Eur J Appl Physiol October 2003 PMID 12883902

Exercise starts and ends in the brain.

Bengt Kayser

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Mentions

20
Peak: 11 in Sep 2021
across 3 sources since Jan 2020

Extended reach

174,855
potential audience

Total likes

83

Video views

389

Mentions per month

Jan 2020 – Nov 2025

Where it's discussed

  • X / Twitter17 posts
  • YouTube2 videos
  • News1 articles

AI synopsis

What people are saying

The collective discussions demonstrate strong agreement with the article, citing phrases like 'exercise starts and ends in the brain' and emphasizing the importance of understanding central fatigue, which indicates a shift away from traditional views. The tone and choice of words reflect high interest and deep engagement, as users reference scientific models and call for further exploration of brain mechanisms in exercise regulation, showcasing the potential impact on exercise science and practices.

AgreementStrong agreement

Most discussions strongly agree with the article's main point that exercise is primarily regulated by the brain, citing phrases like 'Exercise begins and ends in the brain' and emphasizing central fatigue as a key factor.

InterestHigh interest

Participants show high curiosity and engagement, referencing scientific concepts and articles, and expressing interest by mentioning the need to understand brain mechanisms and including quotes from the publication.

EngagementHigh engagement

Posts reference specific models, physiological principles, and share external sources or further information, indicating deep engagement with the topic.

ImpactHigh impact

The discussions highlight a paradigm shift in exercise physiology, emphasizing the central nervous system's role over traditional metabolic models, which suggests a significant influence on current understanding and future research directions.

Abstract in brief

  • Traditional views on exercise endurance focus on the body's metabolic and physiological limits, such as VO2max, muscle fatigue, and glycogen stores.
  • However, at high altitudes and during prolonged exercise, these limits don't fully explain exhaustion, especially when the muscles aren't fatigued and cardiac output is submaximal.
  • An alternative model suggests that the brain actively controls exercise duration by integrating various signals and deciding when to start and stop muscle recruitment to protect the body's overall integrity.

Top posts

Most liked on X and Bluesky
George Nassis
@gnassis · X

This is one of my favorites! @EJAP_official https://t.co/SJUMBdo5nJ

Sep 21, 2021 · 44 likes · 9 shares · 4,368 followers View post →
Tim Noakes
@ProfTimNoakes · X

@TomMcGinn11 Correct. Exercise begins and ends in the brain. https://t.co/6oQacrhoxj Unfortunately much of human exercise physiology has it's roots in Professor AV Hill's (brainless) Cardiovascular/Anaerobic Model of Human Exercise Performance. https://t.co/QRE1htklyD A century later we are

Mar 21, 2025 · 12 likes · 157,858 followers View post →
Matt Boisgontier
@MattBoisgontier · X

"Cardiorespiratory & metabolic capacity are of prime importance in setting the level of performance that can be sustained for a given time, but the central nervous system is ultimately the limiting factor of exercise performance." https://t.co/4ELPI6mco9

Sep 21, 2021 · 2 likes · 1 share · 2,564 followers View post →
Juan R Aguilar
@Picalagartos_ · X

@MVAitor @AndyBeetroot Have you ever considered central fatigue as key factor, above direct metabolic measurements, for a better understanding of this phenomenon? Often, neuromuscular refers only to the spinal motor neuron-muscle pair. However, exercise starts and ends in the brain(Kayser 2003)

Nov 6, 2025 · 2 likes · 437 followers View post →
Brain & Exercise
@BrainExHabit · X

As once said “Exercise starts and ends in the brain” (https://t.co/BLmfnIiWeC) – a reminder that we need to understand the inner workings of the human brain as it relates to voluntary exercise to increase everyday exercise or spontaneous physical activity!

Jan 1, 2020 · 2 likes · 1 share · 54 followers View post →
Juan R Aguilar
@Picalagartos_ · X

@Correndorfinas @WaldenDurden @ChicharroJL Y... este artículo aunque no está en abierto, ya por el título y resumen puedes ver de qué van. Seguro te empieza a interesar la fatiga central, más allá del músculo, de la energía, incluso de la motoneurona espinal. Manda el cerebro! https://t.co/H5qKBj4Zj4

Aug 10, 2022 · 1 like · 437 followers View post →

All mentions

Juan R Aguilar
@Picalagartos_ · X

@MVAitor @AndyBeetroot Have you ever considered central fatigue as key factor, above direct metabolic measurements, for a better understanding of this phenomenon? Often, neuromuscular refers only to the spinal motor neuron-muscle pair. However, exercise starts and ends in the brain(Kayser 2003)

