Immune regulation of central nervous system functions: from sickness responses to pathological pain.

L R Watkins, S F Maier

February 2005 J Intern Med

Synopsis of Social media discussions

The overall tone reflects a high interest and agreement among the commenters, with mentions of supporting research programs and previous scientists like Lisa Goehler and Linda Watkins highlighting the study’s impact. Words such as 'glad' and references to 'research priorities' emphasize appreciation and perceived importance, contributing to a positive and engaged attitude toward the publication.

A
Agreement
 Moderate agreement

The discussions express support and recognition of the study’s importance, referencing prior research and scientific contributions.

I
Interest
 High level of interest

Many posts indicate a high level of curiosity and appreciation for the research, mentioning specific scientists and research programs.

E
Engagement
 Moderate level of engagement

Comments show moderate engagement, with some referencing personal knowledge and research history, but limited detailed analysis in the discussions.

I
Impact
 Moderate level of impact

The discussions suggest the research is seen as influential within scientific circles, but not yet transformative on a broad societal scale.

Social Mentions

YouTube

2 Videos

Facebook

1 Posts

Twitter

2 Posts

Reddit

3 Posts

Metrics

Video Views

209,957

Total Likes

6,010

Extended Reach

221,034

Social Features

8

Timeline: Posts about article

Top Social Media Posts

Posts referencing the article

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How Our Psychology Is Affected When We Make Mistakes

Making mistakes impacts our brain and influences our psychology by activating immune responses that trigger feelings of stress and discomfort. This interaction highlights how brain-immune system communication affects our mental state, especially during errors.

NA Psikoloji Bilim

November 3, 2020

4,539 views

  • Hassan Khader Ali Yousef
    @hassankhaderali (Twitter)

    RT @MBVanElzakker: @Lindy1715 @domsalisbury @cstroeckw Glad they did this study. It's definitely part of a research program based on the wo…
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    May 17, 2024

    1

  • Michael VanElzakker
    @MBVanElzakker (Twitter)

    @Lindy1715 @domsalisbury @cstroeckw Glad they did this study. It's definitely part of a research program based on the work of scientists I knew as an undergrad like Lisa Goehler https://t.co/8WOa3zmv4E and Linda Watkins https://t.co/nXlaZsVaF9. And yes, this is what I wrote about research priorities at that time https://t.co/wDTnYEAEQz
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    May 17, 2024

    3

    1

  • פוסט מיוחד למזג האוויר הסגרירי. מה קורה במוח כשאנחנו חולים ... - Facebook

    למעוניינים, מקורות נוספים להרחבה: http://onlinelibrary.wiley. com/doi/10.1111/j.1365-2796.2004.01443. x/abstract https://www.sciencedirect.
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    December 17, 2025

    Facebook

  • post covid/autoimmune - brain retraining : r/smallfiberneuropathy

    I really don't think that this is that big a leap. https://onlinelibrary.wiley.com/doi/full/10.1111/j.1365-2796.2004.01443.x. I know a lot of ...
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    May 8, 2024

    Reddit

  • post covid/autoimmun – hjärnreträning : r/smallfiberneuropathy

    ... 10.1111/j.1365-2796.2004.01443.x. Jag känner många inom hjärnomträning som haft kronisk borrelia som blivit bättre eller försvunnit med ...
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    May 8, 2024

    Reddit

  • Is the immune system as a controller of social Behavior a well ...

    ... 10.1111/j.1365-2796.2004.01443.x/full. My lab has also published several papers on immune regulation of behavior. Ohio State actually has ...
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    January 30, 2017

    Reddit

Abstract Synopsis

  • The traditional view of the central nervous system (CNS) and immune system functioning independently has been revised, showing a dynamic interaction where the immune system can influence CNS activities.
  • The immune-to-brain communication triggers sickness responses like fever, fatigue, and increased pain by activating CNS glial cells to release proinflammatory cytokines, which are involved in these processes.
  • Chronic pathological pain may stem from this ancient immune-glial circuitry being hijacked, involving immune and glial cell activation at various nervous system levels, highlighting potential approaches for treating chronic pain syndromes.