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Overall, these discussions support the article's emphasis on the differences between oral and intravenous vitamin C, with users referencing studies that show IV can achieve plasma levels 70 times higher, and debates over the clinical relevance, tone, and implications of these pharmacokinetic differences, indicating high engagement and recognition of impact.
Most discussions acknowledge the findings that intravenous vitamin C produces significantly higher plasma levels than oral administration, agreeing with the article's implications.
Participants demonstrate high interest by referencing specific data, studies, and debates on dosage and bioavailability, showing engagement with the research details.
There is deep engagement evidenced by quoting the publication, correcting misconceptions, and citing external sources to support points, indicating thorough discussion.
The discussions highlight the importance of the pharmacokinetics findings, emphasizing the potential for high-dose IV vitamin C in therapeutic contexts, reflecting substantial impact.
this is where IV drips come in they deliver vitamins and minerals straight to the bloodstream, ensuring maximum absorption one study found that IV delivered vitamin C resulted in blood levels 70 times higher than oral vitamin C https://t.co/pnlgfYRx8a https://t.co/PiFniE9GHX
Weitere interessante Studien: „Applikation oral vs i.v.“ https://t.co/gW38mzBMZF
@teddybear14151 @gachisoku_diet 量の問題ではなく腸管吸収限界があるから一度に量をとっても下痢しますし タバコ吸ってたり 炎症があれば要求量は増えます 量だけでなく摂取のタイミングもあり 適切なタイミングでとらなければvcの血中濃度は下がります 本を入口に更に探らないと本繰り返しじゃないです https://t.co/A6l9uOxrMv
From the mouth of the NIH "Only intravenous administration of vitamin C produces high plasma and urine concentrations that might have antitumor activity." Shame on everyone who attacked vitamin C intravenously as a quack ! https://t.co/eJe3FrZ0d7
@NocereNihil @Andreli888 https://t.co/gW38mzBMZF https://t.co/UTySGm0unk
@HirataHideaki VCの腸管吸収限界は1回３-４ｇなので3時間おきにのみます 喫煙者とそうでない者では必要量が違います 自分で論文探すようじゃないと他人に聞くようでは学習垢じゃないですよ ビタミンC薬物動態 https://t.co/A6l9uOxrMv
This video explores whether intravenous vitamin C can dissolve blood clots. It discusses the medical consensus on its effectiveness, the marketing surrounding its use in clinics, and the real risks involved in high-dose…
High doses of vitamin C are more toxic to cancer cells in vitro and produce much higher plasma concentrations when administered intravenously compared to orally. Pharmacokinetic studies show intravenous vitamin C can…
This comprehensive video explores Vitamin C through an evidence-based lens, covering its role in collagen production, immune modulation, and athletic recovery. Learn how regular supplementation may reduce cold incidence…
Intravenous vitamin C can achieve 70 fold higher blood levels of ascorbic acid as compared to orally administered This is why the original mayo studies didn’t confirm Paulings results in #cancer https://t.co/Sd07DSZmQj
@Show__Michael 米国では代替治療として高濃度ビタミンＣ点滴は多用されているが、経口(飲む)は意味無し。 非経口つまり点滴はラットに限り有用性を確認したが、進行性腫瘍に対しての確認はされてないと書かれてます。https://t.co/kXI14kuuMy
@DrSyedHaider https://t.co/TobgT8DNed
RT @J__Cub: this is where IV drips come in they deliver vitamins and minerals straight to the bloodstream, ensuring maximum absorption on…
RT @J__Cub: this is where IV drips come in they deliver vitamins and minerals straight to the bloodstream, ensuring maximum absorption on…
RT @J__Cub: this is where IV drips come in they deliver vitamins and minerals straight to the bloodstream, ensuring maximum absorption on…
this is where IV drips come in they deliver vitamins and minerals straight to the bloodstream, ensuring maximum absorption one study found that IV delivered vitamin C resulted in blood levels 70 times higher than oral vitamin C https://t.co/pnlgfYRx8a https://t.co/PiFniE9GHX
RT @doc_maidoc: Weitere interessante Studien: „Applikation oral vs i.v.“ https://t.co/gW38mzBMZF
@NocereNihil @Andreli888 https://t.co/gW38mzBMZF https://t.co/UTySGm0unk
@NocereNihil @Andreli888 Es ist mWn tatsächlich von einer etwas höheren Resorptionsfähigkeit des Darms auszugehen (~ 1000mg), zumindest lt. dieser Studie. Woher haben Sie die 200mg bzw. haben Sie hierzu eine Quelle für mich?
@teddybear14151 @gachisoku_diet 量の問題ではなく腸管吸収限界があるから一度に量をとっても下痢しますし タバコ吸ってたり 炎症があれば要求量は増えます 量だけでなく摂取のタイミングもあり 適切なタイミングでとらなければvcの血中濃度は下がります 本を入口に更に探らないと本繰り返しじゃないです https://t.co/A6l9uOxrMv
@HirataHideaki VCの腸管吸収限界は1回３-４ｇなので3時間おきにのみます 喫煙者とそうでない者では必要量が違います 自分で論文探すようじゃないと他人に聞くようでは学習垢じゃないですよ ビタミンC薬物動態 https://t.co/A6l9uOxrMv
From the mouth of the NIH "Only intravenous administration of vitamin C produces high plasma and urine concentrations that might have antitumor activity." Shame on everyone who attacked vitamin C intravenously as a quack ! https://t.co/eJe3FrZ0d7
Weitere interessante Studien: „Applikation oral vs i.v.“ https://t.co/gW38mzBMZF
@GarethHawker @jbhearn The statement of "The IV dose of 10 g is roughly equivalent to 80 or 100 g orally." is wrong, given the max tolerated oral dose is about 3g every four hours https://t.co/z1N00Rxzj5 and by my reading of this, adding more wont get past the "tightly controlled" uptake in the gut
La #vitaminaC en altas concentraciones es tóxica para las células cancerosas in vitro. Sólo la administración intravenosa de vitamina C produce concentraciones elevadas en plasma y orina que pueden tener actividad antitumoral. https://t.co/8PGFHgefJA https://t.co/MCHuqPzVxS
After oral intake, vitamin C plasma concentrations are tightly controlled at 70 to 85 µmol/L for amounts (as much as 300 mg daily) that can be obtained from food https://t.co/lpWY4I9AND
続き3 薬物動態モデリングで、3gのアスコルビン酸を4時間ごとに投与したとしても、最高血漿中濃度は220micromol/Lに過ぎないことが予想される。 https://t.co/iTl4I6Ufsv
@Lewisdpi @devinnogaki @UnnieM2 @EricTopol @NEJM Agreed, hence my statement: "We report here that intravenous doses can produce plasma concentrations 30- to 70-fold higher than the maximum tolerated oral doses." https://t.co/QdsWqFdEzm
Vitamin C pharmacokinetics: implications for oral and intravenous use. - PubMed - NCBI https://t.co/On3GrgEyoX
To get a clear picture, I'm quotaing from this paper here: https://t.co/dI5HyDZwyi