Role of genes and environments for explaining Alzheimer disease.

Abstract in brief

• Twin studies have shown that genetics play a significant role in Alzheimer's disease, with heritability estimates around 58% to 79%.
• The study found no major differences in heritability between men and women, and environmental factors also significantly influence the risk of developing AD.
• Genetic factors affect not only the likelihood of developing Alzheimer's but also the age at which symptoms start, especially since differences in the age of onset were more pronounced in dizygotic twins.