Nov 6, 2025 · 2 likes · 437 followers View post →
Tim Noakes
@ProfTimNoakes · X

@TomMcGinn11 Correct. Exercise begins and ends in the brain. https://t.co/6oQacrhoxj Unfortunately much of human exercise physiology has it's roots in Professor AV Hill's (brainless) Cardiovascular/Anaerobic Model of Human Exercise Performance. https://t.co/QRE1htklyD A century later we are

Mar 21, 2025 · 12 likes · 157,858 followers View post →
Juan R Aguilar
@Picalagartos_ · X

@robertdiezjr @teledeporte La fatiga es un fenómeno complejo que va más allá del gasto energético y las vías oxidativas/fermentativas. Participan factores musculares, endocrinos, y del sistema nervioso central. Te dejo información https://t.co/PhKXf5ExA6 https://t.co/jdnn5AHjy7 https://t.co/A2HYRMjsNo

Mar 2, 2023 · 1 like · 437 followers View post →
Juan R Aguilar
@Picalagartos_ · X

@Correndorfinas @WaldenDurden @ChicharroJL Y... este artículo aunque no está en abierto, ya por el título y resumen puedes ver de qué van. Seguro te empieza a interesar la fatiga central, más allá del músculo, de la energía, incluso de la motoneurona espinal. Manda el cerebro! https://t.co/H5qKBj4Zj4

Aug 10, 2022 · 1 like · 437 followers View post →
Argón
@metilargon · X

RT @gnassis: This is one of my favorites! @EJAP_official https://t.co/SJUMBdo5nJ

Sep 25, 2021 · 9 shares · 353 followers View post →
Doug Renshaw
@doug_renshaw · X

RT @gnassis: This is one of my favorites! @EJAP_official https://t.co/SJUMBdo5nJ

Sep 24, 2021 · 9 shares · 211 followers View post →
daniel varela PhD
@dr_dvarela_P4T · X

RT @gnassis: This is one of my favorites! @EJAP_official https://t.co/SJUMBdo5nJ

Sep 23, 2021 · 9 shares · 922 followers View post →
Alejandro Hernández
@AleexHernz · X

RT @gnassis: This is one of my favorites! @EJAP_official https://t.co/SJUMBdo5nJ

Sep 23, 2021 · 9 shares · 3,936 followers View post →
Artur Negro Vilardell
@arturnegro · X

RT @gnassis: This is one of my favorites! @EJAP_official https://t.co/SJUMBdo5nJ

Sep 22, 2021 · 9 shares · 144 followers View post →
Thiago Lopes, PhD
@trlopes82 · X

RT @gnassis: This is one of my favorites! @EJAP_official https://t.co/SJUMBdo5nJ

Sep 22, 2021 · 9 shares · 786 followers View post →
Bruno Remígio, Ph.D.
@brunooremigio · X

RT @gnassis: This is one of my favorites! @EJAP_official https://t.co/SJUMBdo5nJ

Sep 22, 2021 · 9 shares · 231 followers View post →
Carlos Hernández, PhD(c)
@Carlitos_HM · X

RT @gnassis: This is one of my favorites! @EJAP_official https://t.co/SJUMBdo5nJ

Sep 22, 2021 · 9 shares · 483 followers View post →
Stephen Winrow
@swinrow1 · X

RT @gnassis: This is one of my favorites! @EJAP_official https://t.co/SJUMBdo5nJ

Sep 22, 2021 · 9 shares · 413 followers View post →
Matt Boisgontier
@MattBoisgontier · X

"Cardiorespiratory & metabolic capacity are of prime importance in setting the level of performance that can be sustained for a given time, but the central nervous system is ultimately the limiting factor of exercise performance." https://t.co/4ELPI6mco9

Sep 21, 2021 · 2 likes · 1 share · 2,564 followers View post →
George Nassis
@gnassis · X

This is one of my favorites! @EJAP_official https://t.co/SJUMBdo5nJ

Sep 21, 2021 · 44 likes · 9 shares · 4,368 followers View post →
Prof. Biology
@ResearchBiology · X

RT @BrainExHabit: As once said “Exercise starts and ends in the brain” (https://t.co/BLmfnIiWeC) – a reminder that we need to understand th…

Oct 3, 2020 · 1 share · 637 followers View post →
Brain & Exercise
@BrainExHabit · X

As once said “Exercise starts and ends in the brain” (https://t.co/BLmfnIiWeC) – a reminder that we need to understand the inner workings of the human brain as it relates to voluntary exercise to increase everyday exercise or spontaneous physical activity!

Jan 1, 2020 · 2 likes · 1 share · 54 followers View post →
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News

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