Nat Genet March 2006 PMID 16444273

A SNP in the ABCC11 gene is the determinant of human earwax type.

Koh-ichiro Yoshiura, Akira Kinoshita, Takafumi Ishida, Aya Ninokata, Toshihisa Ishikawa, Tadashi Kaname, Makoto Bannai, Katsushi Tokunaga, Shunro Sonoda, Ryoichi Komaki, Makoto Ihara, Vladimir A Saenko, Gabit K Alipov, Ichiro Sekine, Kazuki Komatsu

Mentions

37
Peak: 4 in Dec 2023
across 7 sources since Mar 2011

Extended reach

7,709,720
potential audience

Total likes

21,060

Video views

415,100

Mentions per month

Mar 2011 – Jan 2026

Where it's discussed

  • X / Twitter17 posts
  • News9 articles
  • Facebook4 posts
  • Blogs3 articles
  • YouTube2 videos
  • Bluesky1 posts
  • Reddit1 posts

AI synopsis

What people are saying

The discussions reflect a balanced mix of scientific interest and cultural curiosity, such as mentions of regional differences in earwax type and humorous remarks about deodorants, with posts often using casual or playful language that indicates moderate engagement and recognition of the findings' relevance.

AgreementModerate agreement

Most discussions acknowledge the genetic basis of earwax type, with some emphasizing its significance or amusing aspects, indicating general support.

InterestModerate interest

Posts show moderate curiosity, with some emphasizing cultural or evolutionary implications and others highlighting entertainment value.

EngagementModerate engagement

Comments include references to scientific sources, regional distribution, and cultural observations, showing a decent level of discussion depth.

ImpactNeutral impact

While some posts note the scientific importance, others focus on humorous or superficial aspects, resulting in a moderate perceived impact.

Abstract in brief

  • A specific genetic variant (SNP 538G>A) in the ABCC11 gene determines whether people have wet or dry earwax, with the AA genotype linked to dry earwax and the GA/GG genotypes linked to wet earwax.
  • The allele associated with dry earwax (A) is most common in East Asian populations and shows a geographical gradient worldwide, suggesting it originated in northeast Asia and spread globally.
  • This SNP is notable because it is the first known example of a DNA polymorphism directly responsible for a visible physical trait, like earwax type.]

Top posts

Most liked on X and Bluesky
Alessio Ciaffi
@CiaffiAlessio · X

Nuovo video culmine della serie "Evoluzione e Rutti": - MA LE RAZZE ESISTONO? - Beccatelo qua: https://t.co/384NpTVfPb https://t.co/foVtnw0dQ8

Dec 7, 2023 · 12 likes · 1 share · 1,396 followers View post →
Hermano Grande
@Hermano__Grande · X

@critikallight @p4rtyprophet @qetllrdklk @TheSpergScholar @ulyssesthethird Smell related: https://t.co/gqkijGPxvA https://t.co/7WlHoo82qN https://t.co/E06xVrLnKM Regional Distribution: https://t.co/PDE6x7dRRJ https://t.co/smSyWajGNo

Nov 11, 2024 · 7 likes · 6 followers View post →
音良 林太郎, MD, PhD
@Otola_ryntaro · X

耳垢の遺伝子についての論文 A SNP in the ABCC11 gene is the determinant of human earwax type https://t.co/lZtAL9C1SQ

Jul 7, 2024 · 2 likes · 16,208 followers View post →
Vinod Scaria
@vinodscaria · X

A SNP in the ABCC11 gene is the determinant of human earwax type | Nature Genetics https://t.co/5BjX8cls4Y

Dec 27, 2025 · 2 likes · 12,010 followers View post →
Grok
@grok · X

@puyoquest1 @JTC_ICT @sabakan_tarou 耳垢のタイプとワキガの関係はABCC11遺伝子によるものです。乾いた耳垢(AA型)はワキガが少ない、湿った耳垢(GA/GG型)はワキガの可能性が高い(約80-90%の相関)。ただし100%確定ではない。 ソース: - PubMed: https://t.co/0J577m8dv6 - The Scientist: https://t.co/QCg11LReTi - JST:

Oct 3, 2025 · 1 like · 7,259,802 followers View post →
anya
@marimotes · X

sources: https://t.co/3svdI3WUV3 https://t.co/K9yWIYHaBC https://t.co/KzZx3BW2Te it’s caused by different alleles of the gene, dry earwax is more common in east asia and it’s why ppl complain about Japanese deodorants not working often lol

Feb 24, 2022 · 1 like · 1,511 followers View post →

All mentions

Il Bradipocefalo (ex vecchio e confuso nerd)
@FHeidolon · X

@_illep Qui a cartoni animati (e sono molto bravi) così copriamo tutte le possibilità https://t.co/327c83eTlg

Jan 6, 2026 · 1 like · 560 followers View post →
Vinod Scaria
@vinodscaria · X

A SNP in the ABCC11 gene is the determinant of human earwax type | Nature Genetics https://t.co/5BjX8cls4Y

