards. Nicotine is a known antidepressant and anxiolitic. You shouldn't call for prohibition until you understand how a drug may help someone. No one starts consuming nicotine and says, "I love how anxious and depressed this makes me."

Sep 2, 2022 · 1 like · 2,537 followers View post →
W̸y̶a̵t̸t̴
@heckseamon · X

As much as I despise "truth" this is 100% factual, & backed by extensive empirical evidence. Nicotine *can* reduce anxiety/depression in the short term, but long term dependency is proven to cause/exacerbate anxiety, depression, & related disorders. https://t.co/Onn87oZHFq https://t.co/TQnoSu9Ccg

Aug 26, 2022 · 106 followers View post →
Charles A. Gardner, PhD
@ChaunceyGardner · X

@truthinitiative claims nicotine causes depression, anxiety and low attention spans. #FactCheck: Scientific reviews show nicotine 1) reduces depression & anxiety https://t.co/BkdkkArmCB 2) increases focus, attention & memory https://t.co/rWlFJpZC32 @robinkoval @imaracingmom

Jul 1, 2022 · 1 like · 13,491 followers View post →
Rawg Slinkard
@Rawgster · X

RT @RedfearnMike: @vaper_the Thank you for the informative deep five into @truthinitiative's false messaging. https://t.co/98SSDmXrCF

Jul 1, 2022 · 2 shares · 2,733 followers View post →
The Vaper
@vaper_the · X

RT @RedfearnMike: @vaper_the Thank you for the informative deep five into @truthinitiative's false messaging. https://t.co/98SSDmXrCF

Jul 1, 2022 · 2 shares · 3,284 followers View post →
Michael Redfearn
@RedfearnMike · X

@vaper_the Thank you for the informative deep five into @truthinitiative's false messaging. https://t.co/98SSDmXrCF

Jul 1, 2022 · 2 likes · 2 shares · 2,537 followers View post →
Lance Churchill
@LanceChurchill · X

RT @RedfearnMike: @MichaelChaiton Finally, a clear conclusion, Tylenol causes headaches. Good thing we figured that out.. https://t.co/98SS…

Jun 28, 2022 · 2 shares · 5,951 followers View post →
Michael Redfearn
@RedfearnMike · X

@MichaelChaiton Finally, a clear conclusion, Tylenol causes headaches. Good thing we figured that out.. https://t.co/98SSDmXrCF

Jun 28, 2022 · 2 likes · 2 shares · 2,537 followers View post →
Michael Redfearn
@RedfearnMike · X

@truthorange "The ensemble of studies to date suggest that under certain conditions nicotine can act as an anxiolytic and an antidepressant" STOP LYING! https://t.co/98SSDmXrCF

Mar 15, 2022 · 7 likes · 2,537 followers View post →
J Ojibwe
@Jay_Moovee · X

@JoeldWright The effects of nicotine are complex however, and nicotine treatment can be either anxiolytic or anxiogenic depending on the anxiety model tested, the route of nicotine administration and the time course of administration. https://t.co/6okp4uQItD

Oct 9, 2021 · 222 followers View post →
Spellyr
@Sp3llyr · X

RT @fsporsen: Tvärtom finns det indikationer på att nikotin minskar oro och ångest, men att man får oro och ångest vid abstinens om man bru…

Oct 4, 2021 · 1 share · 706 followers View post →
Frans Sporsén
@fsporsen · X

Tvärtom finns det indikationer på att nikotin minskar oro och ångest, men att man får oro och ångest vid abstinens om man brukar regelbundet / är beroende. Dvs rätt uppenbart för alla som någonsin rökt/snusat. https://t.co/fCUOxBaPWF

Oct 4, 2021 · 19 likes · 1 share · 7,767 followers View post →
Ivanna_
@VapinSquirrel · X

RT @RobbCab: The misinformation in @DepressionSticks posts are rampant. Study(https://t.co/UwR4CbCMkr) after study(https://t.co/2iRXXwAMW5)…

Sep 22, 2021 · 4 shares · 1,668 followers View post →
caren cembalest
@CCembalest · X

RT @RobbCab: The misinformation in @DepressionSticks posts are rampant. Study(https://t.co/UwR4CbCMkr) after study(https://t.co/2iRXXwAMW5)…

Sep 22, 2021 · 4 shares · 180 followers View post →
Robb Cabansag
@RobbCab · X

The misinformation in @DepressionSticks posts are rampant. Study(https://t.co/UwR4CbCMkr) after study(https://t.co/2iRXXwAMW5) demonstrates nicotine acts as an antidepressant and their entire campaign depends on a correlation from a survey they admit has no evidence of causation https://t.co/HpONgPbcmU

Sep 22, 2021 · 22 likes · 4 shares · 522 followers View post →
Esrafell
@Esrafell · X

@TazoGumball2345 @KaiThePhaux @G1Gusty @System9509 @yungsnaku Jfc saying some dumb shit behind block? Top Google result https://t.co/hAYREhPpBi https://t.co/xkfKTWxtBU

Feb 8, 2021 · 1 like · 808 followers View post →
Lycha
@lychaxo · X

@Jackabilly @MaggieHulbert @pointandwrite https://t.co/SAYSTbL7OU The same is effectively true of benzodiazepines, though, a group of drugs psychopharmacologically classed as anxiolytics, and their withdrawal can even kill you.

Sep 1, 2020 · 8,590 followers View post →
ana
@iscariotrising · X

@allamaraine4 Ya, several it looks like https://t.co/Q2SLrqomlo https://t.co/iVTJxBuWRN. I’d love to know if/how this relates to Wellbutrin being used as a smoking cessation tool

Apr 17, 2020 · 1 like · 155 followers View post →