Stroke January 2006 PMID 16339467

Time is brain--quantified.

Jeffrey L Saver

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Mentions

293

Peak: 13 in Oct 2020

across 6 sources since Mar 2019

Extended reach

213,560

potential audience

Total likes

3,107

Video views

44,430

Mentions per month

Mar 2019 – Sep 2025

Where it's discussed

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AI synopsis

What people are saying

Many discussions revolve around the idea that 'time is brain,' highlighting the urgency of swift intervention during strokes. For instance, one participant pointed out that 'every minute without oxygen results in the loss of 1.9 million neurons,' while another emphasized the concept that 'a delay of 10 minutes can mean the difference between mild weakness and complete paralysis.' The tone of urgency in these statements and the specific statistical references illustrate the impactful nature of the article, prompting community members to stress its importance in medical contexts.

AgreementStrong agreement

The majority of discussions reflect a strong consensus on the importance of the article's findings regarding stroke treatment.

InterestHigh interest

Participants exhibit a high level of curiosity about the implications of the findings, as evidenced by the depth of information shared.

EngagementHigh engagement

Contributors engage deeply with the subject, frequently referencing statistics from the article and discussing practical applications.

ImpactHigh impact

The discussions highlight a strong belief in the publication's significance for medical practice and patient care.

Abstract in brief

The phrase "time is brain" highlights the critical importance of rapid evaluation and treatment during a stroke, as nervous tissue is quickly lost.
Recent research shows significant brain loss during acute ischemic strokes, with estimates indicating around 120 million neurons lost per hour and an average final stroke volume of 54 mL.
Without treatment, the brain undergoes aging at an accelerated rate, roughly equivalent to 36 years for every hour of untreated ischemic stroke, underscoring the urgent need for timely medical intervention.

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All mentions

8 Silent Red Flags Your Brain Is in Danger | Stroke Warning Signs You Must Never Ignore (Dr Mandell)

motivationaldoc · Sep 17, 2025 44,363 views

Comparison of Stroke Scales - CCTA Module 9 Assignment 22 Neurologic Emergencies

Kevin Entwistle · Sep 22, 2023 68 views

J M Fritts

@JMFritts2 · X

8 Silent Red Flags Your Brain Is in Danger | Stroke Warning Signs You Mu... https://t.co/AZ7Z5DCVHm via @YouTube

Sep 17, 2025 · 244 followers View post →

Ahmed Naser

@ahmed253182 · X

Oct 21, 2024 · 15 likes · 11,996 followers View post →

Dr Jhunu Mukherjee, MD( Psy)

@JhunuDr · X

Time is Brain -Quantified

May 5, 2024 · 2,332 followers View post →

Augusta Health

@AugustaHealthVA · X

According to the AHA Journal "Time is Brain - Quantified" by Jeffrey L. Saver (2005), the typical patient loses 1.9 million neurons each minute in which stroke is untreated. Visit https://t.co/Bl7LM8YRIk to learn more about Augusta Health's stroke resources. https://t.co/eVUYKvUDe4

Apr 23, 2024 · 1,053 followers View post →

Stephen J. Huett

@huett_j48624 · X

https://t.co/L2IC5RXRcN

Mar 9, 2024 View post →

tetrakis[3,5-bis(trifluoromethyl)phenyl]borate

@betaturn · X

@iowahawkblog If you are actually curious: https://t.co/IEBtin0jfd

Oct 15, 2023 · 1 like · 51 followers View post →

Adept Medical New Zealand

@adeptmedical_nz · X

With 1.9million neurons lost for every minute of ischemia, time lost is a physical brain loss. Help patients receive the right level of stroke care – fast. Improve diagnostic efficiencies & minimise patient head movement with the Adept Head Immobiliser. https://t.co/iUcfrh4zI8 https://t.co/jNrN5EWv27

Jun 2, 2023 · 12 followers View post →

Prof. aNajjar

@ahedNajjar · X

Every minute a stroke is untreated, the average patient loses about 1.9 million brain cells. Jeffrey L. Saver https://t.co/Wp4csg9usb

Apr 26, 2023 · 1 like · 1,023 followers View post →

らじてく@放射線技師

@radi_tech_mri · X

RT @sofadegorogoro: 主幹動脈閉塞を起こした場合の神経細胞の死滅する速さ 1秒で32000個 1分で190万個 1時間で1億2000万個日本人が脳細胞なら、脳梗塞起こしたら１時間で終わる。 https://t.co/eVvacnP0Kx

Apr 19, 2023 · 3 shares · 3,403 followers View post →

ラーメン

@oct_426mhz · X

Apr 19, 2023 · 3 shares · 1,541 followers View post →

thmonk

@thmonk_pf · X

Apr 19, 2023 · 3 shares · 1,636 followers View post →

はんちゃあ。

@sofadegorogoro · X

Apr 19, 2023 · 7 likes · 3 shares · 976 followers View post →

sudershangaur07

@sudershangaur07 · X

https://t.co/wDWY1nxixO https://t.co/l5MjXOSgtH

Apr 1, 2023 · 1,049 followers View post →

Neil Maluste

@NeilMaluste · X

@The_Less_Few @BillyM2k FYI: “The phrase ‘time is brain’ emphasizes that human nervous tissue is rapidly and irretrievably lost as stroke progresses and that therapeutic interventions should be emergently pursued.” https://t.co/l1jglkEUjL