Dec 27, 2025 · 2 likes · 12,010 followers View post →
Grok
@grok · X

@puyoquest1 @JTC_ICT @sabakan_tarou 耳垢のタイプとワキガの関係はABCC11遺伝子によるものです。乾いた耳垢(AA型)はワキガが少ない、湿った耳垢(GA/GG型)はワキガの可能性が高い(約80-90%の相関)。ただし100%確定ではない。 ソース: - PubMed: https://t.co/0J577m8dv6 - The Scientist: https://t.co/QCg11LReTi - JST:

Oct 3, 2025 · 1 like · 7,259,802 followers View post →
Pippo Baudo
@PippoBa9966269 · X

@RealBlackIrish @martinpes83 @Alefounder43021 @ZibusisoNdiweni @MLangbert https://t.co/hgOg1ryNRt

Jul 25, 2025 · 4 followers View post →
Pippo Baudo
@PippoBa9966269 · X

@Denneska @uncleHsTopGuy https://t.co/FnrBkopz0t

May 28, 2025 · 4 followers View post →
bioZone
@thebiozone.bsky.social · Bluesky

info sources: Yoshiura et al. (2006). Nature Genetics. doi.org/10.1038/ng1733 Toyoda et al. (2009). FASEB. doi.org/10.1096/fj.0... Toyoda et al. (2024). Human Cell. doi.org/10.1007/s135... media sources: biorender.com

Dec 8, 2024 · 1 like View post →
bioZone
@thebiozone · X

sources: Yoshiura et al. (2006). Nature Genetics. https://t.co/Q47KEAGcMd Toyoda et al. (2009). FASEB. https://t.co/azRFb9VEhf Toyoda et al. (2024). Human Cell. https://t.co/87UCzBvYS6

Dec 8, 2024 · 1 like · 189 followers View post →
Hermano Grande
@Hermano__Grande · X

@critikallight @p4rtyprophet @qetllrdklk @TheSpergScholar @ulyssesthethird Smell related: https://t.co/gqkijGPxvA https://t.co/7WlHoo82qN https://t.co/E06xVrLnKM Regional Distribution: https://t.co/PDE6x7dRRJ https://t.co/smSyWajGNo

Nov 11, 2024 · 7 likes · 6 followers View post →
Radish sprouts
@NugolDerp · X

@Zenox_Fake_Name @JoelCuerrier @PPC4Liberty https://t.co/9x5FkvMZnj Guardati questo video, è veloce, divertente e spiega come funzioni il tutto

Oct 29, 2024 · 6 followers View post →
Dave Currà SonofAsgard
@KratosCurr94 · X

Ma le RAZZE ESISTONO? https://t.co/eotClIIGAZ via @YouTube

Sep 18, 2024 · 982 followers View post →
音良 林太郎, MD, PhD
@Otola_ryntaro · X

耳垢の遺伝子についての論文 A SNP in the ABCC11 gene is the determinant of human earwax type https://t.co/lZtAL9C1SQ

Jul 7, 2024 · 2 likes · 16,208 followers View post →
Yuri
@pipebombA_ · X

just watch this bruh. people lack basic understanding of evolution https://t.co/BsPFgnA17p https://t.co/Hv66do3n0b

Jul 3, 2024 · 88 followers View post →
Il Bradipocefalo (ex vecchio e confuso nerd)
@FHeidolon · X

Un ottimo video che spiega perfettamente l'argomento Ma le RAZZE ESISTONO? https://t.co/UPYMyQaUyp via @YouTube

Jan 10, 2024 · 560 followers View post →
Dave Currà SonofAsgard
@KratosCurr94 · X

https://t.co/d3gSIZD40O

Dec 21, 2023 · 982 followers View post →
Alberto Leoni
@AlbertoLeoni11 · X

RT @CiaffiAlessio: Nuovo video culmine della serie "Evoluzione e Rutti": - MA LE RAZZE ESISTONO? - Beccatelo qua: https://t.co/384NpTVfPb h…

Dec 7, 2023 · 1 share · 98 followers View post →
Alessio Ciaffi
@CiaffiAlessio · X

Nuovo video culmine della serie "Evoluzione e Rutti": - MA LE RAZZE ESISTONO? - Beccatelo qua: https://t.co/384NpTVfPb https://t.co/foVtnw0dQ8

Dec 7, 2023 · 12 likes · 1 share · 1,396 followers View post →
anya
@marimotes · X

sources: https://t.co/3svdI3WUV3 https://t.co/K9yWIYHaBC https://t.co/KzZx3BW2Te it’s caused by different alleles of the gene, dry earwax is more common in east asia and it’s why ppl complain about Japanese deodorants not working often lol

Feb 24, 2022 · 1 like · 1,511 followers View post →
Göyqurşağı
@goyqurshaghi · X

Buna görə də Koreyada parfüm satışı digər ölkələrə nisbətən ciddi şəkildə azdır. Mənbələr: doi:10.1038/ng1733 doi:10.1007/s10886-015-0657-8 (2/2)

Nov 13, 2020 · 41 followers View post →
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Jan 6, 2026 View →
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A SNP in the ABCC11 gene is the determinant of human earwax type. Nature Genetics, 38(3), 324–330. https://doi. org/10.1038/ng1733 Yu, Y., Ito, ...

Dec 26, 2024 View →
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... ng1733 (a SNP, 538G → A (rs17822931), in the ABCC11 gene is ... doi: 10.1038/s41598-025-15529-0. 2. The Presence of Active Brown ...

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