Nat Neurosci August 2004 PMID 15220929

Epigenetic programming by maternal behavior.

Ian C G Weaver, Nadia Cervoni, Frances A Champagne, Ana C D'Alessio, Shakti Sharma, Jonathan R Seckl, Sergiy Dymov, Moshe Szyf, Michael J Meaney

Mentions

64
Peak: 1 in May 2019
across 6 sources since May 2019

Extended reach

22,961
potential audience

Total likes

18

Video views

24

Mentions per month

May 2019 – Oct 2025

Where it's discussed

  • News24 articles
  • Blogs23 articles
  • X / Twitter8 posts
  • Facebook5 posts
  • YouTube2 videos
  • Reddit2 posts

AI synopsis

What people are saying

Posts express curiosity and admiration for the epigenetics findings, with phrases like 'epigenetics are so cool', and highlight the relevance of maternal behaviors influencing gene expression and stress responses. The tone varies from casual excitement to brief mentions of the study's implications, reflecting general interest without deep technical discussion.

AgreementModerate agreement

The majority of posts acknowledge the importance of the study, with some expressing enthusiasm and support, though a few briefly mention difficulty accessing the full text.

InterestHigh interest

Posts demonstrate high interest, as many highlight the fascinating aspects of epigenetics and maternal influences, even sharing simplified summaries or links to related content.

EngagementModerate engagement

Discussions show moderate engagement, with some users referencing specific researchers, concepts, or requesting additional information, but lacking deep technical analysis.

ImpactModerate impact

There is a recognition of the study’s significance for understanding stress, development, and potential reversibility, although some posts focus more on curiosity than practical implications.

Abstract in brief

  • Maternal behaviors like licking, grooming, and arched-back nursing in rats influence the epigenetic state of the offspring's glucocorticoid receptor gene in the hippocampus, affecting DNA methylation and histone modifications.
  • These epigenetic changes develop early in life, can be reversed with crossfostering, persist into adulthood, and are linked to altered stress responses regulated by the HPA axis.
  • Experimentally blocking histone deacetylation removes these differences, indicating that the maternal behaviors induce epigenomic modifications that impact gene expression and stress regulation, which are potentially reversible.]

Top posts

Most liked on X and Bluesky
Rectum Domini
@ZbrukanyOdbyt · X

@MortTheMortal @mirrex69 @celebert4321 @ManiaPendragon @OliwiaGako20163 Michael Meaney i Moshe Szyf (2004) – “Epigenetic programming by maternal behavior”

Nov 6, 2024 · 5 likes · 16 followers View post →
Mei Imori
@gekkomancer · X

also!!!! here's the paper i was talking about yesterday!!!! https://t.co/wsBgKhiTfI pretty sure the full text is paywalled, so here's a website that explains the gist of the study in layman's terms!!! https://t.co/FrxzJsusPr epigenetics are so cool!!!! wow!!!!!!

Mar 2, 2025 · 4 likes · 871 followers View post →
Sameera Abuaish l سميرة أبوعيش
@SamAbuaish · X

Epigenetic Programming by Maternal Behavior in the Human Infant https://t.co/UUr85jwFuC

Jan 22, 2020 · 2 likes · 164 followers View post →
Real Scientists DE
@realsci_DE · X

Hier übrigens der Link zu einer der Originalstudien: https://t.co/j33Io3V5sl

Oct 14, 2020 · 1 like · 17,972 followers View post →
Trauma-Informed Care Resources
@care_informed · X

Epigenetic Programming by Maternal Behavior in the Human Infant [https://t.co/fW2GASMbTE] https://t.co/rXcU0ZD8Hn

Dec 18, 2019 · 1 like · 1,779 followers View post →
AroDeng
@AroDeng · X

@ztsamudzi @atongatem 2b/ "Epigenetic programming by maternal behavior" - Weaver et. al (Nature Neuroscience, 2004) https://t.co/8OTW0pEn2A https://t.co/gno8oUO64g

Aug 28, 2020 · 1,485 followers View post →

All mentions

Mei Imori
@gekkomancer · X

also!!!! here's the paper i was talking about yesterday!!!! https://t.co/wsBgKhiTfI pretty sure the full text is paywalled, so here's a website that explains the gist of the study in layman's terms!!! https://t.co/FrxzJsusPr epigenetics are so cool!!!! wow!!!!!!

Mar 2, 2025 · 4 likes · 871 followers View post →
Rectum Domini
@ZbrukanyOdbyt · X

@MortTheMortal @mirrex69 @celebert4321 @ManiaPendragon @OliwiaGako20163 Michael Meaney i Moshe Szyf (2004) – “Epigenetic programming by maternal behavior”

Nov 6, 2024 · 5 likes · 16 followers View post →
Gnothi Seauton
@GnoviSeauton · X

@LGeath69802 @bjportraits @FringeViews @JOEBOTxyz @11thBlog

Feb 29, 2024 · 28 followers View post →
Real Scientists DE
@realsci_DE · X

Hier übrigens der Link zu einer der Originalstudien: https://t.co/j33Io3V5sl

Oct 14, 2020 · 1 like · 17,972 followers View post →
AroDeng
@AroDeng · X

@ztsamudzi @atongatem 2b/ "Epigenetic programming by maternal behavior" - Weaver et. al (Nature Neuroscience, 2004) https://t.co/8OTW0pEn2A https://t.co/gno8oUO64g

Aug 28, 2020 · 1,485 followers View post →
Sameera Abuaish l سميرة أبوعيش
@SamAbuaish · X

Epigenetic Programming by Maternal Behavior in the Human Infant https://t.co/UUr85jwFuC

Jan 22, 2020 · 2 likes · 164 followers View post →
Trauma-Informed Care Resources
@care_informed · X

Epigenetic Programming by Maternal Behavior in the Human Infant [https://t.co/fW2GASMbTE] https://t.co/rXcU0ZD8Hn

Dec 18, 2019 · 1 like · 1,779 followers View post →
Epigenética
@Epigenetica · X

New in Pubmed: "Epigenetic Programming by Maternal Behavior in the Human Infant." https://t.co/OevTGwBog5

May 16, 2019 · 622 followers View post →