Nov 18, 2022 · 103 followers View post →

Joserra

@jramonfernandez · X

@vick_psi Gracias. La frase no es mía, es una frase empleada desde hace tiempo para enfatizar la importancia del diagnóstico y tratamiento precoz del ictus. https://t.co/ZXhcsbdALU

Aug 4, 2022 · 2 likes · 49,573 followers View post →

migunosuke

@migunosuke · X

@Noboru_Hagino Time is brainですね。 https://t.co/swVbJQ07Fz

Apr 8, 2022 · 2 likes · 1,324 followers View post →

Michal Krawczyk

@4mmk36 · X

@TheSGEM @AlanPlotzker @kenlipartito @GidMK @BrianAlperMD @BMJ_EBM @statsepi It is is in Saver's article https://t.co/3lsSQUXtuS

Mar 27, 2022 · 109 followers View post →

إبراهيم

@ineual · X

RT @farzatalchayah: @ineual المصدر: https://t.co/VJhHp6bvlA

Jan 21, 2022 · 2 shares · 12,706 followers View post →

Farzat Al Chayah

@farzatalchayah · X

@ineual المصدر: https://t.co/VJhHp6bvlA

Jan 21, 2022 · 3 likes · 2 shares · 1,777 followers View post →

Ildeingel

@IldeIngel · X

@sedar_es The concept “Time-is-Brain” versus "Time-is-tissue- brain" [...that 1.9 million brain cells, 14 billion synapses, and 7.5 miles (12 km) of myelinated fibers are lost each minute]. Saver JL. 2006: Time is brain–quantified.

Jan 1, 2022 · 9 followers View post →

Ali Ajrouch

@Ali_Ajrouch · X

RT @rbganatra: In treating stroke, you know the adage "time is brain," but do you know how much? This cool review has estimates: Average…

Nov 28, 2021 · 9 shares · 920 followers View post →

Dicky Yulianda

@dickyyulianda · X

RT @rbganatra: In treating stroke, you know the adage "time is brain," but do you know how much? This cool review has estimates: Average…

Nov 27, 2021 · 9 shares · 248 followers View post →

Rayhan

@Nephwizard · X

RT @rbganatra: In treating stroke, you know the adage "time is brain," but do you know how much? This cool review has estimates: Average…

Nov 27, 2021 · 9 shares · 170 followers View post →

@QueueEdge · X

RT @rbganatra: In treating stroke, you know the adage "time is brain," but do you know how much? This cool review has estimates: Average…

Nov 26, 2021 · 9 shares · 211 followers View post →

Melanie Ripley

@RipleyMelanie · X

RT @rbganatra: In treating stroke, you know the adage "time is brain," but do you know how much? This cool review has estimates: Average…

Nov 26, 2021 · 9 shares · 148 followers View post →

Shreya P. Trivedi MD, MHPE

@ShreyaTrivediMD · X

RT @rbganatra: In treating stroke, you know the adage "time is brain," but do you know how much? This cool review has estimates: Average…

Nov 26, 2021 · 9 shares · 20,473 followers View post →

misswunderwoman

@misswunderwoman · X

RT @rbganatra: In treating stroke, you know the adage "time is brain," but do you know how much? This cool review has estimates: Average…

Nov 26, 2021 · 9 shares · 292 followers View post →

Pavo Roso, Payaso

@dissengagement · X

RT @rbganatra: In treating stroke, you know the adage "time is brain," but do you know how much? This cool review has estimates: Average…

Nov 26, 2021 · 9 shares · 443 followers View post →

Rahul Ganatra

@rbganatra · X

Nov 26, 2021 · 16 likes · 9 shares · 3,912 followers View post →

Michal Krawczyk

@4mmk36 · X

@srrezaie To your points: 1) Advanced imaging showed 'time' is a critical predictor of tissue fate. https://t.co/MiX1ihV5RW 2) Time is also a critical variable in thrombectomy trials, https://t.co/m01Uj2APge Thank you for granting me 2 responses, take care!

Nov 3, 2021 · 109 followers View post →

Luis Andrés Núñez

@AndresLnunez · X

Cada minuto sin tratamiento se pierden 1.9 millones de neuronas, 1.4 billones de sinapsis y 12 km de fibras mielinizadas; en 10 hrs equivale a la pérdida neuronal que ocurre con 26 años de envejecimiento normal. Saver JL. Time is brain quantified. Stroke. 2006; 37(1): 263 - 266

Oct 29, 2021 · 1,582 followers View post →

Andrew Micieli

@MicieliA_MD · X

@FLTDOC1 @TheSGEM @EMS1 @hp_ems @EMSWorldOFCL @DrHowieMell @ZoiNetou @First10EM @broomedocs https://t.co/h5NBTzKXWR

May 18, 2021 · 13,669 followers View post →

Karim Nahra

@knahra1 · X

During a stroke, time is everything! If you have loss of strength or sensation on one side of your body, call the ambulance right away. “The typical patient loses 1.9 million neurons each minute in which stroke is untreated.” https://t.co/JeBrfNvcB9

Mar 28, 2021 · 767 followers View post →

Joshua Budhu

@JoshuaBudhu · X

Every minute counts. For every minute without oxygen, 1.9 million neurons die. That means a delay in 10 minutes can be the difference between some mild weakness and complete paralysis of one side of the body https://t.co/N686iKZXh7.

Mar 23, 2021 · 4 likes · 3,598 followers View post →

MIP guardada

@sharon_edmir · X