September 2004 PMID 15669543

Progesterone: the forgotten hormone in men?

M Oettel, A K Mukhopadhyay

Download social card

Mentions

22
Peak: 3 in Jan 2025
across 5 sources since Jul 2020

Extended reach

420,486
potential audience

Total likes

320

Video views

11,036

Mentions per month

Jul 2020 – Apr 2025

Where it's discussed

  • X / Twitter11 posts
  • Bluesky4 posts
  • News3 articles
  • YouTube2 videos
  • Facebook2 posts

AI synopsis

What people are saying

The discourse reveals strong agreement with the article's argument that progesterone is undervalued in men's health, with comments emphasizing its roles in fertility and overall physiology. Posts use assertive language like ‘very revealing’ and questions about medical practices to demonstrate active engagement, while references to specific studies showcase the deeper exploration of scientific evidence. Overall, the conversations reflect both high interest and a desire for impactful research advances.

AgreementModerate agreement

The majority of discussions acknowledge the importance of progesterone in men and support the need for further research, indicating a general agreement with the article's premise.

InterestHigh interest

Many posts express high interest by questioning current medical perspectives and emphasizing the hormone's role across genders, showing active engagement.

EngagementHigh engagement

Posts include references to scientific studies, personal experiences, and calls for increased research, demonstrating deep engagement and critical thinking.

ImpactModerate impact

Discussions highlight the potential influence on medical practices and understanding of male health, signifying a moderate but meaningful impact within academic and social spheres.

Abstract in brief

  • Progesterone has important roles in men, affecting reproductive functions like sperm development and testosterone production, as well as influencing the central nervous system, immune system, and other organs, yet it remains relatively understudied in male physiology.
  • Despite similar serum progesterone levels in men and women outside of specific menstrual phases, research shows no significant age-related changes in men's progesterone levels, and its effects are often mediated through non-genomic mechanisms, adding complexity to its study and potential treatments.
  • Detecting progesterone receptor isoforms could be valuable for diagnosing prostate issues like benign prostatic hypertrophy and cancer, but the diverse and variable pharmacological effects of progesterone in men highlight the need for more precise therapeutic approaches.]

Top posts

Most liked on X and Bluesky
Mg2+ Papi, the BowTied Mg2+
@Grimhood · X

Progesterone: the forgotten hormone in men? https://t.co/NbLlwiyXAM This paper is very revealing. Suggests progesterone isn’t physiologically relevant except at supraphysiological levels, while having both estrogenic and anti-estrogenic activity dependent on receptor preference.

Apr 3, 2024 · 12 likes · 133,403 followers View post →
Alessandro Loiola MD
@AlessandroLoio2 · X

__ Referências utilizadas para este post: https://t.co/IUQGJXVdlx https://t.co/MvkAdYWCCK https://t.co/tGFvMknn0z https://t.co/tGFvMknn0z https://t.co/FPwlxv7rfH https://t.co/PgkWGyW0tY

Nov 11, 2024 · 7 likes · 223,393 followers View post →
TheUnholyAngell
@TheUnholyAngell · X

Oettel, M., & Mukhopadhyay, A. K. (2004). Progesterone: the forgotten hormone in men?. The aging male : the official journal of the International Society for the Study of the Aging Male, 7(3), 236–257. https://t.co/UQza7vJQ8d

Oct 22, 2024 · 4 likes · 1,012 followers View post →
Rhydian
@indigodecay.bsky.social · Bluesky

My reply won’t be as relevant as others, as I’ve still got ovaries, but I will say, I kept taking progesterone whilst on T (for birth control reasons) and IMO it didn’t interfere in masculinising. Worth acknowledging that cis men need progesterone too, to be healthy - doi: 10.1080/13685530400004199

Feb 12, 2025 · 3 likes · 1 share View post →
entropyisorder
@entropyisorder · X

235/365 Progesterone: the forgotten hormone in men?

