July 2005 PMID 15995725

Placebos and painkillers: is mind as real as matter?

Luana Colloca, Fabrizio Benedetti

Download social card

Mentions

8
Peak: 1 in Dec 2021
across 5 sources since Dec 2021

Extended reach

9,884
potential audience

Total likes

110

Video views

945

Mentions per month

Dec 2021 – Nov 2025

Where it's discussed

  • YouTube2 videos
  • Facebook2 posts
  • News2 articles
  • X / Twitter1 posts
  • Bluesky1 posts

AI synopsis

What people are saying

The posts cite specific scientific reviews, highlighting how expectations influence pain modulation, which underscores the article's focus on neurobiological mechanisms and psychological factors, though the tone remains somewhat superficial and informational rather than deeply analytical.

AgreementModerate agreement

Most posts acknowledge the significance of psychological factors like expectation in pain treatment, showing general agreement with the article’s emphasis on mind-body interactions.

InterestModerate interest

Discussions reflect a moderate level of curiosity, with posts noting that the topic is relevant but not deeply explored, as seen in phrases like 'another review' and brief mentions.

EngagementNeutral engagement

There is minimal deep engagement, with posts mainly sharing references and basic summaries rather than detailed critique or personal insights.

ImpactModerate impact

The discourse suggests some recognition of the field's importance, such as referencing how understanding placebo effects could influence treatments, but overall impact appears moderate.

Abstract in brief

  • The text explains that the placebo effect, especially in pain management, involves brain processes that are as real as physical matter, and recent research has better understood these neurobiological mechanisms.
  • It highlights that placebo effects can activate brain mechanisms similar to those triggered by actual painkillers, demonstrating a close link between psychological and physical responses.
  • These scientific advances are influencing how clinical trials are designed and how medical treatments are understood, emphasizing the importance of mind-body interactions.]

Top posts

Most liked on X and Bluesky
Rheum Cat
@rheum_cat · X

Another review on placebo effects https://t.co/rPXC8hH5PK Treatments are not given in a vacuum - expectation can trigger pain modulation #ACR23 #CRC https://t.co/9Q3mbdzj5F

Nov 11, 2023 · 3 likes · 8,893 followers View post →
Rheum Cat
@rheumcat.bsky.social · Bluesky

Another review on placebo effects pubmed.ncbi.nlm.nih.gov/15995725/ Treatments are not given in a vacuum - expectation can trigger pain modulation

Nov 15, 2024 · 3 shares View post →

All mentions

Rheum Cat
@rheumcat.bsky.social · Bluesky

Another review on placebo effects pubmed.ncbi.nlm.nih.gov/15995725/ Treatments are not given in a vacuum - expectation can trigger pain modulation

Nov 15, 2024 · 3 shares View post →
Rheum Cat
@rheum_cat · X

Another review on placebo effects https://t.co/rPXC8hH5PK Treatments are not given in a vacuum - expectation can trigger pain modulation #ACR23 #CRC https://t.co/9Q3mbdzj5F

Nov 11, 2023 · 3 likes · 8,893 followers View post →
New Placebo Effects Theory Explained | PDF | Placebo | Reward ...
News

(2013). 6(7), 545–552. https://doi.org/10.1038/nrn1705 The placebo response in medicine: Minimize, maximize. Colloca, L., & Howick, J. (2018). Placebos ...

Dec 17, 2025 View →
Syed Arsalan Ali ..Proj | PDF | Placebo | Health Care
News

doi:10.1038/nrn1705. PMID 15995725. S2CID 9353193. 110. ^ Benedetti F, Mayberg HS, Wager TD, Stohler CS, Zubieta JK (November 2005). "Neurobiological ...

Dec 17, 2025 View →
1. Terapias pseudocientíficas Personas convencidas de que: • “El ...
Facebook

... 10.1038/nrn1705 • Hossen, M. M., & West, R. (2023). Belief, placebo, and the brain: A systematic review on how beliefs modulate responses to ...

Jul 4, 2025 View →
Dr. José Luis Cordovés Avilés - | Facebook
Facebook

org/10.1038/nrn1705 • Hossen, M. M., & West, R. (2023). Belief, placebo, and the brain: A systematic review on how beliefs modulate ...

Dec 10, 2021 View →