Ther Drug Monit April 2004 PMID 15228154

Human pharmacology of MDMA: pharmacokinetics, metabolism, and disposition.

Rafael de la Torre, Magí Farré, Pere N Roset, Neus Pizarro, Sergio Abanades, Mireia Segura, Jordi Segura, Jordi Camí

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Mentions

113
Peak: 97 in Nov 2025
across 4 sources since Apr 2023

Extended reach

15,003
potential audience

Total likes

210

Video views

14,594

Mentions per month

Apr 2023 – Nov 2025

Where it's discussed

  • Bluesky97 posts
  • Reddit11 posts
  • X / Twitter3 posts
  • YouTube2 videos

AI synopsis

What people are saying

The collection includes references to the publication's focus on MDMA's pharmacokinetics and metabolism, with some posts expressing appreciation or curiosity, such as repeating the title or discussing its relevance to drug safety. Words like 'human pharmacology' and 'disposition' suggest a recognition of the scientific importance, while expressions of support and recognition of its relevance indicate moderate interest and influence on social discourse.

AgreementModerate agreement

A few discussions specifically support or acknowledge the importance of the publication, indicating some agreement with its significance.

InterestModerate interest

Several posts mention the topic directly, showing an average level of curiosity, but many threads seem tangential or unrelated, limiting overall interest.

EngagementNeutral engagement

Most social discussions show surface-level acknowledgment without deep analysis or detailed critique, reflecting moderate engagement.

ImpactModerate impact

The publication is referenced multiple times in the context of broader health and social issues, hinting at some influence but not creating a major shift in opinions or discussions.

Abstract in brief

  • MDMA, also known as ecstasy, is a popular psychoactive drug that produces feelings of euphoria, increased empathy, and social connection, along with stimulant effects like increased energy and altered perceptions.
  • The drug acts by releasing or inhibiting the reuptake of neurotransmitters such as serotonin, dopamine, and norepinephrine, which leads to its mood-enhancing and stimulant effects, but also can cause acute toxic reactions like serotonin syndrome, hyperthermia, and cardiovascular issues.
  • MDMA metabolism is complex, involving pathways like O-demethylenation and N-dealkylation, with enzyme CYP2D6 playing a role; variations in this enzyme may influence individual susceptibility to toxicity.

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Human pharmacology of MDMA: pharmacokinetics, metabolism, and disposition https://t.co/afceqaNrqD

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Human pharmacology of MDMA: pharmacokinetics, metabolism, and disposition https://t.co/c93pSqzTrE https://t.co/gHBSxrSw6P

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日曜日のむむ ૮ ◜ω◝ ‪ა‬
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お口にあってよかった〜!

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eventually!

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しごおわ

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@laflame21.bsky.social · Bluesky

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Dzień dobry

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this is now an election issue

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Här är dagens händelser:

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@dancingmonk.bsky.social · Bluesky

Thank you

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@melancholytheclown.bsky.social · Bluesky

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@bennyott.bsky.social · Bluesky

Ok, wer soll das denn sein?

Nov 23, 2025 · 1 share View post →
Auf die Bäume ihr Affen
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74 % cirka . Das sind inetwa die selben die die BG. Verschärfungen für gut heißen.

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@ma7mouds5family.myatproto.social · Bluesky

We survived the bombs, but rebuilding our life is the hardest part. My family needs your h@lp every act of kindness matters.

Nov 23, 2025 · 1 share View post →
ノコ
@rbacrnsk89.bsky.social · Bluesky

悪い人だ!!!!!

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@celsovilchez.bsky.social · Bluesky

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@super-pitto.bsky.social · Bluesky

マウスパッドってぺらっぺらになるんだ…

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@bennyott.bsky.social · Bluesky

Klar, liegen schon alle in der Pipeline

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@ckloesch.bsky.social · Bluesky

Tag 47 nach dem Prozess: Herr Wöginger treten Sie zurück!

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@rainswallow0604.bsky.social · Bluesky

なんか合っているようで違うイメージです。文章なのでそのニュアンスが伝えられないことがもどかいしです笑 言い回し・イントネーションともに難しいイメージです

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@theangeldragon.bsky.social · Bluesky

I can't seem to login to my second account @theangeldragon2.bsky.social it keeps saying jwt expired anyone has similar issues?

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Benny
@bennyott.bsky.social · Bluesky

Nov 23, 2025 · 1 share View post →
Au_Pharmacist
@au_pharmacist · X

Human pharmacology of MDMA: pharmacokinetics, metabolism, and disposition https://t.co/c93pSqzTrE https://t.co/gHBSxrSw6P

Jul 23, 2024 · 31 followers View post →
Au_Pharmacist
@au_pharmacist · X

Human pharmacology of MDMA: pharmacokinetics, metabolism, and disposition https://t.co/afceqaNrqD

Oct 26, 2023 · 31 followers View post →
GSAJournals
@GsaJournals · X

Human pharmacology of MDMA: pharmacokinetics, metabolism, and disposition https://t.co/GViuAp2xbG

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https://sci-hub.se/10.1097/00007691-200404000-00009. งั้น MDA คงไม่ใช่สาเหตุของอาการพวกนั้นหรอก น่าจะเป็น MDMA มากกว่า ถ้ากิน MDMA 500 ...

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Besoin d'aide pour une possible overdose : r/MDMA - Reddit
Reddit

https://sci-hub.se/10.1097/00007691-200404000-00009. Donc, le MDA est peu susceptible de causer ces effets. C'est probablement le MDMA lui ...

May 2, 2025 View →
เห็นภาพหลอนๆตอนกิน mdma ป่ะ? : r/MDMA - Reddit
Reddit

https://sci-hub.se/10.1097/00007691-200404000-00009. งั้น MDA คงไม่ใช่สาเหตุของผลข้างเคียงพวกนั้นหรอก น่าจะเป็น MDMA เองมากกว่า ถ้ากิน MDMA ...

Apr 29, 2025 View →
Halusinasyon o psychosis : r/MDMA - Reddit
Reddit

https://sci-hub.se/10.1097/00007691-200404000-00009. Kaya ang MDA ay hindi malamang na maging sanhi ng mga epektong iyon. Malamang ang MDMA ...

Mar 10, 2025 View →
hallucinating : r/MDMA
Reddit

https://sci-hub.se/10.1097/00007691-200404000-00009. So MDA is not very likely to cause those effects. It is probably the MDMA itself. [deleted].

Mar 4, 2025 View →
MDMA zu MDA Umwandlungsrate : r/MDMA - Reddit
Reddit

https://sci-hub.se/10.1097/00007691-200404000-00009. Niederländischer Verweis: https://www.trimbos.nl/wp-content/uploads/sites/31/2021/09 ...

Jan 16, 2025 View →
MDMA to MDA conversion rate : r/MDMA
Reddit

https://sci-hub.se/10.1097/00007691-200404000-00009. Dutch reference: https://www.trimbos.nl/wp-content/uploads/sites/31/2021/09/af1483-acute ...

Jan 16, 2025 View →