Jul 30, 2021 · 1 like · 465 followers View post →
Nicholas (@ultimape) Perry
@ultimape.bsky.wovensoup.com · Bluesky

It should be possible to get the body to make more progesterone regardless of gender status. It's often assumed only cis women make it, but there are aspects here in cis males (that impact fertility) as well. pubmed.ncbi.nlm.nih.gov/15669543/

Oct 15, 2023 · 1 like · 1 share View post →

All mentions

Rhydian
@indigodecay.bsky.social · Bluesky

My reply won’t be as relevant as others, as I’ve still got ovaries, but I will say, I kept taking progesterone whilst on T (for birth control reasons) and IMO it didn’t interfere in masculinising. Worth acknowledging that cis men need progesterone too, to be healthy - doi: 10.1080/13685530400004199

Feb 12, 2025 · 3 likes · 1 share View post →
Wyvernsrose #RaiseTheRate
@wyvernsrose · X

@ProfLizKelly @FemCondition https://t.co/4j0haO6dXO

Jan 7, 2025 · 2,073 followers View post →
Wyvernsrose #RaiseTheRate
@wyvernsrose.bsky.social · Bluesky

pubmed.ncbi.nlm.nih.gov/15669543/

Jan 5, 2025 · 1 share View post →
Wyvernsrose #RaiseTheRate
@wyvernsrose.bsky.social · Bluesky

pubmed.ncbi.nlm.nih.gov/15669543/ can we have more research on this hormone kthx... nope not gonna tell you why

Jan 2, 2025 View post →
Alessandro Loiola MD
@AlessandroLoio2 · X

__ Referências utilizadas para este post: https://t.co/IUQGJXVdlx https://t.co/MvkAdYWCCK https://t.co/tGFvMknn0z https://t.co/tGFvMknn0z https://t.co/FPwlxv7rfH https://t.co/PgkWGyW0tY

Nov 11, 2024 · 7 likes · 223,393 followers View post →
TheUnholyAngell
@TheUnholyAngell · X

Oettel, M., & Mukhopadhyay, A. K. (2004). Progesterone: the forgotten hormone in men?. The aging male : the official journal of the International Society for the Study of the Aging Male, 7(3), 236–257. https://t.co/UQza7vJQ8d

Oct 22, 2024 · 4 likes · 1,012 followers View post →
Mg2+ Papi, the BowTied Mg2+
@Grimhood · X

Progesterone: the forgotten hormone in men? https://t.co/NbLlwiyXAM This paper is very revealing. Suggests progesterone isn’t physiologically relevant except at supraphysiological levels, while having both estrogenic and anti-estrogenic activity dependent on receptor preference.

Apr 3, 2024 · 12 likes · 133,403 followers View post →
Nicholas (@ultimape) Perry
@ultimape.bsky.wovensoup.com · Bluesky

It should be possible to get the body to make more progesterone regardless of gender status. It's often assumed only cis women make it, but there are aspects here in cis males (that impact fertility) as well. pubmed.ncbi.nlm.nih.gov/15669543/

Oct 15, 2023 · 1 like · 1 share View post →
x_mass
@x_mass · X

If you only need progesterone if you have a Uterus then why progesterone critical to health in males? https://t.co/eWBXtLhGss Methinks the NHS is stuck in a 1950's timewarp It's like ignoring that males need Oestrogen to heal everything from sinews to synapes or else they die

Sep 27, 2023 · 108 followers View post →
SpeakOutSister
@speakoutsister · X

@Starlight_x5 @chantecaesar7 @Legsakimbo3 @SahraRaeTaylor https://t.co/JFRmw3mA59

Apr 28, 2023 · 31,758 followers View post →
toronjo_amargo
@AmargoToronjo · X

@basuradetw @IronPatticorti Vas con 19 años de retraso... https://t.co/iEpiw6CK2g

Mar 28, 2023 · 426 followers View post →
WokeAF&UNASHAMED!
@atalanta44 · X

@JosephineVonS @AdrianYalland @colmanc @turner_tom_o @ohnonotphil @BluskyeAllison @WhatIsAWomanBot So you’re unaware that male bodies do actually produce progesterone, oestrogen and LH naturally? https://t.co/grlAurUhdH. Men also produce oestrogen: https://t.co/AJloZ9dX4M. Men also produce LH: https://t.co/qZjCIb5zvb. You don’t even understand the basics of this.

Sep 23, 2022 · 992 followers View post →
entropyisorder
@entropyisorder · X

235/365 Progesterone: the forgotten hormone in men?

Jul 30, 2021 · 1 like · 465 followers View post →
Toomby #MenLearnTheirPlaceChallenge
@toombytoomby · X

@MarlesAway @BBCWomansHour @VikiLovesFACS @imperialcollege See: https://t.co/igLxU8G79z https://t.co/YB6BVefiEd https://t.co/u7VBHwjhOL https://t.co/HJ5VFTLHyR

May 28, 2021 · 413 followers View post →
they/them causing jayhem
@jaythenerdkid · X

@VinaigretteGirl progesterone too https://t.co/uheQEzioki

Jul 5, 2020 · 15,402 followers View post →